1.Systemic Administration of the Potassium Channel Activator in the Polystyrene Latex Bead-Induced Cerebral Vasospasm.
Sung Jo JANG ; Sung Don KANG ; Ki Jung YUN
Journal of Korean Neurosurgical Society 2000;29(6):719-724
No abstract available.
Latex*
;
Polystyrenes*
;
Potassium Channels*
;
Potassium*
;
Vasospasm, Intracranial*
2.Adenosine Deaminase Activities in Sera and Erythrocytes of Patients with Psoriasis.
Kee Yul JANG ; Inn Ki CHUNN ; Young Pio KIM ; Seok Don PARK ; Hyung Sun SOHN
Korean Journal of Dermatology 1984;22(5):471-474
Psoriasis has been known to have various humoral and cellular immune abnormalities. And adenosine deaminase (ADA) activities are known to be decreased in immune deficiency diseases. The present study was designed to measure the activities of ADA in sera and erythrocytes of psoriasis patients by Giustiss method. There were no significant differences in the erythrocytes ADA activities between normal subjects (9, Gp+4 43 units/10 cells) and psoriasis patients (7, 29+3. 64 units /10 cells). The ADA activities in sera of the psoriasis patients (13. 15+3. 43 units/ L) showed lowered activities than those of normal subjects (20. 44-2, 07 units/L).
Adenosine Deaminase*
;
Adenosine*
;
Deficiency Diseases
;
Erythrocytes*
;
Humans
;
Psoriasis*
3.Clinical Observation of Tumors in Children: A second reports of 402 cases.
Hyung Kii KO ; Young Ki JANG ; Don Hee AHN ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1978;21(1):35-48
A total of 402 cases of tumors in children under 15 years of age diagnosed at NMC. During a period of 10 years from Jan. 1996 to Dec. 1975 were analysed clinically and the following results were obtained. 1) 402 tumors were divided into 185 malignant, 72 bign and 25 unclassified tumors. 2) The age distribution showed more higher frequency in the age group of 0~5 than each age group of 6~10 or 11~15 but not significantly. 3) The sex ratio between male and female was same in begin but male preponderanc in malignant tumors. Age group did not affect the sex ratio. 4) Among 402 tumors, leukemia was the commonest neoplasm showing 21% with 84 cases, and somatic soft tissue(57 cases), larynx and lung (36 cases), genitourinary system (35 cases) and skin (29 cases) in given order of frequency. 5) Among 192 begin tumors, the tumors of somatic soft tissue was the commonest(49 cases), and larynx and lung(36 cases), skin(28 cases), G-I tract(15 cases) in gven order of frequency. 6) Among 185 malignant tumors, leukemia was the commonest(45.4 %) and CNS(15.1%), GU system(8.1%) and malignant lymphoma(7.5%) in given order of frequency.
Age Distribution
;
Child*
;
Female
;
Humans
;
Larynx
;
Leukemia
;
Lung
;
Male
;
Sex Ratio
;
Skin
;
Urogenital System
5.A review of subacute necrotizing lymphadenitis.
Chang Hoon JANG ; Soon Seog KWON ; Young Kyoon KIM ; Kwon Hyoung KIM ; Ki Don HAN ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1991;38(3):297-303
No abstract available.
Lymphadenitis*
6.Laparoendoscopic Single-Site Surgery (LESS) for Excision of a Seminal Vesicle Cyst Associated with Ipsilateral Renal Agenesis.
Ki Don JANG ; Kyung Hwa CHOI ; Seung Choul YANG ; Won Sik JANG ; Ji Young JANG ; Woong Kyu HAN
Korean Journal of Urology 2011;52(6):431-433
We report a case of laparoendoscopic single-site surgery (LESS) for a symptomatic left seminal vesicular cyst and ipsilateral renal agenesis. A 49-year-old man presented with a 1-year history of severe irritation upon voiding and intractable, recurrent hematospermia. A computed tomography scan showed a 68x41x38 mm sized left seminal vesicular cyst with ipsilateral renal agenesis. LESS was performed successfully to treat the seminal vesicle cyst. The total operative time was 125 minutes, and blood loss was minimal. The patient was discharged from the hospital on the second postoperative day.
Congenital Abnormalities
;
Hemospermia
;
Humans
;
Kidney
;
Kidney Diseases
;
Laparoscopy
;
Middle Aged
;
Operative Time
;
Seminal Vesicles
;
Surgical Procedures, Minimally Invasive
7.Efficacy of a Multiplex Paclitaxel Emission Stent Using a Pluronic® Mixture Membrane versus a Covered Metal Stent in Malignant Biliary Obstruction: A Prospective Randomized Comparative Study.
