Since cortison was administered to various clinical conditions, a large number of reports reviewed the influence of its application on the repair process of connective tissue. The effect of cortisone was described as consisting of delayed formation of fibroblast, rnucopolysac-charide and collagen, depressed activity of vitamin D in the human body, disturbed calciurn metabolism and consequently the delayed healing of the fracture. And it was therefore decided to investigate the effect of cortisone on fracture healing process. Twenty male rabbits weighing between 1500 and 2000 gms were used for this experiment. Their ribs were fratured and they were divided in 4 groups as follows: 1st group: control group 2nd group: vitamin. C 15mg/Kg. daily I. M. 3rd group: cortione acetate 20mg/Kg. daily I. M. 4th group: cortisone acetate 20mg/Kg. with vitamin. C 15mg/Kg. daily I, M. Gross and histological changes of healing process of ribs were observed, and results confirmed the delaying effect of cortisone administration in the fracture healing, on the contrary, the vitamin. C administration seemed to accelerate.
Ascorbic Acid ; Collagen ; Connective Tissue ; Cortisone ; Fibroblasts ; Fracture Healing ; Human Body ; Humans ; Male ; Metabolism ; Rabbits ; Ribs ; Vitamin D ; Vitamins

No abstract available.
Polyps* ; Vitelline Duct*

This study aims to investigate the recent clinical and mycological trends of dermatophytoses in Pusan area. The number of patients with dermatophytoses diagnosed by KOH examination and culture at Maryknoll Hospital was 1, 213 during past 2 years from November 1982 to October 1984. The incidence rate of dermatopbytoses was 9. 8% out of 12,377 cases of out patients in total. Tinea pedis (33 .7%,) was the most frequent diagnosis, followed by tinea cruris, tinea unguium, tinea corporis, tinea faciale, tinea manus and tinea capitis, in the order of decreasing frequency. The majority of cases were found in the age group from 20 to 39 4, The over all ratio of male to female patients was ] 2: 1 5 The positive rate in KOH examination was 96. 2A, and it was especially low in the areas of scalp, face and toe webs. The positive culture rate was 55, 9g, and it was higher in the covered area than in the exposed area. 6 678 strains out of the 1, 213 patients were isolated and identified. The species isolated were, in the order of decreasing frequency, Trichophyton rubrum (558 strains, 82.3% of total organisms isolated), Tn'chophyton mentagrophytes (55,8, 1 Microsporum canis (48, 7. 1g) Epidermophyton floccosum (12, 1 8g) and Microsporum gypseum (5, 0. 7gp) Trichophyton rubrum was the major causative organism in all the types of dermatophytoses except tinea capitis and tinea faciale. In tinea capitis, Microsporum canis was the main causative organism, and Trichophyton ferrugineum was not isolated, at all, which was a specific point, compared with the past tendency. In tinea faciale, zoophilic organisms were mainly isolated.
Busan* ; Diagnosis ; Epidermophyton ; Female ; Humans ; Incidence ; Male ; Microsporum ; Onychomycosis ; Outpatients ; Scalp ; Tinea Capitis ; Tinea Pedis ; Tinea* ; Toes ; Trichophyton

Six patients with twenty histologically proven neurilemmomas of the extremities were studied using magnetic resonance(MR) imaging. The size, number, signal intensity on spin-echo T1WI(TR 500-650ms/TE 14-25ms)and gradient -echo (TR 200-600ms/TE 14-20ms; flip angle 25-30)image, enhancement pattern, detectability of nerve of origin, nerve-lesion relationship, and presence of a capsule were analyzed. The masses ranged from 1 to 12cm in longitudinal diameter and originated from the median nerve, ulnar nerve, sciatic nerve, radial nerve, and tibial nerve. All the nerve tracts except for those of 5 lesions, which could not be detected due to their small diameter, were visualized as low intensity tubular structures. All visible nerve tracts were situated along the periphery of the lesion and this finding was considered to be specific for neurilemmona. All neurilemmomas were isointense with the surrounding muscle on spin-echo T1WI and hyperintense on gradient-echo image. After a GD-DTPA injection, all masses showed moderate or marked enhancement and more prominent inhomogeneity than that on nonenhanced scan. In 19 out of 20 lesions(95%), a low signal intensity capsule surrounding the masses could be seen. Four of the six patients showed multiple masses, which was unusual as neurilemmoma usually arises as a solitary mass. In conclusion, the MR findings, especially the eccentric location of the mass lesion from the nerve of origin and the presence of a capsule, were useful in making a diagnosis of neurilemmoma of the extremity and that multiple neurilemmomas were not uncommon.
Diagnosis ; Extremities* ; Gadolinium DTPA ; Humans ; Median Nerve ; Neurilemmoma* ; Radial Nerve ; Sciatic Nerve ; Tibial Nerve ; Ulnar Nerve

