3.A study of expression of EGFR and ER as prognostic factors of breast cancer.
Journal of the Korean Cancer Association 1993;25(3):368-375
No abstract available.
Breast Neoplasms*
;
Breast*
4.Two Cases of Left Atrial Myxoma.
Korean Circulation Journal 1991;21(3):620-625
Atrial myxomas are uncommon, but surgical treatment offers a potential cure. Early diagnosis is essential so that tumors can be promptly removed in order to reduce morbidity or mortality from atrioventricular valve dysfunction and embolic complications. They are intracavitary tumors occurring within any of the cardiac chambers, but they have a predilection for the atria, particulary the left atrium. The development of noninvasive, echocardiogaphic technique has made it possible to screen large numbers of patients with atrial myxoma with ease and safty. Recently the development of diagnostic procedure and cardiac surgery increased the accuracy of diagnosis and the opportunity of successful ereatment. We report the two cases of left artial myxomas which were removed successfully by surgery.
Diagnosis
;
Early Diagnosis
;
Echocardiography
;
Heart Atria
;
Humans
;
Mortality
;
Myxoma*
;
Thoracic Surgery
6.Factors Associated with Stress Symptoms In Korean Dental Laboratory Technicians.
Ji Hwan KIM ; Won Chul LEE ; Kang Sook LEE ; Chul LEE ; Ki Nam JIN
Korean Journal of Occupational and Environmental Medicine 2000;12(4):501-514
OBJECTIVES: To investigate the factors associated with symptoms from job stress among Korean dental laboratory technicians. METHODS: We collected the data of 786 technicians for life-style, job stressor, social support, self-esteem, personality, and various dimension of stress symptoms included roomatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, and hostility by self-administerd questionnaire. Global severity index of dental technician (GSID) was calculated by total sum of sub-dimension. RESULTS: We used 80 percentile as a cut-off point, and got the 81.5 % of sensitivity, 86.1 % of specificity by receiver operating characteristic curve. The odds ratios of various factors in high group of GSID compared with low group were 1,49(95 % Cl 1.00-2.00) for smoker, 1,53 (1.06-2.21) for unhealthy group, 6,69 (4.74-9.44) for work overload, 8.34(5.82-11.97) for work demand, 9.89 (6.76-74.94) for work process, 8.27 (5.80-11,79) for work environment, 5.82 (4.04-8.39) for interpersonal relationship, 8.34 (5.82-11.97) for occupational conflict, 5.70 (4.04-8.04) for labor remuneration, 7.58 (5.37-10.71) for role conflict, but 0.39 (0.27-0.57) for social support, 0.41 (0.29-0.60) for self-esteem. By multiple logistic regression, factors were significantly associated with GSID were age, working area, role overload, work demand, work procedure, physical environment, occupational conflict, role conflict, social support, personality traits. CONCLUSIONS: Factors associated with symptoms from stress were role overload, work demand, work procedure, occupational conflict, interpersonal relationship, labor remuneration and role conflict in Korean dental laboratory technicians. It is suggested that health promotion program to reduce job stress and to enforce social support and self-esteem should be developed.
Anxiety
;
Dental Technicians
;
Depression
;
Health Promotion
;
Hostility
;
Humans
;
Laboratories, Dental*
;
Logistic Models
;
Odds Ratio
;
Questionnaires
;
Remuneration
;
ROC Curve
;
Sensitivity and Specificity
7.Receptors for murine monoclonal antibodies on the normal blood cells.
Joon Ki JUNG ; Myung Chul LEE ; Chang Soon KOH
Journal of the Korean Cancer Association 1993;25(2):252-260
No abstract available.
Antibodies, Monoclonal*
;
Blood Cells*
8.A Comparative Study of Commercial Antigens and Fresh Antigens in Atopic Dermatitis and Chronic Urticaria Patients with Fish and Shellfish Antigens.
Ki Beom PARK ; Hee Chul EUN ; Yoo Shin LEE
Korean Journal of Dermatology 1987;25(1):31-40
This study was undertaken to observe the difference of patch test and prick test positive reactions in three groups, 20 atopic dermatitis patients, 20 chronic urticaria patients, and 20 normal controls, Twenty commercial antigens (ToriiCo.) and twenty three frozen and boiled antigens of fishes and shellfishes were used as test materials. The results were as follows: 1. No positive reaction was observed in all sixty subjects in patch test. 2 In prick test, difference in reactivity was observed among atopic dermatitis (14. 7%), chronic urticaria (8.7%), and normal control(1. 5%) 3. There was significant difference in reactivity between Torii and frozen antigens in atopic dermatitis group, but no significance in chronic urticaria and control groups. 4. Boiling altered the reactivity in tested materials in all three groups of subjects singificantly. 5. Patients with past or family history of allergic diseases showed double fold higher reactivity tban patients without any history.
