There were currently diagnosed by totally 177 cases with HIV in our country. The 82.3% of those were male and 72.9% of them were men sex with man. Sexual minority group especially men who intercourse with male are highly risk to HIV infection. By the study of 2011, which aimedto assess risk to exposure HIV infection among sexual minority group, 56.2% of all participants answered as had depression symptoms and 12.8% of them seen to psychologist and health workers. In addition, 2% of them used by injection of drug for last year, and 60.6% harmfully drank.The study was done by quantitative and qualitative methods and used specific designed questionnaire for sexual minority with HIV infection. Totally 26 consumers participated in our survey. Before the starting of the study, we introduced inform consent to all participants and if they agreed to participate, we coded research cards and collected the information.All participants were answered alcohol drink, and 46.1% of them determined with heavy drinking or harmful consumption by the AUDIT versus 7.8% were alcohol dependence. 65.3% oftotal participants used as smoke, 5 cases used cannabis; one of them has been used within last twelve months. In addition, 23.1% of all participants had anxiety and 15.3% had mild depression symptoms. Of the total 26 cases, 7 cases had suicide thinking related with sexual orientationand 2 cases had suicide thinking related with HIV infection. Those cases answered often feeling hopeless and helpless.In sexual minority group with HIV, alcohol and tobacco consumption was high, drug abuse was low. 15.3-23.1% of all participants had depression and anxiety symptoms. Suicide thinking has been occurred for those cases it means risk to suicide commitment.