175 Basedow’s disease patients (45 males and 170 females; mean age: 44.48 ± 8.89) were treated by I-131 at Bach Mai hospital and Military Hospital 103. Total T3 level in serum was 6.45 ± 2.81 nmol/l (n=146) and total T4 level was 243.58 ± 72.34 nmol/l (n=143). Before treatment T3 and T4 level increased abnormaly comparing with healthy people. By 4 months of treatment, T3 level was 2.15 ± 0.78 nmol/l and T4 level was 120.35 ± 36.81nmol/l, FT4 level was 15.67 ± 6.51pmol/l. With average dose of 6.52 ± 1.64 mCi I-131, most of patients had normalized total T3, T4 level
Graves Disease ; Therapeutics

Growth hormone (GH) concentration in the blood of healthy adult was measured by RIA (radioimmunoassay) method. The results are as follow: Concentration of GH in the blood of male is lower than in female(p<0.05). There is no significant difference in concentrations of GH at 8-10 AM and 6-9 PM.
Hormones ; Radioimmunoassay

A study on the healthy voluntary adults without acute or chronic thyroid diseases, with ages of 21-48 who lived in Hanoi, Hai phong and HoChi Minh city has shown that there were no differences of total T3, T4 and FT3, FT4, TSH in the morning, noon and afternoon and there were no significant difference of these between men and women in each region and between regions.
Hormones ; Receptors, Thyrotropin ; Thyroid Hormones

An evaluation of image and weight of the thyroid in patients with the basedow by scintigraphy has shown that there were no significant changes of length of right and left lobe of thyroid between age groups of patients with basedow. The weight of thyroid calculated as formula of Goodwill were more than these calculated as formula of Okubo and these in men were more than in women. The size and weight of thyroid in patients with basedow were more than these in normal people.
Thyroid Gland ; Graves Disease

98 patients with Basedow disease were treated by I-131 at Department of Nuclear Medicine, Bach Mai Hospital. The results are as follow: after 7-9 years of I-131 therapy, no recurrence was reported in 100% patients. Incidence of hypothyroidism after 1 year is 4.0%. Accumulated incidence of hypothyroidism in every year is 1.75%. This incidence is lower than that of foreign authors. The treatment of patients with Basedow disease by I-131 in Vietnam is safe, economic and simple method.
Hypothyroidism ; Graves Disease ; therapeutics ; Pharmaceutical Preparations

Serum TRAb concentration in healthy and Basedow patients before and after I-131 treatment was measured by RIA (Radioimmunoassay) method. The results were as follows: We standardized RIA method for measuring TRAb. Serum TRAb concentration in healthy adults (n=20) was at undetectable level. Serum TRAb concentration in the Basedow patients before I-131 treatment was 326.98+/-206.21mM/ml (n=20), which are hundreds times higher in comparison with normal people. After I-131 treatment: 5/12 Basedow patients have TRAb concentrations in the threshold of indefectibility and in 7/12 patients were 127.67+/-59.21 mU/ml, lower than before treatment.
Graves Disease ; Antibodies ; serum ; adult ; therapeutics

TRAb concentration in the blood of healthy adults and Basedow patients before and after I-131 treatment was measured by RIA (Radioimmunoassay) method. The results were as follow: RIA method for measuring TRAb was standardized. TRAb concentration in the blood of healthy adults was in the very low level (undetectable). TRAb concentrations in the Basedow patients before I-131 treatment were 426.98+/-206.21 mU/ml and by many times higher than that of healthy adults. After I-131 treatment: TRAb concentrations in the 5/12 Basedow patients could not be measured (undetectable) and in 7/12 patients were 127.67+/-59.21 mU/ml.
Graves Disease ; Antibodies ; blood

Thyroid ultrasound was used to measure thyroid volume in patients with Basedow before and after treating by I-131. The results were as follow: after treatment of I-131 (from 2 to 16 months, average dose: 6.3+/-1.14 mCi), the thyroid volume of all most these patients decreased clearly in comparison with before treatment. Decreased average rate was 60.5%.
Thyroid Gland ; Graves Disease ; therapeutics ; drug therapy

The authors used ultrasonic machine with 7.5 MHz probe and scintigraphic scanner to evaluate the reduction of thyroid volume in Basedow patients treating with I-131 (average dose: 6,3 (1.14mCi). The results are as follow: After treatment 2-16 months, thyroid volume was reduced 67.7% (measurement by ultrasonography) and 72.5% (measurement by scintigraphy), comparing with this before treatment.
Ultrasonography ; Graves Disease ; Radionuclide Imaging

The volumes of thyroid of 133 patients with basedow were determined. The results have shown that the volume of thyroid measured by ultrasound was 39,18+/- 19,02 ml and by hand was 37,18 +/- 9,04 ml. The weights of thyroid measured by scintigraphy were different as formulation of calculation. The results calculated by formulation of Okubo were the same as these by ultrasound and by hand.
Ultrasonography ; Graves Disease ; Radionuclide Imaging ; hand