1.Susceptibility of cockroaches (Blattella germanica Linneaus) to various insecticides.
Chul Hwan CHA ; Ki Sun HAM ; Young Il LEE ; Sung Hoi KOO ; Ryang Il HAN
The Korean Journal of Parasitology 1970;8(2):67-70
During the period from May to October 1969, the authors carried out a series of tests with the aim to ascertain the present status of susceptibility of adult cockraoches to various insecticides. The tests on the susceptibility of cockroaches to dieldrin, D.D.V.P., Diazinon; Dibrom, Malathion and lindane were performed with the topical application and the residual film methods under the conditions of 26 degrees C and 80% of relative humidity. The insects tested were collected from Seoul City and were reared at the laboratory. Some of the important results so far obtained can be summarized as follows: The median lethal doses (LD(50)) of the five insecticides against female adult cockroaches were: 0.4 ug/roach or 4.02 ug/body weight (gm) by Dieldrin, 0.29/roach or 2.88 ug/body weight (gm) by D.D.V.P., 0.29 ug/roach or 2.96 ug/body weight (gm) by Diazinon, 0.54 ug/roach or 5.37 ug/body weight (gm) by Dibrom, and 2.96 ug/roach or 29.60 ug/body weight (gm) by Malathion. And those against male adult cockroaches were: 0.18 ug/roach or 3.29 ug/body weight (gm) by Dieldrin, 0.27 ug/roach or 4.89 ug/body weight (gm) by D.D.V.P., 0.16 ug/roach or 2.91 ug/body weight (gm) by Diazinon, 0.49 ug/roach or 8.97 ug/body weight (gm) by Dibrom, and 1.32 ug/roach or 24.19 ug/body weight (gm) by Malathion. The level of susceptibility of adult cockroaches to the insecticides tested was 1.0-1.6 times higher as compared with the results obtained on the Japanese Takashi strain. The median knockdown times (LT(50)) of the female adult cockroaches by insectcides at 1% concentration of 3 mg per square centimetre were 1.82 hours by Malathion, 1.36 hours by Diazinon, 0.56 hours by Lindane, 0.50 hours by Dibrom, and 2.56 hours by D.D.V.P. A marked difference was seen to exist between the males and the females. The female cockroaches were more resistant than the male to Dieldrin, Diazinon and Malathion.
parasitology-arthropoda-cockcroach-Blattella germanica
;
chemotherapy
;
Dieldrin
;
D.D.V.P.
;
Diazinon
;
Dibrom
;
Malathion
;
lindane
;
resistance
2.The News on Moyamoya Disease: Review Article.
Ki Chul CHA ; Seung Chyul HONG
Korean Journal of Cerebrovascular Surgery 2011;13(2):59-65
Moyamoya disease is a rare idiopathic cerebrovascular disease which is known to cause ischemic or hemorrhagic strokes in association with progressive stenosis of intracranial major arteries and subsequent formation of fragile collateral vessels. In this review, we have provided an update on the epidemiology, pathophysiology, clinical presentation, diagnosis, treatment and prognosis of moyamoya disease.
Arteries
;
Constriction, Pathologic
;
Moyamoya Disease
;
Prognosis
;
Stroke
3.Segmental Bioelectrical Impedance Analysis(SBIA) for Determining Body Composition.
Ki chul CHA ; Cheong Min SHON ; Ki Jin KIM ; Seung Hoon CHOI
Korean Journal of Community Nutrition 1997;2(2):179-186
A new bioelectrical impedance method has been developed and evaluated. The electrodes; were made of stainless steel and electrical interfaces were created by an upright subject gripping hand electrodes and stepping onto foot electrodes. Eight tactile electrodes were in contact with surfaces of both hands and feet; thumb, palm and fingers, front sole, and rear sole. Automatic on-off switches were used to change current pathways and to measure voltage differences for target segments. Segmental body resistances and whole body resistance(RWHOLE)were measured in 60 healthy subjects. Segmental resistances of right arm(RRA), left arm(RLA), trunk(RT), right leg(RRL) and left leg(RLL)were310.0+/-61.6 omega, 316.9+/-64.6 omega, 25.1+/-3.4 omega, 236.8+/-31.2 omega and 237.6+/-30.4 omega, respectively. Individual segmental impedance indexes(Ht2/RRA, Ht2/RT, and Ht2 /RLA) were closely related to lean body mass(LBM)as measured by densitometry ranged from r=0.925 to 0.960. Ht2/(RRA+RT+RLA) predicted LBM slightly better(r=0.969) than the traditional index, Ht2/RWHOLE(r=0.964), supporting the accuracy of the segmental measurement. A multiple regression equation utilizing Ht2/RRA, Ht2/RT and Ht2/RRL predicted LBM with r=0.971. Ht2/RRA term of the regression contributed to more than 40% of the LBM prediction, indicating that lean mass of arm represented whole body LBM more closely than other body segments. The new bioimpedance method was characterized by upright posture, eight tactile electrodes, segmental measurements and utilization of electronic switches in comparison with the traditional method. The measurement with this new method was extremely reproducible, quick and easy to use.
