1.Prediction of Biochemical Failure after Radical Prostatectomy for Localized Prostate Cancer.
Jun Hyuk HONG ; Ki Yeol CHOI ; Kyung Hyun MOON ; Choung Soo KIM ; Han Jong AHN
Korean Journal of Urology 2000;41(1):166-173
No abstract available.
Prostate*
;
Prostatectomy*
;
Prostatic Neoplasms*
2.Prediction of Biochemical Failure after Radical Prostatectomy for Localized Prostate Cancer.
Jun Hyuk HONG ; Ki Yeol CHOI ; Kyung Hyun MOON ; Choung Soo KIM ; Han Jong AHN
Korean Journal of Urology 2000;41(1):166-173
No abstract available.
Prostate*
;
Prostatectomy*
;
Prostatic Neoplasms*
3.Prostatic Intraepithelial NeoPlasia in Radical Prostatectomy Specimens as a Prognostic Factor.
Jun Hyuk HONG ; Ki Yeoul CHOI ; Tae Jin LEE ; Jae Y RO ; Choung Soo KIM
Korean Journal of Urology 2000;41(1):147-151
No abstract available.
Prostatectomy*
;
Prostatic Intraepithelial Neoplasia*
4.Prostatic Intraepithelial NeoPlasia in Radical Prostatectomy Specimens as a Prognostic Factor.
Jun Hyuk HONG ; Ki Yeoul CHOI ; Tae Jin LEE ; Jae Y RO ; Choung Soo KIM
Korean Journal of Urology 2000;41(1):147-151
No abstract available.
Prostatectomy*
;
Prostatic Intraepithelial Neoplasia*
5.The Effect of Ondansetron and Metoclopramide on the Prevention of Postoperative Nausea and Vomiting After Using Epidural Morphine-Butorphanol Mixture.
Korean Journal of Anesthesiology 2005;48(5):533-539
BACKGROUND: Neuroaxial morphine may produce nausea and vomiting due to cephalad migration. Though it improves post- operative pain, it may have serious complication delaying recovery. The aim of this study was to investigate the efficacy of prophylactic antiemetics such as conventional metoclopramide or more expensive ondansetron. METHODS: Eighty-seven patients who underwent orthopedic knee arthroscopic surgery under epidural anesthesia were randomly assigned to three groups, which are (a) normal saline intravenous injection control group (Group C), (b) metoclopramide intravenous injection and intranasal spray study group (Group M), (c) ondansetron inravenous injection group (Group O). Before the end of surgery, all patients were given 3 mg of morphine and 2 mg of butorphanol mixture via epidural catheter for postoperative pain control. The anesthesia were all standardized. Post-operative nausea and vomiting were observed and used as outcome variables and postoperative pain, itching, somnolence, dizziness, urinary retention were also observed. RESULTS: The incidence of postoperative nausea was significantly lower in Group M (P = 0.0296) and Group O (P = 0.005) compared with Group C. The incidence of postoperative vomiting was significantly lower in Group O (P = 0.01) compared with Group C. But statistically no difference was noted in vomiting between Group C and Group M (P = 0.0579). CONCLUSIONS: The results suggest that ondansetron and metoclopramide are effective in reducing the incidence of post-operative nausea. But ondansetron is more effective in reducing the incidence of post-operative morphine induced vomiting.
Anesthesia
;
Anesthesia, Epidural
;
Antiemetics
;
Arthroscopy
;
Butorphanol
;
Catheters
;
Dizziness
;
Humans
;
Incidence
;
Injections, Intravenous
;
Knee
;
Metoclopramide*
;
Morphine
;
Nausea
;
Ondansetron*
;
Orthopedics
;
Pain, Postoperative
;
Postoperative Nausea and Vomiting*
;
Pruritus
;
Urinary Retention
;
Vomiting
6.Technetium-99m sestamibi whole Body Scintigraphy in Postoperative Follow-up of Differentiated Thyroid Carcinoma.
