1.Phenotypic evidence of ultra-highly diluted homeopathic remedies acting at gene expression level: a novel probe on experimental phage infectivity in bacteria.
Saha, Santu Kumar ; Das, Sreemanti ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(4):462-70
To explore if some ultra-highly diluted homeopathic remedies claimed to have antiviral effects can demonstrate any discernible action in the bacteria Escherichia coli through modulating infectivity potentials of the bacteriophage φX174 DNA.
2.Homeopathic Thuja 30C ameliorates benzo(a)pyrene-induced DNA damage, stress and viability of perfused lung cells of mice in vitro.
Mukherjee, Avinaba ; Boujedaini, Naoual ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2013;11(6):397-404
To examine if the ultra-highly diluted homeopathic remedy Thuja 30C can ameliorate benzo(a)pyrene (BaP)-induced DNA damage, stress and viability of perfused lung cells of Swiss albino mice in vitro.
3.Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade.
Ghosh, Samrat ; Bishayee, Kausik ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2014;12(2):102-14
Oleanolic acid (OA) has been reported to have anticancer effects, but the extent of its cytotoxicity, its ability to interact with nuclear DNA, its action against skin melanoma, as well as the molecular mechanism of its action against cell proliferation and in support of cell death are still unexplored. This led us to examine the efficacy of OA, a bioactive compound isolated from Phytolacca decandra, on these issues in the present investigation.
4.Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo.
Ghosh, Samrat ; Sikdar, Sourav ; Mukherjee, Avinaba ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2015;13(1):34-44
Chemopreventive approach with natural products, particularly plants and plant-derived ones, is receiving increasing attention for their effective role against cancer without any palpable side effects. In this study, efficacy of ethanolic extract of Ruta graveolens (RG) on skin melanoma cells (A375) in vitro and on 7,12-dimethylbenz(a)anthracene (DMBA)-induced skin cancer in vivo has been tested in Swiss albino mice.
5.Potentized homeopathic drug Arsenicum Album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate.
Das, Durba ; De, Arnab ; Dutta, Suman ; Biswas, Raktim ; Boujedaini, Naoual ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2011;9(7):752-60
This study examines if homeopathic drug Arsenicum Album 30C (Ars Alb 30C) can elicit ameliorative responses in yeast (Saccharomyces cerevisiae) exposed to arsenate.
6.Analysis of the capability of ultra-highly diluted glucose to increase glucose uptake in arsenite-stressed bacteria Escherichia coli.
Khuda-Bukhsh, Anisur Rahman ; De, Arnab ; Das, Durba ; Dutta, Suman ; Boujedaini, Naoual
Journal of Integrative Medicine 2011;9(8):901-12
Whether ultra-highly diluted homeopathic remedies can affect living systems is questionable. Therefore, this study sees value in the analysis of whether homeopathically diluted glucose 30C has any effect on Escherichia coli exposed to arsenite stress.
7.Potentized homeopathic drug Arsenicum Album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenine-exposed bacteria Escherichia coli.
De, Arnab ; Das, Durba ; Dutta, Suman ; Chakraborty, Debrup ; Boujedaini, Naoual ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(2):210-27
To examine if potentized homeopathic drug Arsenicum Album 30C (Ars Alb 30C) can reduce sodium arsenite-induced toxicity in Escherichia coli.
8.Anticancer potentials of root extract of Polygala senega against benzoapyrene-induced lung cancer in mice.
Paul, Saili ; Bhattacharyya, Soumya Sundar ; Samaddar, Asmita ; Boujedaini, Naoual ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2011;9(3):320-7
To evaluate anticancer potentials of Polygala senega on lung cancer induced by benzo[a]pyrene (B[a]P) in mice.
9.Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes.
Das, Sreemanti ; Saha, Santu Kumar ; De, Arnab ; Das, Durba ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(3):337-46
To examine to what degree an ultra-highly diluted homeopathic remedy, Arnica Montana 30C (AM-30C), used in the treatment of shock and injury, can modulate the expression of nucleotide excision repair genes in Escherichia coli exposed to ultraviolet (UV) irradiation.
10.Ameliorative potentials of Syzygium jambolanum extract against arsenic-induced stress in L6 cells in vitro.
Samadder, Asmita ; Das, Jayeeta ; Das, Sreemanti ; Biswas, Raktim ; Khuda-Bukhsh, Anisur Rahman
Journal of Integrative Medicine 2012;10(11):1293-302
To determine the ameliorative potentials of Syzygium jambolanum (SJ) extract in L6 skeletal muscle cells in regard to arsenic-induced impairment of optimum glucose homeostasis and improper functioning of mitochondria.