Dermatitis, Atopic*
;
Fishes
;
Humans
;
Patch Tests
;
Shellfish*
;
Urticaria*
9.Insulin-Like Growth Factors and Their Bindign Proteins in Uterine Leiomyoma Pretreated with Gonadtropin Releasing Hormone Agonist.
Ki Chul KIM ; Jung Gu KIM ; Jin Yong LEE
Journal of Korean Society of Endocrinology 1997;12(3):364-375
BACKGROUND: Uterine leiomyoma is the most common pelvic tumor, occurring in 20-25% of women in reproductive age. Gonadotropin releasing hormone agonist (GnRHa) has been reognized as a temporary medical management for this disorder. The etiology of these tumors is unknown but it has been shown that the insulin-like growth factors (IGF-I, IGF-II) are promoters of growth in nongynecologic tumors. Several recent studies have suggested the possible role of IGFs in human leiomyoma growth. The IGF binding proteins (IGFBPs) are believed to modulate actions of IGF and to have IGF-independent actions. The purpose of this study was to evaluate the type of IGF and IGFBP which may be involved in leiomyoma growth and to investigate a possible IGF related mechanism of action of GnRHa. METHOD: The IGFs and IGFBPs were measured by double antibody radioimmunoassay, western ligand blot and immunoprecipitation in the tissue cytosols of normal uterine myometria (n=15), nontumorous myometria adjacent to a leiomyoma and leiomyoma from patients nontreated (n=15) and treated (n=10) with GnRHa. RESULTS: The mean IGF-I and IGF-II level were significantly higher in leiomyoma from untreated patients than in the adjacent myometrium and normal myometrium but no significant differences in these IGF levels between normal myometrium and adjacent myometrium were noted. The IGFBP-2, IGFBP-3 and 26kDa IGFBP were detected variably but IGFBP-4 was consistently present in all tissues. There were no significant differences in the relative intensity for IGFBP-4 and the frequency of IGFBPs between leiomyoma, adjacent myometrium and normal myometrium from untreated patients. The IGF-I, IGF-II levels and the relative intensity of IGFBP-4 in leiomyoma from GnRHa-treated patients were significantly lower than those in untreated patients, but these levels in the adjacent myometrium were comparable. The frequency of each IGFBP in leiomyoma and the adjacent myornetrium from GnRHa-treated patients did not significantly differ from untreated patients. CONCLUSION: Both IGF-I and IGF-II are involved in the growth of leiomyoma and GnRHa may in part act to decrease size of leiomyoma by regulating the local levels of IGF-I, IGF-II and IGFBP-4.
Animals
;
Cytosol
;
Female
;
Gonadotropin-Releasing Hormone
;
Humans
;
Immunoprecipitation
;
Insulin-Like Growth Factor Binding Protein 2
;
Insulin-Like Growth Factor Binding Protein 3
;
Insulin-Like Growth Factor Binding Protein 4
;
Insulin-Like Growth Factor Binding Proteins
;
Insulin-Like Growth Factor I
;
Insulin-Like Growth Factor II
;
Leiomyoma*
;
Mice
;
Myometrium
;
Radioimmunoassay
;
Somatomedins*
10.A Case of Rieger's Syndrome Associated with Controlled Glaucoma.
Soon Kuk JUNG ; Sung Ki LEE ; Bong Chul KIM
Journal of the Korean Ophthalmological Society 1995;36(5):890-895
Rieger's syndrome is a rare autosomal dominant developmental anomaly characterized by ocular and systemic abnomalities. These disorders are typically bilateral and usually diagnosed at birth or in the childhood. The most common ocular defects are hypoplasia of the iris, a prominent Schwalbe's line with iris strands and corectopia. A large number of patients have glaucoma due to devel-opmental defects of the anterior chamber angle structure. The authors experienced a case of Rieger's syndrome which was found in 31-year-old female, who had characteristic ocular and other systemic abnormalities. Associated glaucoma was well controlled by filtering surgery.
Adult
;
Anterior Chamber
;
Atrophy
;
Edema
;
Female
;
Filtering Surgery
;
Frontal Lobe
;
Glaucoma*
;
Glioblastoma
;
Humans
;
Intracranial Pressure
;
Iris
;
Neurofibromatoses
;
Optic Atrophy
;
Optic Nerve
;
Optic Nerve Diseases*
;
Parturition
;
Skin