Sung Ill JANG ; Se Joon LEE ; Seok JEONG ; Don Haeng LEE ; Myung Hwan KIM ; Hong Jin YOON ; Dong Ki LEE
Gut and Liver 2017;11(4):567-573
BACKGROUND/AIMS: A drug-eluting stent for unresectable malignant biliary obstruction was developed to increase stent patency by preventing tumor ingrowth. The safety and efficacy of a new generation of metallic stents covered with a paclitaxel-incorporated membrane using a Pluronic® mixture (MSCPM-II) were compared prospectively with those of covered metal stents (CMSs) in patients with malignant biliary obstructions. METHODS: This study was initially designed as a prospective randomized trial but was closed early because of a high incidence of early occlusion. Therefore, the data were analyzed using the intent-to-treat method. A total of 72 patients with unresectable distal malignant biliary obstructions were prospectively enrolled. RESULTS: The two groups did not differ significantly in basic characteristics and mean follow-up period (MSCPM-II 194 days vs CMS 277 days, p=0.063). Stent occlusion occurred in 14 patients (35%) who received MSCPM-II and in seven patients (21.9%) who received CMSs. Stent patency and survival time did not significantly differ between the two groups (p=0.355 and p=0.570). The complications were mild and resolved by conservative management in both groups. CONCLUSIONS: There were no significant differences in stent patency or patient survival in MSCPM-II and CMS patients with malignant biliary obstructions.
Biliary Tract Neoplasms
;
Drug-Eluting Stents
;
Follow-Up Studies
;
Humans
;
Incidence
;
Membranes*
;
Methods
;
Paclitaxel*
;
Pancreatic Neoplasms
;
Prospective Studies*
;
Self Expandable Metallic Stents
;
Stents*
8.A case of pulmonary actinomycosis.
Jie Jung JANG ; Sung Su KIM ; Chi Hong KIM ; Soon Seog KWON ; Young Kyoon KIM ; Kwan Hyoung KIM ; Ki Don HAN ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK ; Eun Ju SEO
Tuberculosis and Respiratory Diseases 1992;39(5):438-442
No abstract available.
Actinomycosis*
9.Safety Evaluation of Paclitaxel-Eluting Biliary Metal Stent with Sodium Caprate in Porcine Biliary Tract
Sung Ill JANG ; Seok JEONG ; Don Haeng LEE ; Kun NA ; Sugeun YANG ; Dong Ki LEE
Gut and Liver 2019;13(4):471-478
BACKGROUND/AIMS: Metallic stents designed to relieve malignant biliary obstruction are susceptible to occlusive tumor ingrowth or overgrowth. In a previous report, we described metallic stents covered with paclitaxel-incorporated membrane (MSCPM-I, II) to prevent occlusion from tumor ingrowth via antitumor effect. This new generation paclitaxel-eluting biliary stent is further endowed with sodium caprate (MSCPM-III) for enhanced drug delivery. The purpose of this study is to examine the safety of its drug delivery system in the porcine biliary tract. METHODS: MSCPM-III (10% [wt/vol] paclitaxel) and covered metal stents (CMSs) were endoscopically inserted in porcine bile ducts in vivo. Histologic biliary changes, levels of paclitaxel released, and various serum analytes (albumin, alkaline phosphate, aspartate transaminase, alanine transaminase, total protein, total bilirubin, and direct bilirubin) were assessed. RESULTS: Based on the intensity of reactive inflammation and fibrosis, changes in porcine biliary epithelium secondary to implanted MSCPM-III were deemed acceptable (i.e., safe). Histologic features in the MSCPM-III and CMS groups did not differ significantly. In a related serum analysis, paclitaxel release from MSCPM-III stents was below the limit of detection for 28 days. Biochemical analyses were also similar for the two groups, and no evidence of hepatic or renal toxicity was found in animals receiving MSCPM-III stents. CONCLUSIONS: In a prototypic porcine trial, this newly devised metal biliary stent incorporating both paclitaxel and sodium caprate appears to be safe in the porcine bile duct.
Alanine Transaminase
;
Animals
;
Aspartate Aminotransferases
;
Bile Ducts
;
Biliary Tract Neoplasms
;
Biliary Tract
;
Bilirubin
;
Drug Delivery Systems
;
Drug-Eluting Stents
;
Epithelium
;
Fibrosis
;
Inflammation
;
Limit of Detection
;
Membranes
;
Paclitaxel
;
Pancreatic Neoplasms
;
Self Expandable Metallic Stents
;
Sodium
;
Stents
10.Blue Mold of Pear Caused by Penicillium aurantiogriseum in Korea.
Jae Ouk SHIM ; Kyung Dal CHOI ; Ki Don HAHN ; Jang Hoon LEE ; Ik Hwa HYUN ; Tae Soo LEE ; Kyoung Il KO ; Hai Poong LEE ; Min Woong LEE
Mycobiology 2002;30(2):105-106
The isolation of a causal pathogen from pear fruits showing lesions of blue mold was carried out, which were preserved in the packinghouse of Anseong for the export to the United States. When the lesion of pears (Pyrus pyrifolia Niitaka) was checked in packinghouse, their fruit epidermis over decayed parts varied from light tan to dark brown. Also, the decayed flesh was soft and watery, and separated easily from the healthy tissue. Based on the cultural and morphological characteristics, the fungus (IL-12 isolate) was identified as Penicillium aurantiogriseum. This is the first report associated with blue mold of pear caused by P. aurantiogriseum in Korea.
Epidermis
;
Fruit
;
Fungi*
;
Gyeonggi-do
;
Korea*
;
Penicillium*
;
Pyrus*
;
Triacetoneamine-N-Oxyl
;
United States