1.Chronic pain and emotional disorders as well as the effect of interventional treatment
Kezhen BAI ; Huquan YANG ; Zufang HUANG ; Ke GONG ; Bo QU ; Shitao WU
Chinese Journal of Tissue Engineering Research 2006;10(6):190-192
OBJECTIVE: To analyze the relationship between chronic pain and painprone meutal disorders and investigate the effect of psychological intervention and medication.DATA SOURCES: Related literatures about the relationship between chronic pain and pain-prone mental disorders were searched on computer in Medline and Embase from January 1989 to May 2004 with the retrieval word of "Chronic pain, emotional disorder, treatment", the language was limited to English. The subjects were patients who suffered from chronic pain for above 6 months.STUDY SELECTION: Related literatures about the relationship between chronic pain and pain-prone mental disorders and its therapeutic interventions were carried on primary trial to delete those obsolete and repetitive literatures, and the others were used to search in the full text. The quality was appraised mainly on the basis of the data authenticity, preciseness of the designation, strictness of the implementation and reasonability of the statistical analysis.DATA EXTRACTION: Altogether 20 literatures were obtained and 11literatures were proved accordant with the inclusion standard. 9 literatures were excluded because 7 were repetitive experiments and two were Meta analyses.DATA SYNTHESIS: 11 literatures include experimental group and control group, patients in the experimental group were treated with analgetic combined with psychological intervention and antidepressant while those in the control group were only given analgetic; the outcomes of the two groups were compared.CONCLUSION: Chronic pain may co-exist with emotional disorders. It can be remarkably alleviated by the administration of analgetic combined with psychological intervention and antidepressant, which proves better than single analgetic medication.
2.System evaluation on Ginkgo Biloba extract in the treatment of acute cerebral infarction.
Lin WANG ; Tao ZHANG ; Kezhen BAI
Journal of Central South University(Medical Sciences) 2015;40(10):1096-1102
OBJECTIVE:
To evaluate the effect and safety of Ginkgo Biloba extract on the treatment of acute cerebral infarction.
METHODS:
The Database of Wanfang, China National Knowledge Infrastructure (CNKI) and VIPU were screened for literatures regarding Ginkgo Biloba extract in the treatment of acute cerebral infarction, including the clinical randomized controlled trials. Meta-analysis based on the Revman 4.2 system was performed.
RESULTS:
Compared with the control group, treatment with Ginkgo Biloba extract enhanced efficacy in the treatment of acute cerebral infarction (OR: 1.60-5.53), which displayed an improved neural function defect score [WMD -3.12 (95%CI: -3.96- -2.28)].
CONCLUSION
Ginkgo Biloba extract is beneficial to the improvement of neurological function in patients with acute cerebral infarction and it is safe for patients.
Cerebral Infarction
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drug therapy
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Ginkgo biloba
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chemistry
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Humans
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Phytotherapy
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Plant Extracts
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therapeutic use
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Randomized Controlled Trials as Topic