1.A Case of Primary Cutaneous CD30(Ki-1)-positive Large Cell Lymphoma Showing Repetitive Spontaneous Regression and Recurrences.
Bong Kil LEE ; Ji Won KIM ; Suk Keung LEE ; Won Woo LEE
Annals of Dermatology 1999;11(2):101-105
Primary cutaneous CD30+ large cell lymphoma(LCL) is a rare cutaneous peripheral T cell lymphoma with a favorable prognosis. This lymphoma characteristically presents itself as a solitary or localized skin tumor with frequent cutaneous relapses and partial or complete spontaneous remission. Recently we saw a sixty-three year old male who had developed primary cutaneous CD30+ large cell lymphoma that waxed and waned. He presented with localized multiple nodules that had shown repetitive spontaneous regression and recurrences with the same morphology in the same area for several years. There was no evidence of nodal and visceral involvement. The immunohistochemical studies demonstrated that most neoplastic cells in the tumor were positive for CD30 and pan-T cells and negative for pan-B cells, S-100 proteins, EMA and monocyte-macrophage related antigen(CD68).
Humans
;
Lymphoma*
;
Lymphoma, T-Cell, Peripheral
;
Male
;
Prognosis
;
Recurrence*
;
Remission, Spontaneous
;
S100 Proteins
;
Skin
2.A Clinical Study of the Tibial Condylar Fracture
Soo Kil KIM ; Keung Bae LEE ; Sae Jung OH ; Young Woo KIM
The Journal of the Korean Orthopaedic Association 1987;22(5):1014-1023
The tibial condylar fracture is a fracture of the proximal end of the tibia, involving the srticular surface. This fracture frequently accompanied by soft tissue injuries such as collateral ligsment, cruciate ligament and menisci. Thirty cases of the tibial condylar fracture which treated Inchon Choong Ang Gill Hospital during the period from March, 1983 to February, 1986, the thirty cases could be followed for one year to four years. They have been analyzed according to its cause, classification, treatment and result. Among these 12 cases(40.0%) were treated by cast immobilization, 1 case(3.3%) by skeletal traction, 17 cases(56.7%) by open reduction and internal fixation. Twenty-three cases(76.7%) out of thirty revealed the rating of ACCEPTABLE according to Hohl and Lucks criteria.
Animals
;
Classification
;
Clinical Study
;
Gills
;
Immobilization
;
Incheon
;
Ligaments
;
Soft Tissue Injuries
;
Tibia
;
Traction
3.Clinical Investigation of Isolated Chest Injury.
Keung Moo LEE ; Dong Soo KIM ; Lee Suk WOO ; Hoon KIM
Journal of the Korean Society of Traumatology 2006;19(1):35-40
PURPOSE: Injuries are the third leading cause of death in Korea. Isolated chest injury is not uncommon and shows high mortality and morbidity. Several scoring systems are used for triage and stratification for trauma patients, but no standard system is accepted. We aimed to analyze the accuracy of identification of isolated chest injury by using several scoring systems. METHODS: We reviewed a total of 75 patients admitted with isolated chest injury between January 2005 and October 2005. Medical records were reviewed by using the Injury Severity Score (ISS), the Revised Trauma Score (RTS), and the Trauma and Injury Severity Score (TRISS). The scoring systems were compared by using statistics methods. RESULTS: The overall predictive accuracy of the TRISS was 12.5%, 12.0% greater than those of the RTS and the ISS. By using the area under the receiver operating characteristic (AUROC) curve, the TRISS showed an excellent discriminative power (AUROC 0.931) compared to the ISS (AUROC 0.926) and the RTS (AUROC 0.872). CONCLUSION: Compared with the RTS and the ISS, the TRISS is an easily applied tool with excellent prognostic abilities for isolated chest trauma patients. However, the TRISS, the ISS, and the RTS showed high specificity and low sensitivity, so another scoring system is required for triage and stratification of isolated chest injury patients.
Cause of Death
;
Humans
;
Injury Severity Score
;
Korea
;
Medical Records
;
Mortality
;
ROC Curve
;
Sensitivity and Specificity
;
Thoracic Injuries*
;
Thorax*
;
Triage
4.Spectrophotometric analysis of the influence of metal substrate on the color of ceramic.