Adipose Tissue
;
Arm
;
Body Composition*
;
Densitometry
;
Electric Impedance*
;
Electrodes
;
Fingers
;
Foot
;
Hand
;
Hand Strength
;
Posture
;
Stainless Steel
;
Thumb
4.Metaplastic Carcinoma of the Breast with Chondroid Calcification: A Case Report.
Byung Ki KIM ; Kyung Hwan BYUN ; Soo Yun CHUNG ; Mi Gyung YI ; Jong Yup BAE ; Chul Woon CHUNG
Journal of the Korean Radiological Society 2002;46(2):187-190
Metaplastic carcinoma is a rare form of breast carcinoma in which a variety of metaplastic changes occur. These commonly involve squamous or spindle cells, but pure chondroid metaplasia is relatively uncommon. We report a case of metaplastic carcinoma of the breast which mainly involved chondroid metaplasia and in which chondroid calcifications were seen on mammograms.
Breast Neoplasms
;
Breast*
;
Cartilage
;
Metaplasia
5.The Differential Assessment of Human Cytomegalovirus Infectivity by in Situ Polymerase Chain Reaction.
Ki Chul SHIN ; Dae Joong KIM ; Jin Hee KIM ; Chung Gyu PARK ; Eung Soo HWANG ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1999;34(4):363-372
No abstract available.
Cytomegalovirus*
;
Humans*
;
Polymerase Chain Reaction*
6.Insecticide resistance in bedbugs(Cimex lectularius) in Korea.
Chul Hwan CHA ; Ki Sun HAM ; Jong June YOON ; Jong Hwan HWANG ; Kwan Woo LEE ; Sung Hoi KOO
The Korean Journal of Parasitology 1970;8(1):5-7
In the summer of 1969 from July through October, authors carried out a study of susceptibility in adult female bed bug(Cimex lectularius) in order to ascertain any development of resistance to insecticides in Korea. The test to DDT and Dieldrin was performed in laboratory by the continuous exposure of residues method, with standard impregnated paper used for adult mosqitoes. Some results so far obtained can be summarised as follows: LC(50) were 2.839% in DDT and 0.167% in Dieldrin. The resistance has been arisen 2.4-2.9 times in DDT and 1.6-2.4 times in Dieldrin as compared with London laboratory strain, but they were susceptible 1.4 times in DDT and 180 times in Dieldrin as compared to Israel resistance strain.
parasitology-arthropodology-bed bug-Cimex lectularius
;
prevention
;
chemotherapy
;
resistance
;
DDT
;
dieldrin
7.Short Term Results of Cementless Total Hip Arthroplasty with Using a Accolade TMZF Femoral Stem.
Hyung Ku YOON ; Chang Soo AHN ; Ki Shik NAM ; Seung Chul HAN
Journal of the Korean Hip Society 2008;20(4):252-257
PURPOSE: We wanted to evaluate the short term clinical and radiological results and the complications of primary total hip arthroplasty with using a Accolade TMZF femoral stem. MATERIALS AND METHODS: 66 cases among 80 cases underwent total hip arthroplasty by one surgeon with using an Accolade TMZF femur stem from January 2002 to August 2006. The minimum follow-up was 30 months and we retrospectively analyzed these 66 patients. RESULTS: The mean Harris Hip Score improved from 54 to 92 at the last follow up. On the last follow-up X-ray, all the femoral stems (100%) showed stable fixation and there was no osteolysis or loosening, but there were 34 cases of stress shields and 20 cases of cortical hypertrophy. The acetabular component revealed stable fixation in 65 cases (98.5%) and loosening in one case (1.5%). There was no acetabular osteolysis, but 22 cases of radiolucency were observed in the Dee Lee and Charnley zone II. As complications, there were 5 cases of heterotrophic ossification, 1 case of greater trochanteric bursitis, 2 cases of thigh pain and 1 case with a squeaking sound. CONCLUSION: Primary total hip arthroplasty using a cementless Accolade TMZF femoral stem showed good results in the short term, but long term follow up is needed.
Arthroplasty
;
Bursitis
;
Femur
;
Follow-Up Studies
;
Hip
;
Hypertrophy
;
Osteolysis
;
Retrospective Studies
;
Thigh
8.Brain Magnetic Resonance Imaging(MRI) in Neurologic Disorders of Children.
Jin Hee YUN ; Jae Guk CHA ; Ki Sic MIN ; Jong Wan KIM ; Kwang Nam KIM ; Ki Yang RYOO ; Ho Chul KIM
Journal of the Korean Pediatric Society 1995;38(8):1132-1140
No abstract available.
