1.Korea's Future Technology Forecast in the Fields of Health and Medical Science(2000~2025).
Journal of the Korean Medical Association 2000;43(1):14-28
No abstract available.
2.Evaluation of rep-PCR Genomic Fingerprinting for the Molecular Systematics Study of Yersinia Species.
Young Chan LIM ; Ki Jeong KIM ; Mi Ok SONG ; Chul Min PARK ; Jung Ae LIM ; Won Young KIM ; Sang In CHUNG
Journal of Bacteriology and Virology 2002;32(4):367-380
No abstract available.
Classification*
;
Dermatoglyphics*
;
Yersinia*
3.Comparison of Mepivacaine and Bupivacaine as an Adjuvant of Morphine for Benign Anorectal Surgery under Caudal Anesthesia.
Sung Mun YUN ; Ki Hong PARK ; Jun Sang LIM ; Sung Chul KIM
Journal of the Korean Society of Coloproctology 1998;14(3):517-522
BACKGROUND/AIMS: The caudal anesthsia is most commonly used for benign anorectal surgery, The combination of long-acting anesthetics and opiates has been used for longer duration and successful control of postoperative pain. But the side effects of peridural anesthesics and morphine have commonly occured in caudal anesthesia. This study was performed to assess the difference in clinical effects between peridural mepivacaine and bupivacaine with morphine. METHODS: We evaluated the clinical effects in 60 patients who had anal operation with Jack-Knife position under caudal anesthesia. We divided randomly these 60 patients into two groups, M and B groups (in each group, 30 patients included). Group M (n=30) was given 2% mepivacaine 20 ml with morphine 2 mg caudally, and Group B (n=30) was given 0.5% bupivacaine 20 ml with morphine 2 mg in the same manner. We measured the onset time, duration, postoperative analgesia, and side effects including urinary retention. RESULTS: The onset time for analgesia was significantly shorter in group M than in group B. The duration of postoperative pain complaints was significantly longer in group M than in group B. The postoperative analgesic effects and side effects were not significantly different between two groups. CONCLUSIONS: Caudal mepivacaine and morphine mixture is effective for control of postoperative pain without significant side effects.
Analgesia
;
Anesthesia, Caudal*
;
Anesthetics
;
Bupivacaine*
;
Humans
;
Mepivacaine*
;
Morphine*
;
Pain, Postoperative
;
Urinary Retention
4.Congenital Anonychia of the Toes with Absence of Underlying Phalangeal Bones.
Seong Jin KIM ; Mi Hye LIM ; Seung Chul LEE ; Young Ho WON ; Inn Ki CHUN
Annals of Dermatology 1997;9(3):188-190
Congenital absence of nails usually occur as a rare isolated anomaly or combined with other ectodermal defects. This anomaly is regarded as an inherited disorder either dominantly or recessively but quite a few cases were reported as sporadically developed. The patient was a 2-month-old girl who had no nails on both her 2nd, 3rd toes but had rudimentary nails on her left big toe and both 4th toes at birth. We could not find any other congenital deformity, any family history of inherited diseases related to anonychia. Radiological findings revealed no visualization of both 4th distal phalanges, only. We report this case as congenital anonychia of a sporadic type which may have developed independently from an underlying bone abnormality. We also review other reported cases in the literature.
Congenital Abnormalities
;
Ectoderm
;
Female
;
Hallux
;
Humans
;
Infant
;
Parturition
;
Toes*
5.Apolipoprotein E Polymorphism in Schizophrenic Patients.
Young Sook CHOI ; Chae Ki LIM ; Chul Hyoung LYOO
Journal of Korean Neuropsychiatric Association 2001;40(3):503-509
OBJECTIVES: To explore the role of apolipoprotein E in schizophrenia, we investigated apoli-poprotein E polymorphism in groups of patients with schizophrenia and normal controls. We also examined the relationship of clinical characteristics of schizophrenia to apolipoprotein E genotypes. METHODS: Samples were obtained from 101 schizophrenic patients and 96 controls in Korea and apolipoprotein E polymorphisms were analysed using polymerase chain reaction. RESULTS: The genotype and allele frequencies did not differ from those of controls. The clinical variables of schizophrenia, such as positive and negative groups by PANSS, subtypes by DSM-IV, family history were not associated with each genotypes. CONCLUSION: We could not find the association of apolipoprotein E in Korean schizophrenic patients and it could be suggested that apolipoprotein E isoforms might not play a main role in expression of schizophrenia.
Apolipoproteins*
;
Diagnostic and Statistical Manual of Mental Disorders
;
Gene Frequency
;
Genotype
;
Humans
;
Korea
;
Polymerase Chain Reaction
;
Protein Isoforms
;
Schizophrenia
6.A Case of Lichen Planopilaris.
Mi Hae LIM ; Jong Hyuk PARK ; Seung Chul LEE ; Yong Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1997;35(1):139-143
Lichen planopilaris is believed to be a variant of lichen planus which is occasionally accompanied by classical lichen planus. A 68-year old male had asymptomatic skin colored or light violet colored papules and nodules on the occipital area followed by hair loss for 2 months. He had also violaceous pea to bean sized whitish scaly papules on the right lower extremity. Histopathological examination revealed the dilated follicles to be filled with horny material. There were also intense infiltrations of monocytes which were most prominent at the lower pole of the hair follicles on the scalp lesion. There was also hyperkeratosis, focal hypergranulosis and band-like infiltrations of lymphocytes at the dermo-epidermal junction on the lesion of the lower extremity. Direct immunofluorescence examination showed linear deposition of fibrin at the dermo-epidermal junction in the hair follicles. We had an opportunity to observe a man with lichen planopilaris who had loss of scalp hair which was accompanied by classical lichen planus on the lower extremity.