Hong Kyu KIM ; Eun Sook KIM ; Young Ki SONG ; Jin Sook RYU ; Dae Hyuk MOON
Journal of Korean Society of Endocrinology 1998;13(4):572-579
BACKGROUND: Recently technetium-99m sestamibi (99mTc MIBI), which dose not require withdrawal of thyroid hormone, has been used for imaging of thyroid carcinoma. The aim of this study was to determine the clinical usefulness of Tc MIBI scintigraphy after total thyroidectomy for thyroid carcinoma. The results were compared with those of standard 131I scintigraphy. METHODS: One hundred twelve patients with a median age of 44 years (range, 14-76 years) were included in the study. After optimal endogenous thyroid stimulating hormone stimulation (>50 mIU/mL), whole body scintigraphy using 4 mCi of 'I and 20 mCi of Tc sestamibi were done simultaneously. Concomitantly serum thyroglobulin and anti-thyroglobulin antibody levels were checked. If abnormal findings on any of the scintigraphic methods or high levels of thyroglobulin (> 10ng/mL) were detected, diagnostic imaging studies were done to confirm the existence of the disease. And high dose (150-200 mCi) 'I was administered as therapy and then whole body scans were performed again after the therapy. The presence or absence of thyroid cancer was established by pathologic, radiologic, and/or high dose I scan findings. RESULTS: In 11 patients, Tc MIBI scan revealed positive accumulations which were not found on 131I scan, of whom 6 had elevated thyroglobulin levels. In these cases, 5 cases were interpreted to have normal thyroid remnant and 6 cases showed pathologic findings (2 lung, 1 lymph node, 1 lung and lymph node, 1 local recurrent cancer, and 1 false positive accumulation of 99mTc MIBI). Metastasis or residual cancer were confirmed histologically in 1 and radiologically in 4 cases. Negative 99mTc MIBI scans, despite of positive I scans, occurred in 9 patients, of whom 2 had abnormal thyroglobulin levels. Seven cases were interpreted to have thyroid remnant, 2 cases were confirmed to have lung metastasis, and another one was misinterpreted due to breast shadow. CONCLUSION: In conclusion, these results suggest that 99mTc MIBI scan may have similar sensitivity and specificity for the detection of residual or metastatic differentiated thyroid carcinoma. The 99mTc MIBI scan, especially in cases of negative 131I scan despite of abnormal thyroglobulin levels, can be used as a very useful complementary diagnostic tool.
Breast
;
Diagnostic Imaging
;
Follow-Up Studies*
;
Humans
;
Lung
;
Lymph Nodes
;
Neoplasm Metastasis
;
Neoplasm, Residual
;
Radionuclide Imaging*
;
Sensitivity and Specificity
;
Technetium Tc 99m Sestamibi
;
Thyroglobulin
;
Thyroid Gland*
;
Thyroid Neoplasms*
;
Thyroidectomy
;
Thyrotropin
;
Whole Body Imaging
7.Clinical Aspects of Inguinal Hernia after Ventriculoperitoneal Shunt.
Hyuk Joon LEE ; Seong Cheol LEE ; Ki Hong KIM ; Sung Eun CHUNG ; Kwi Won PARK ; Woo Ki KIM
Journal of the Korean Association of Pediatric Surgeons 2000;6(2):89-94
Ventriculoperitoneal shunt (VP shunt) for hydrocephalus is thought to inhibit the closure of processus vaginalis by increasing intraabdominal pressure, thus it promotes the inguinal hernia. We reviewed the incidence and characteristics of the inguinal hernia in VP shunted patients, and tried to estimate the patency rate of processus vaginalis in early childhood. A reprospective review of patients undergone insertion of VP shunt between January 1980 and May 1998 at Seoul National University Children Hospital was done. 262 patients were included in this study. Among them, 28 patients developed inguinal hernia (10.7%). Six patients developed inguinal hernia before the insertion of VP shunt. According to the age of VP shunt, the inguinal hernia developed in 16.2% (12/74) of patients who had undergone VP shunt before 6 months old, 12.4% (11/89) between 6 months and 2 years old and 5.1% (5/99) after 2 years old. Among 22 patients excluding 6 patients who developed hernia before VP shunt, the incidence of inguinal hernia after VP shunt was 8.6% (22/256) with male predominance (M:F=18:4). 8 patients developed inguinal hernia bilaterally (36.4%). It is suggested that at least 14% of processus vaginalis is patent until 2 years old.
Child
;
Child, Preschool
;
Hernia
;
Hernia, Inguinal*
;
Humans
;
Hydrocephalus
;
Incidence
;
Infant
;
Male
;
Seoul
;
Ventriculoperitoneal Shunt*
8.A Comparison Technetium-99m and Iodine-123 Scan in Thyroid Hot Nodules.
Eun Sook KIM ; Seok Jun HONG ; Young Ki SONG ; Jin Sook RYU ; Dae Hyuk MOON ; Ki Soo KIM
Journal of Korean Society of Endocrinology 1999;14(2):339-345
BACKGROUND: Pertechnetate ( Tc) has been widely employed for thyroid imaging. While pertechnetate and radioiodide have usually similar results in identifying thyroid nodules, occasionally differences have been noted. We intended to observe that the thyroid nodules which appeared to be hot on pertechnetate and to compare them with the images by radioiodide. METHODS: 'I scan was performed to thirty-eight cases (mean age: 48.9 +/- 13.2) presenting as hot nodule on Tc scan. Thyroid function test and pathologic diagnosis were obtained in all patients. RESULTS: Of the 38 patients, 24 had euthyroidism, 13 had hyperthyroidism, and 1 had hypothyroidism. Thirty patients had adenomatous goiter, 4 papillary carcinoma, 3 Hashimotos thyroiditis, and 1 had HQrthle cell tumor. 28 of 38 patients showed similar images, but the remaining 10 patients(26.3%) revealed discordant images on Tc and 131I scan. Among the concordant cases, 23 had adenomatous goiter, 3 had papillary carcinoma, and 2 had Hashimotos thyroiditis. Among the discordant cases, 7 had adenomatous goiter, 1 had papillary carcinoma, 1 had Hashimotos thyroiditis, and 1 had HQrthle cell tumor. The incidence of malignancy was 10.7% of concordant cases, and 20% of discordant cases and was revealed statistically insignificant (p>0.05). CONCLUSION: We observed higher incidence of malignancy in patients presenting hot nodules on 99mTc scan than ever reported. Fine needle aspiration should be performed to all patients with hot nodules and the 'I scan would not be recommended for further diagnostic study.
