Friction melanosis is frequently developed in thin, young woman, on thc covered skin of spinc, rib, elbow, knee and tibia. These lesions range from brown to rcddish-brown in color, appear in either band shapes or reticular patterns, and exhibit no overt syrnptoms. They do not show any inflamatory changes, and the skin remains smooth. According to histopathological findings, the main changcs arc perivascular melanophages on the papillary derrnis and upper dermis, and also increased melanin granules on the basal layer. The following case concern a relatively thin 20-year-o1d female patient. She had a syrwptoniless brown color changcs above the ribs of back, growing in dircction of the ribs for a period of three years. This change was band shaped, but there were no signs of inflammatory reaction, leaving the skin smooth. A biopsy was performed on the relevant tissue, and clinical-histopathological analysis was resulting in diagnosis of friction melanosis.
Biopsy ; Dermis ; Diagnosis ; Dronabinol ; Elbow ; Female ; Friction* ; Humans ; Knee ; Melanins ; Melanosis* ; Ribs ; Skin ; Tibia

Since the pattern of the frequency distribution of a parasite within a host showed an overdispersed pattern, various statistical models such as Poisson, negative binomial and lognormal distributions have been applied on the population dynamics in host-parasite relations. The observed data on the number of metacercariae of Clonorchis sinensis in a suitable intermediate host, Pseudorasbora parva which were collected from an endemic area, Juk-Rim River, Kim-Hae Goon, South Kyong-Sang Do were applied on the statistical models. The results obtained are as follows: By the calculation of the raw data, 258(94.9 percent) out of 272 fish showed positive to the metacercarial infection of C. sinensis. The mean number of metacercaria in a fish was 335.1. The standard deviation was 250.6 and the mode was observed between 250 and 299. The frequency distribution pattern of metacercariae of C. sinensis within the fish host in surveyed area was fitted to the lognormal distribution (0.05 parasitology-helminth-trematoda ; Clonorchis sinensis ; metacercaria ; Pseudorasbora parva ; frequency distribution ; host

To understand the mode of transmission in clonorchiasis, a survey was made in Kim-hae Goon, South Kyong-sang Do (=Province). The mathematical analysis of the age prevalence was done on the egg positive rates. And another analysis for the comparison was also made to the cited data from two areas, North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do. Some catalytic models of H. Muench (1959) were applied to the observed age prevalence. Because the both parameters, such as force of infection(a) and loss of positivity(b) were considered to be constant for a long period in the surveyed area, the two stage catalytic model by Muench was chosen to the analysis. In the surveyed area, Kim-hae Goon where the egg positive rates were 56.2 percent and 61.2 percent (by Kim, 1974), the constant values of 'a' were found to be 0.051 and 0.089 respectively. In other words, the force of infection was 51, 89 per 1,000 susceptibles. The values of 'b' were found to be 0.006 and 0.005. This means that the rates of disappearance from egg positive cases to negative were 6 and 5 per annum per l,000 positive cases in above area. Therefore, the two catalytic curves were expressed by the following equations, y = 1.133 {e(-0.006t) - e(-0.051t)} and y = 1.047 {e(-0.005t) - e(-0.089t)} respectively. In the cases of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do where the egg positive rates of clonorchis shown as 27.7 percent and 15.2 percent by Shin (1964) and Kim (l974), the curves were expressed by y = 1.769 {e(-0.010t) - e(-0.034t)} and y = 2.857 {e(-0.020t) - e(-0.027t)} respectively. From the above mathematical analyses by age prevalence in clonorchiasis, it was considered that the mode of transmission of clonorchiasis in the surveyed area, Kim-hae Goon presented more rapid pattern than those of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do.
parasitology-helminth-trematoda ; clonorchiasis-Clnorchis sinensis ; epidemiology ; transmission

A 33-year-old man had multiple, dome shaped, pin-head sized, hard papules on the center of face and pigeon's egg sized hard tumors on the left upper arm and the trunk. The histopathological findings of the skin biopsy specimens from face and left upper arm showed tumor islands composed of basophilic cells of the same sppearance as basalioma cells, arranged in a lacelike and solid aggregates, without horn cysts.
Adult ; Animals ; Arm ; Basophils ; Biopsy ; Horns ; Humans ; Islands ; Ovum ; Skin