Aged
;
Fibrin
;
Fluorescent Antibody Technique, Direct
;
Hair
;
Hair Follicle
;
Humans
;
Lichen Planus
;
Lichens*
;
Lower Extremity
;
Lymphocytes
;
Male
;
Monocytes
;
Peas
;
Scalp
;
Skin
;
Viola
7.A Case of Acropustulosis of Infancy.
Young Chul JUNG ; Ki Ho LEE ; Choong Rim HAW ; Jai Il YOON ; Soo Duk LIM
Korean Journal of Dermatology 1983;21(2):195-199
Acropustulosis of infancy is an uncommon, but not rare syndrome established as a new disease entity by Kahn and Rywlin(1976), which is characterized by recurrent, intensely pruritic vesicopustules on the distal extremities. We'd like to report a case of acropustulosis of infancy. Our patient was 19 month old girl who had been suffering from her skin disease since the age of 12 months. Intensely pruritic, 1 to 2 mm vesicopustules erupted on the palms, soles and the ventral aspects of the fingers. There were no bacteria, fungus and parasites(Sarcoptes scabiei) on the pustular lesions. Histopathologically, biopsy specimen of the left sole revealed large, well circumscribed intraepidermal pustule which was filled wth polymorphonuclear leukocytes. We confirmed our case as typical case of acropustulosis of infancy by it's characteristic clinical features and histopathologic findings. Severity of the skin lesions seems closely related to the dosage of dapsone. The eruptions were unresponsive to topical steroid, antibiotics and antihistaminics. But we observed that dapsone has dose dependent relationship with acropustulosis of infancy.
Anti-Bacterial Agents
;
Bacteria
;
Biopsy
;
Dapsone
;
Extremities
;
Female
;
Fingers
;
Fungi
;
Humans
;
Infant
;
Neutrophils
;
Skin
;
Skin Diseases
8.A case report of Angle's Class II, division 1, subdivision.
Chul Joong LIM ; Joong Ki KIM ; Won Sick YANG ; Hee Won CHO
Korean Journal of Orthodontics 1970;1(1):38-42
No abstract available.
9.A case report of Angle's Class III subdivision.
Joong Ki KIM ; Chul Joong LIM ; Won Sick YANG ; Hee Won CHO
Korean Journal of Orthodontics 1970;1(1):43-46
No abstract available.
10.Clinical values of CT and dynamic CT in brain infarction
Soo Il LIM ; Do JANG ; Eun Joo SEO ; Myung Hee SOHN ; Ki Chul CHOI
Journal of the Korean Radiological Society 1985;21(2):199-208
With the advent of faster scan time and new computer program, a scanning technique called “dynamic computedtomography” has become possible. Dynamic CT consists of performing multiple rappid sequence scans after injectionof contrast material. The authors have evaluated the clinical usefulness of CT and dynamic CT of 93 patients withbrain infarction and/or ischemia during the period of 17 months from April 1983 to Aug. 1983 to Aug. 1984 inDepartment of Radiology, Chonbuk National University Hospital. The results were as follows; 1. The agedistribution ranged from 18 years to 78 years. Among them the most common age group was between 50 years and 59years(40.9%). 2. The sites of brain infarction were cerebral lobes(63 cases,68), basal ganglia(15 cases, 16.1%)and mlultiple sites(6 cases, 6.4%). The common affected site was middle cerebral artery territories. 3. Thecontrast enhancement of acute infarction was noted in 14 cases(17.5%) which occured commonly between 3 days and 2weeks from ictus. 4. The patterns of time-density curve in brain infarction and/or ischemia were as follow: a .Depression of slow wash-in phase was 20 cases(59%). b. Lower peak concentration was 17 cases(50%), c. Lower anddelayed peak concentration was 7 cases(21%), d. No definite peak concentration was 6 cases(18%). First threepatterns of time-density curve were thought as relatively characteristic curve of brain infarction and/orischemia. 5. Two cases that showed negative findings on precontrast CT scan appeared to be positive findings ashypodensity on postcontrast CT scan and were confirmed as brain infarction by dynamic CT. 6. The diagnostic entityof dynamic CT scan were as follows: a. large artery thrombotic infarction were 23 cases (58%). b. lacunarinfarction were 6 cases (15%). c. ischemia were 5 cases (13%), d. normal were 5 cases(13%), In six cases oflacunar infarction which was doubtful hypodensity on pre-and postcontrast CT scan had a marked difference in CT#(HU) on absolute scale graph of dynamic CT, so diagnosis of lacunar infarction could be made easily. 7. Theclinical values of dynamic CT consist in not only diagnosis of lacunar infarction but also evaluation ofeffectiveness of medical or surgical treatment.
Arteries
;
Brain Infarction
;
Brain
;
Depression
;
Diagnosis
;
Humans
;
Infarction
;
Ischemia
;
Jeollabuk-do
;
Middle Cerebral Artery
;
Stroke, Lacunar
;
Tomography, X-Ray Computed