WHO issued the guidance for evaluation of the safety and validity of herbal medicine including the qualitative standards of materials, and preparations (fresh and dry materials, processed materials, storage, package and labeling), and general researches on the pharmaceutical and pharmacological aspects (toxicity, grow, and materials development).
Plants ; Plants, Medicinal

This paper introduced the WHO guideline on the research on the medicinal plants including the overview of research on the medicinal plant, method of study, qualitative standard of medicinal plant, preparation and reference, on the pharmacokinetic, pharmacological, preclinical, clinical studies
Plants, Medicinal ; Guideline [Publication Type] ; pharmacokinetics

In East Mediterranean countries, in Oman islamic country up to the year 1995, in Saudi Arabia there are some regulations for traditional medicaments. From November 1993, in Argentina, regulation concerning the registration and the trade of traditional medicines were promulgated, pursuant this, the traditional preparations must be registered within 180 days. In Canada, medicinal herbal, as medicines must be in compliance of the rules of labeling and other rules of the Law of Foods and Drugs. American Law regulates the labeling as for food additives – WHO survey noted on the administration of traditional medicine only in Mali, Mauritania and South Africa
Medicine, Traditional ; Public Policy ; Case Management

The clinical results, expert's opinions are reported. Among 200 studied drug products, 91 products haven't new effects, 33 drugs have suspected effects or no effect, 7 drugs aren't trust and may be dangerous. On the other hand, drug's price are increasing, it raised median 5.3% a year in 1990 and raised to 8.9% a year in 2000. In fact, countries deal with this problem by steps including 9 steps reported this article
Pharmaceutical Preparations ; Pharmacy ; Expert Testimony ; drugs ; Commerce

Antibiotics were studied and has been used for a long time, and this medicine more and more develops and renovates. Antibiotics were renovated and classified. According to current definition, antibiotics are all natural mixes, semi-collection or collection with antibacterial effect. According to this definition, antibiotic is classified: Antibiotic is natural mix (including six main groups); semi-collective antibiotic, collective antibiotic. Changes in each antibiotic group has been studied. Authors also investgated collective antibiotic in this topic. In addition, main problems are currently solved: toxicity and allergy of some antibiotics, antibiotic resistance, probability happening when using mixture of many antibiotics (via simple combining effect or antagonistic effect)
Anti-Bacterial Agents ; Pharmaceutical Preparations

Translate summarily overview document about traditional drug program of WHO (1998) which named: “ actual situation of adjust medicinal herbs” and concentrate to nearly areas and countries which are Vietnam’s partners. Include: development of traditional medicine in Australian, China, Macao, Fiji, Japan, real situation of management traditional drug in Mongolia, New Zealand, Philippines, Singapore, Korea and Vietnam.
Medicine, Traditional ; Public Policy ; Case Management

Polyphenols and flavonoides from Momordica charantia are able to inhibite activities of enzymes catalase and peroxiadase strongly. Preparations are extracted from fruit whose are stronger and the strongest inhibition are flavonoid of fruit Momordica charantia. Polyphenols and flavonoide of Momordia charantia are different effects to peroxidase of Jour blood grounds of human serum. All most preparations are able to inhibit very strongly to peroxidase in serum of group AB from human blood, such as: Polyphenol of fruits AB > O > A >B, Polyphenol of leaves AB > A >B>O, Flavonoide of fruits AB > A >O>B, Flavonoide of leaves AB > A >O>B. Flavonoide of fruits and leaves make decrease Glucose of Cavy blood whithin six hour Cavy drank preparations. In which flavonoids of leaves decrease 15% and flavonoids from fruits do 30%. Preparation extracted from fruits and leaves of Mormordica charantia have anti bacterials. Especially flavonoids extracted from fruits have anti bacterial stronger, but they have a better fungistatic and all most have anti yeast.
Momordica ; polyphenols ; flavonoids ; Plants, Medicinal

The flavonoids from papaya leaves have the selective action on the cells. It destroyed cancer cells Hep-2, but don't make any bad influence to the normal lymphocyte. In addition, The obtained flavonoids have mitogenic activity on the lymphocyte of human. Flavonoids of papaya leaves have different effect on the inhibition of the growth and development of bacteria
Biological Therapy ; flavonoids ; microbiology ; Plants, Medicinal

The pholyphenols in Abutilon indicum are soluble in methanol, ethanol, distilled water, and in acid medium. Abutilon indicum contained components of the natural substances such as: amino acids, aliphatic compounds, sugars, polyphenols, flavonoids, alkaloids, glucosids. Content of polyphenols in Abutilon indicum were very high (16.92-28.62 mg/g), in which flavonoids of Abutilon indicum are various and distributed in trunk, roots and fruits, with characteristic components having absorption at 270-290 nm(flavonon).
Plants, Medicinal ; Medicine, Traditional

The Lectin from Nulumbo nucifera and Telosma cordata have been extracted and purified by following process: Extraction with suitable medium precipitation with Ammoniumsunphate or Ethanol - ion exchange chromatography on CM-Cellulose of DEAE-Cellulose. Preparations having high purity showed homogeneous proteins in SDS-polyacrylamide gel-electrophoresis. pH-Optimum of the lectins from Nelumbo nucifera is pH 8.3, but form Telosma cordata is pH 5.5. The potency order of agglutination with monosaccharides was as Fructose, NAc-Glucosamine, Arabinose and NAc-acid Neuraminic for Nelumbo nucifera, but the lectin from Telosma cordata was inhibited only by Fructose, Saccharose NAc acid neuraminic. The lectins from Nelumbo nucifera and Telosma cordata were inhibited by many proteins from original Animals
Lectins ; Lotus ; Plants, Medicinal ; Medicine, Traditional