Su Ok LEE ; Yi Hyung WOO ; Dae Gyun CHOI ; Keung Rok KWON
The Journal of Korean Academy of Prosthodontics 2003;41(2):148-159
STATEMENT OF PROBLEM: Metal-ceramic restorations have been used extensively by dental clinicians for nearly 40 years. Strength an functional ability of metal-ceramic restorations are proved to be satisfying, However esthetics and biocompatibility of metal alloy which is used in metal-ceramic restoration is not ideal. Using pure gold as an alternative, have advantage of esthetics, biocompatibility over conventional metal alloy. But there had been little article which studied on the color effect of pure gold on final porcelain color. PURPOSE: The purpose of this study was to spectrophotometrically evaluate the difference between color of metal alloy(Au-Pt, Ni-Cr) and pure gold, during color masking procedure with opaque porcelain and to analyze the differences. MATERIAL AND METHODS: Three types of metal-base metal(Ni-Cr), high gold alloy(Au-Pt), pure gold(GES)-specimen were fabricated 1cm in diameter. Four steps were established-after finishing, after pre-coditioning, after application of first opaque porcelain(0.08mm in thickness), after application of second opaque porcelain(0.15mm in thickness)- and tested color with spectrophotometer every each steps and analyzed with CIEL* a* b* color order system. One-Way ANOVA test was used to find out if there were significant differences between groups tested and Shaffe multiple comparison was used to identify where the differences were. RESULTS: 1. After finishing and pre-conditioning, pure gold(GES) group showed most high values in L*, a*, b*. 2. After application of first opaque porcelain(0.08mm in thickness), after appllication of second opaque porcelain(0.15mm in thickness), pure gold(GES) group showed the least difference in L*, a*, b* values and the lowest .E value(.E=0.63). 3. After application of first opaque porcelain and after application of second opaque porcelain differences that were significant (P< 0.05) between groups were found only in a values. 4. Base metal alloy group showed the lowest a value in test after application of first opaque porcelain and the highest value in test after application of first opaque porcelain. CONCLUSION: Pure gold group and high gold group showed higher a values than base metal group when tested after 0.08mm thickness of opaque porcelain was applied and pure gold group showed much similar L*, a*, b* values between 0.08mm thickness and 0.15mm thickness of opaque porcelain. This meant that pure gold was more easily masked by opaque porcelain than the other two groups.
Alloys
;
Ceramics*
;
Dental Porcelain
;
Esthetics
;
Masks
5.Huge Thoracolumbar Extradural Arachnoid Cyst.
Dong Youp LEE ; Keung Nyun KIM ; Do Heum YOON ; Seung Woo PARK
Journal of Korean Neurosurgical Society 2003;34(6):593-596
A case is presented to demonstrate the image findings of a patient with a recent onset of progressive spinal cord compression caused by a huge arachnoid cyst. A 45-year-old woman with progressive paraparesis and dysaesthesia on both legs had extradural mass on thoracolumbar junction and she was cured successfully with surgery. The tumor mass turned out to be arachnoid cyst histologically. By the time of discharge all neurologic deficits and symptoms were cured. Thoracolumbar extradural arachnoid cyst is rare cause of the spastic paraparesis. It is an unusual expanding lesion in the spinal canal which may communicate with the subarachnoid space. The goal of surgery is to decompress the spinal cord and close the connection with the subarachnoid space. We report a case of huge thoracolumbar arachnoid cyst presenting spastic paraparesis with a review of literatures.
Arachnoid*
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Female
;
Humans
;
Leg
;
Middle Aged
;
Neurologic Manifestations
;
Paraparesis
;
Paraparesis, Spastic
;
Spinal Canal
;
Spinal Cord
;
Spinal Cord Compression
;
Subarachnoid Space
6.Two Cases of Cerebral Toxoplasmosis in AIDS Patients.
Jin Hee HONG ; Young Keun CHOI ; Young Min KIM ; Jae Seung LEE ; Woo Chul LEE ; Ho Jin SHIN ; Keung Su SEO ; Ju Sup JUNG ; Goon Jae CHO
Korean Journal of Medicine 1998;55(3):400-404
Toxoplasmosis of the central nervous system occurs in 3 to 40 percent of all patients with the acquired immunodeficiency syndrome (AIDS), and it is the most common opportunistic infection to cause encephalitis or focal intracerebral lesions. We experienced two cases of cerebral toxoplasmosis in AIDS patients presenting as high fever, seizure and general weakness.
Acquired Immunodeficiency Syndrome
;
Central Nervous System
;
Encephalitis
;
Fever
;
Humans
;
Opportunistic Infections
;
Seizures
;
Toxoplasmosis
;
Toxoplasmosis, Cerebral*
7.The Changes of Arterial Ketone Body Ratio and Osmolal Gap during Hemorrhagic Shock in Rabbit.