No abstract available.
Follow-Up Studies* ; Laser Therapy* ; Prostate*

No abstract available.
Foreign Bodies* ; Pneumonia, Aspiration*

The skin lesions of leprosy have a great similarity to various other lesions. Fasal has called it the great imitator. Sometimes these skin lesions can b misdiagnosed because the physician does not consider leprosy. We reported a case of early lepromatous leprosy in 42 year old male. His skin lesions were similar to secondary syphilid. There were no sensory changes on the skin lesions and no enlargement of the peripheral nerves. Numerous AFB(+) bacilli from the skin smear confirmed our diagnosis of leprosy.
Adult ; Diagnosis ; Humans ; Leprosy ; Leprosy, Lepromatous* ; Male ; Peripheral Nerves ; Skin Manifestations* ; Skin* ; Syphilis, Cutaneous

No abstract available.
Child* ; Humans ; Infant*

Norwegian scabies is a rare clinical variant of human infestation with Sarcoptes sabiei var, hominis, distinguished from the common form of scabies by the presence of remarkable hyperkeratotic scaly crusted skin lesions. We report two cases of Norwegian scabies occuring in a 25-year-old man with merital retardation and in a 9-year-old boy with aplastic anemia, The first case is characterized. by an extensive hyperkeratotic thickening and crusting of the dorsa of hands, knee 8: elbow joints. There is also subungual accumulation of horny rlebris with nail distortion. Histologically, the epidermis shows a mite in straturn comeurn and mild acanthosis in stratum malpighii. Immunoperoxidase for Ig G,M,A is not stained in the clermoepiderrnal junction and capillary wall of upper dermis. The second case shows hyperkeratotic scaly papules and p]aques on the hands, feet, extremities and trunk. 1'he diagnosis vvas confirrned by the demonstration of adults, nymphs, larvas and eggs of Sarcoptes scabiei con the KOH examination of the skin scrapings. hey l3'ords: Norwegian scabies, Mental retardation, Aplastic anemia
Adult ; Anemia, Aplastic ; Capillaries ; Child ; Dermis ; Diagnosis ; Eggs ; Elbow Joint ; Epidermis ; Extremities ; Foot ; Hand ; Humans ; Intellectual Disability ; Knee ; Larva ; Male ; Mites ; Nomifensine ; Nymph ; Ovum ; Sarcoptes scabiei ; Scabies* ; Skin

Primary treatment of cleft palate should result in an intact palate with separation of the oral and nasal cavities. However, the published reports of large series indicate that palatal fistula present in operated cleft palate of a small but significant groups of patients. Even in the best hands, a palatal fistula of the operated cleft palate may reoccur postoperatively. Various methods of repair including local mucosal flaps have been employed to date, but fistula repair is extremely difficult because the operative field is limited by scar formation around the palatal fistula, making wound healing unsatisfactory. In such cases, a tongue flap is commonly indicated. From May of 1991 to May of 1996, among 19 patients with palatal fistula in operated cleft palate, 11 patients were operated by anteriorly-based tongue flap. All patients were followed up for at least 6 months, with mean follow up of 18 months. Among 12 cases of 11 patients included in this study, 11 flaps survived and did not recur during follow up periods. One complication was seen in the first case. In this case, there was a flap detachment from the recipient site on the 3rd postoperative day, but he was treated successfully at a subsequent operation. There have been no problems with feeding and communication until the pedicle is cut, and no patient experienced problems either with alteration in speech or with disturbance of taste sensation following surgery. In conclusion, this study shows that the anteriorly-based tongue flap is a safe and reliable technique for closure of large palatal fistula.
Cicatrix ; Cleft Palate ; Fistula* ; Follow-Up Studies ; Hand ; Humans ; Nasal Cavity ; Palate ; Sensation ; Tongue* ; Wound Healing