A study on the coagulation changes in 31 patients with moderate acute hepatitis B in the Army Central hospital 108 and the Institute of Clinical Medicine and Tropical diseases has shown that activated partial thromboplastin time (APTT) was prolonged, the prothrombin rate and the coagulant factors of II,VII and X were moderately reduced during stage of complete crisis and reversed during remission stage. The coagulant factor V was not be influenced. Number of thrombocyte and concentrations of compounds FDF, D-dimer from decomposition of fibrin/fibrinogen was normal.
Hepatitis ; Blood Coagulation

A study on the 11 patients (male: 8; female:3) in the Army Central hospital 108 and the Institute of the Clinical Medicine and Tropical diseases with clinical diagnosed as malignant hepatitis B has shown that the the clinical symptoms were nausea, vomiting, tired, weakness, coma, skin haemorrhage, internal haemorrhage, hepatic contraction. This is the first time of hepatitis B for all 11 patients. The hepatic functional tests and viral marker in 11 patients expressed the syndrome of the disseminated intravascular coagulation. The coagulation factors were significantly reduced related with hepatocellular damage level and disease’s status
Hepatitis B ; Disseminated Intravascular Coagulation