Brain*
;
Child*
;
Humans
;
Nervous System Diseases*
9.Validation of Pre-Hospital Stroke Screens by Ambulance Service Personnel: A Prospective Observation Study.
Ki Ok AHN ; Sang Do SHIN ; Chang Bae PARK ; Kyoung Jun SONG ; Ki Jeong HONG ; Seung Chul LEE ; Sungwoo MOON ; Won Chul CHA
Journal of the Korean Society of Emergency Medicine 2013;24(3):272-278
PURPOSE: We evaluated the validity of Pre-Hospital stroke screening (PHSS) by 119 ambulance rescuers in Korea. METHODS: Patients at least 20 years old with presumed stroke were transported to six emergency medical centers and prospectively enrolled during a 12-month period. A total of 119 ambulance rescuers applied the Cincinnati Pre-Hospital Stroke Scale (CPHSS) and the Los Angeles Pre-Hospital Stroke Screen (LAPHSS). Emergency physicians (EPs) further assessed the patients with CPHSS and LAPHSS. The final diagnoses were divided into stroke and other disease categories through a review of hospital records. The sensitivity and specificity of the two screening tools were analyzed for predicting stroke. The CPHSS and LAPHSS scores from all patients were compared between the 119 ambulance rescuers and EPs. RESULTS: The 119 ambulance rescuers referred 348 suspected stroke patients, of whom 164(47.1%) had their stroke confirmed. For all kinds of stroke, the sensitivity and specificity of the CPHSS were 86.3%[95% confidence interval (CI) 58.6~76.1] and 65.9%(95% CI 57.0~74.0), respectively, and those of the LAPHSS were 70%(95% CI 61.0~78.0) and 67.8%(95% CI 58.6~76.1), respectively. The Kappa value between the 119 ambulance rescuers and EPs was k=0.619(95% CI 0.523~0.715) for the CPHSS and k=0.392(95% CI 0.275~0.510) for the LAPHSS. CONCLUSION: CPHSS and LAPSS performed by 119 ambulance rescuers had considerable validity in Korea.
Ambulances*
;
Diagnosis
;
Emergencies
;
Emergency Medical Services
;
Hospital Records
;
Humans
;
Korea
;
Mass Screening
;
Prospective Studies*
;
Sensitivity and Specificity
;
Stroke*
10.Gene Expression Analysis between Uterine Leiomyoma and Normal Myometrial Tissues by DNA Chip.
Sang Hoon KWON ; Chi Hum CHO ; Soon Do CHA ; Won Ki BACK ; Moon Kyu KIM ; Jung Chul KIM
Korean Journal of Obstetrics and Gynecology 2003;46(4):701-706
OBJECTIVE: To investigate the difference of gene expressions between leiomyoma and normal myometrial tissue was analzed by DNA Chip. METHODS: cDNAs retro-transcribed from equal quantities of mRNA derived from leiomyoma and corresponding normal myometrial tissue were labeled with Cy5 and Cy3 fluorescein as probes. The mixed probe was hybridized with two pieces of 3,066 double dot from a human dermal papilla cell cDNA library and scanned with a laser scanner. The acquired image was analyzed by ImaGene 3.0 software. Validation of gene expression was performed by reverse transcription-Polymerase chain reaction (RT-PCR) in 5 leiomyomas and corresponding normal myometrial tissues. RESULTS: Among many differentially expressed genes, genes with expression levels more than 3 times were found by comparing leiomyoma with corresponding normal myometrial tissue. One gene with expression levels lesser than 3 times in leiomyoma tissue compared to normal myometrial tissue was also detected. Although alterations of several genes, such as osteoblast specific factor 2, PAI-1 mRNA-binding protein, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase alpha subunit (HADHA), p311, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1 (DDX1), Hexokinase 1, 2 were identified in a significant high fraction of uterine leiomyoma compared to normal myometrial tissue. Cyr61 gene was shown to be markedly down-regulated in leiomyoma compared with the matched uterine myometrial control. I validated differential expression of genes by RT-PCR and demonstrated overexpression of OSF-2, HADHA, p311, DDX1, Hexokinase 1, 2. CONCLUSION: DNA chip techniques are effective in screening differential gene expression between leiomyoma tissue and normal myometrial tissue. These genes may be related to the genesis and development of uterine leiomyoma. Analysis of the human leiomyoma gene expression profile by DNA chip may be helpful gene diagnosis, treatment and prevention of this disease.
Diagnosis
;
DNA*
;
DNA, Complementary
;
Fluorescein
;
Gene Expression*
;
Gene Library
;
Hexokinase
;
Humans
;
Leiomyoma*
;
Mass Screening
;
Oligonucleotide Array Sequence Analysis*
;
Osteoblasts
;
Plasminogen Activator Inhibitor 1
;
RNA, Messenger
;
Transcriptome