The distribution of transforming growth factor-α (TGF-α) and epidermal growth factor (EGF) in developing mouse embryos of gestational age 8 to 15 days was immunohistochemically (ABC method) studied to investigate the differential expression of these growth factors. Paraffin embedded sections were immunostained with antibodies for TGF-α and EGF. Staining of TGF-α was observed in several organs derived from endoderm, mesoderm and ectoderm in 9-day-old mouse embryos, such as in the heart, optic pit, head mesenchyme, neural tube and primitive gut, and the staining became more intense in 10 to 15-day-old mouse embryos. The staining of EGF was seen in the heart and primitive gut derived from mesoderm and ectoderm respectively, in 9-day-old mouse embryos, but it was observed in other organs as well in 10 to 15-day-old embryos although the intensity was weaker. In the development of heart, immunoreactivity for TGF-α was more intense than EGF, which suggests more active involvement of TGF-α. In the lung, TGF-α staining was observed both in the bronchus and lung bud, whereas EGF staining was seen only the bronchus. In the nervous system, TGF-α was expressed more extensively and more intensively than EGF. In the developing skeletal system, TGF-α staining was stronger and the expression was observed at earlier stage compared with EGF. These results indicate that the activity of TGF-α is more potent than EGF in the development of mouse embryo in general, especially, in the development of mouse heart, nervous system, mesenchyme and skeletal system.
Animals ; Antibodies ; Bronchi ; Ectoderm ; Embryonic Structures* ; Endoderm ; Epidermal Growth Factor* ; Gastrula ; Gestational Age ; Head ; Heart ; Intercellular Signaling Peptides and Proteins ; Lung ; Mesoderm ; Mice* ; Nervous System ; Neural Tube ; Paraffin

No abstract available.
Neurofibromatoses* ; Pseudarthrosis* ; Radius*

No abstract available.
Congenital Abnormalities* ; Humerus* ; Osteotomy*

The results of 17 fractures of tibial shaft treated with Rush nails under the image intensifier and early weight bearing are reported. Thirteen of these fractures were closed. All fractures were united between 12 and 21 weeks clinically, 17 and 26 weeks radiologically after operation. All cases were healed without significant complications, such as fracture disease. The advantages of this method were as follows; 1) normal knee motion and early weight bearingare possible during healing. 2) There is a relatively rapid restoration of bone continuity. This method of treatment for tibial shaft fractures were indicated as follows; 1. Mid-shaft fracture. 2. Segmental fracture of shaft. 3. Expectation of compression force at fracture surface by weight bearing. 4. Open fracture of shaft.
Fractures, Open ; Knee ; Methods ; Tibia ; Weight-Bearing

A case of chondroma of soft tissue of right hand in 23-year old man was reported. The presenting symptom was a slow growing mass, causing mild tenderness. Radiologic examination revealed a well demarked and lobulated calcified mass, was located extraskeletally. Specimen exised from soft tisssue of the hypothenar area of the hand was 5×4×3.5cm sized mass, had gelatinous and gray-whitish appearance. On microscopical examination, the tumor was classified as a chondroma of soft tissue.
Chondroma ; Gelatin ; Hand

In order to compensate the disadvantage of the semirigid and three piece inflatable penile prosthesis. various simple self-contained inflatable penile prostheses have been utilized Recently new self contained inflatable penile prosthesis, Dynaflex was introduced as a modification of previous Hydroflex by AMS. In 25 cases of impotence patients. implantation of penile prosthesis with Dynaflex was performed from July, 1990 to September. 1991. Compared to Hydroflex, Dynaflex was easier to implant and also easier to inflate and deflate. There was no mechanical failure, infection or erosion during follow up period of 3 months to 1 year 6 months. All patients were satisfied with the results of implantation. However in three patients, diameter of 11mm could not be implanted due to smaller diameter of corpus cavenosum of penis. In conclusion, Dynaflex prosthesis could be an attractive alternative to other forms of prosthetic device and new device of Dynaflex is absolutely required for the impotent patient with smaller diameter of his corpus cavernosum.
Erectile Dysfunction ; Follow-Up Studies ; Humans ; Male ; Penile Prosthesis* ; Penis ; Prostheses and Implants