Biopsy, Fine-Needle
;
Carcinoma, Papillary
;
Diagnosis
;
Goiter
;
Humans
;
Hyperthyroidism
;
Hypothyroidism
;
Incidence
;
Sodium Pertechnetate Tc 99m
;
Thyroid Function Tests
;
Thyroid Gland*
;
Thyroid Nodule
;
Thyroiditis
9.Customized Cranioplasty Implants Using Three-Dimensional Printers and Polymethyl-Methacrylate Casting.
Bum Joon KIM ; Ki Sun HONG ; Kyung Jae PARK ; Dong Hyuk PARK ; Yong Gu CHUNG ; Shin Hyuk KANG
Journal of Korean Neurosurgical Society 2012;52(6):541-546
OBJECTIVE: The prefabrication of customized cranioplastic implants has been introduced to overcome the difficulties of intra-operative implant molding. The authors present a new technique, which consists of the prefabrication of implant molds using three-dimensional (3D) printers and polymethyl-methacrylate (PMMA) casting. METHODS: A total of 16 patients with large skull defects (>100 cm2) underwent cranioplasty between November 2009 and April 2011. For unilateral cranial defects, 3D images of the skull were obtained from preoperative axial 1-mm spiral computed tomography (CT) scans. The image of the implant was generated by a digital subtraction mirror-imaging process using the normal side of the cranium as a model. For bilateral cranial defects, precraniectomy routine spiral CT scan data were merged with postcraniectomy 3D CT images following a smoothing process. Prefabrication of the mold was performed by the 3D printer. Intraoperatively, the PMMA implant was created with the prefabricated mold, and fit into the cranial defect. RESULTS: The median operation time was 184.36+/-26.07 minutes. Postoperative CT scans showed excellent restoration of the symmetrical contours and curvature of the cranium in all cases. The median follow-up period was 23 months (range, 14-28 months). Postoperative infection was developed in one case (6.2%) who had an open wound defect previously. CONCLUSION: Customized cranioplasty PMMA implants using 3D printer may be a useful technique for the reconstruction of various cranial defects.
Computer-Aided Design
;
Decompressive Craniectomy
;
Follow-Up Studies
;
Fungi
;
Humans
;
Methylmethacrylate
;
Polymethyl Methacrylate
;
Reconstructive Surgical Procedures
;
Skull
;
Tomography, Spiral Computed
10.Prognostic Usefulness of Metabolic Syndrome Compared with Diabetes in Korean Patients with Critical Lower Limb Ischemia Treated with Percutaneous Transluminal Angioplasty.
Ki Bum WON ; Hyuk Jae CHANG ; Sung Jin HONG ; Young Guk KO ; Myeong Ki HONG ; Yangsoo JANG ; Donghoon CHOI
Yonsei Medical Journal 2014;55(1):46-52
PURPOSE: Metabolic syndrome (MS) is a clinical condition that shares many common characteristics with diabetes. However, unlike diabetes, the usefulness of MS as a prognostic entity in peripheral arterial disease is uncertain. This study evaluated the prognostic usefulness of MS in critical lower limb ischemia (CLI) patients. MATERIALS AND METHODS: We compared the 2-year clinical outcomes in 101 consecutive CLI patients (66+/-14 years; 78% men) with 118 affected limbs treated with percutaneous transluminal angioplasty (PTA) according to the presence of MS and diabetes. RESULTS: The number of MS patients was 53 (52%), of which 45 (85%) had diabetes. During a 2-year follow-up, the incidence of clinical outcomes, including reintervention, major amputation, minor amputation, and survival, was not significantly different between MS and non-MS patients; however, the incidence of minor amputation was significantly higher in diabetic than in non-diabetic patients (42% vs. 17%; p=0.011). Cox regression analysis for the 2-year primary patency demonstrated no association between MS and 2-year primary patency [hazard ratio (HR), 1.02; 95% confidence interval (CI), 0.45-2.30; p=0.961], whereas there was a significant association between diabetes and 2-year primary patency (HR, 2.81; 95% CI, 1.02-7.72; p=0.046). Kaplan-Meier analysis revealed no significant difference in the 2-year primary patency between MS and non-MS patients; however, the 2-year primary patency was lower in diabetic than in non-diabetic patients (p=0.038). CONCLUSION: As a prognostic concept, MS might conceal the adverse impact of diabetes on the prognosis of CLI patients treated with PTA.
Aged
;
Aged, 80 and over
;
Angioplasty/*methods
;
Diabetes Mellitus/*therapy
;
Female
;
Humans
;
Ischemia/*therapy
;
Lower Extremity/*blood supply
;
Male
;
Metabolic Syndrome X/*therapy
;
Middle Aged
;
Republic of Korea
;
Retrospective Studies