1.Computer-aided detection of pulmonary tuberculosis and pulmonary cavity on adult chest radiographs using a region convolutional neural network.
Journal of the Philippine Medical Association 2020;99(1):10-21
OBJECTIVES:
To train and evaluate the performance
of a detector for pulmonary tuberculosis and
pulmonary cavity, using the Faster Region
Convolutional Neural Network model.
STUDY DESIGN:
A cross-sectional study design was
employed to describe the sensitivity, specificity, and
accuracy of the Faster Region Convolutional Neural
Network model for the detection of pulmonary
tuberculosis and pulmonary cavity.
SUBJECTS:
Radiographs for the training dataset and
testing dataset were acquired from the Picture
Archiving and Communication System of the a
general public hospital in Quezon City.
SETTING:
The setting of the study is a general public
hospital in Quezon City, Philippines.
OUTCOMES:
The detector for pulmonary tuberculosis
and pulmonary cavity was trained with the training
dataset using the TensorFlow machine learning
library, with the Faster-RCNN-lnception-V2 used as
the base model.
Detector findings on the testing dataset were
compared and analyzed against findings of three
board-certified radiologists.
RESULTS:
The detector achieved 92.11 % sensitivity,
87.1 % specificity, and 89% accuracy as a screening
tool, and 84.04% sensitivity, 98.04% specificity, and
95.87% accuracy, as a locator of pulmonary
tuberculosis and cavity.
CONCLUSION
This study is the first of its kind to
demonstrate the feasibility of training a detector for
pulmonary tuberculosis and pulmonary cavities
using the Region Convolutional Neural Network
model. Limitations and improvements to the
detector may be addressed in future research.
Tuberculosis, Pulmonary
;
Sensitivity and Specificity
;
Neural Networks (Computer)
;
Software