Ill Hwan KIM ; Keung Woo LEE ; Young Kyun CHOI ; Young Jae KIM ; Jin Yoo PARK ; Chee Mahn SHIN ; Ju Yuel PARK
Korean Journal of Anesthesiology 1994;27(5):421-427
The ratio of acetoacetate to 8-hydroxybutyrate (ketone body ratio) in the blood may reflects the mitochondrial free NAD+/NADH ratio in the liver. Also arterial ketone body ratio will reflects the energy status of the hepatocytes, because mitochondrial free NAD+/NADH ratio is closely related to oxidative phosphorylation. Arterial ketone body ratio and osmolal gap, the difference between measured osmolality and calculated osmolality, were measured 30 min after the induction of hemorrhagic shock with mean arterial blood pressure at 40 mmHg in ten rabbits. Arterial ketone body ratios decreased significantly (p<0.05) from 0.74+/-0.17 to 0.38+/-0.09 and osmolal gap increased significantly (p<0.05) from 17.7+/-5.9 mOsm/Kg to 32.8+/-12.3 mOsm/Kg at 30 min after the induction of hemorrhagic shock. These results suggest that in hemorrhagic shock, decreased arterial ketone body ratio which reflects the inhibition of the TCA cycle is associated with increase of osmolal gap.
Arterial Pressure
;
Hepatocytes
;
Liver
;
Osmolar Concentration
;
Oxidative Phosphorylation
;
Rabbits
;
Shock, Hemorrhagic*
8.Effect of a traditional korean very-low-calorie diet on obese patients.
Won Il PARK ; Jong Hyup LEE ; Shim Hyun JO ; Bong Luck PAIK ; Chung Keung CHOI ; Seung Geun LEE ; Han Kyu MOON ; Young Mee CHOI ; Yoon Sok JUNG ; Kwan Woo LEE ; Hyeon Man KIM ; Mi Kyung KIM ; Ji Hyun LEE ; Sun Jeung CHOI
Korean Journal of Medicine 2002;62(3):250-257
BACKGROUND: There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effects and safety of a traditional Korean very-low-calory diet. METHODS: Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. RESULTS: Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p<0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166 mg/dL, HDL-cholesterol from 42 mg/dL, to 35 mg/dL, triglyceride from 158 mg/dL, to 75 mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205 micro International-Unit/mL x 2hr to 168 micro International-Unit/mL x 2hr (p<0.05). CONCLUSION: Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients.
Adipose Tissue
;
Body Height
;
Body Weight
;
Busan
;
Caloric Restriction
;
Cholesterol
;
Diet*
;
Humans
;
Insulin
;
Insulin Resistance
;
Intra-Abdominal Fat
;
Minerals
;
Subcutaneous Fat
;
Triglycerides
;
Weight Loss
9.Prediction of head-up tilt test result in patients with syncope of unknown origin.
Eun A CHUNG ; Seung Hyun LEE ; Young Joon HONG ; Ok Young PARK ; Woo Kon JEONG ; Sang Rok LEE ; Sang Hyun LEE ; Kyung Tae KANG ; Jay Young RHEW ; Jong Cheol PARK ; Young Keung AHN ; Myung Ho JEONG ; Jeong Gwan CHO ; Jong Chun PARK ; Jung Chaee KANG
Korean Journal of Medicine 2001;61(2):133-140
BACKGROUND: Vasovagal syncope has been believed to account for the majority of syncope of unknown origin (SUO). Head-up tilt test (HUT) has been well recognized as a useful test in the evaluation of SUO. The purpose of this study was to determine the predictors of HUT to develop a less time-consuming test protocol and get an information on the pathophysiology of vasovagal syncope. METHODS: Eighty five patients (mean age, 43+/-18 years: 47 men, 38 women) underwent a 80 degree HUT without or with isoproterenol infusion (2 migcrogram/min and 5 migcrogram/min, each for 6 minutes) for unexplained syncope or pre-syncope. Positive HUT was defined as symptomatic hypotension (systolic blood pressure < or = 80 mm Hg) and/or symptomatic bradycardia (< or = 45/min for > or = 10 seconds) or asystole > or = 3 seconds. The patients were divided into two groups according to the result of the HUT: Group I included 47 patients (M:F=25:22) with positive result, Group II, 38 patients (M:F=22:16) with negative result. RESULTS: Group I patients had more episodes of syncope than Group II (3.1+/-2.5/year vs. 2.0+/-2.1/year, p<0.05). There were no significant differences between the 2 groups in the heart rate (HR), systolic and diastolic blood pressure (BP) at the baseline supine position. BP after tilt was not significantly different between 2 groups except for systolic BP at 6 minutes after tilt, which was significantly lower in Group I than Group II (109.5+/-17.5 mm Hg vs. 118.1+/-18.2 mm Hg, p<0.05).However, HR after tilt was significantly faster in Group I than Group II (81.1+/-15.1/min vs. 74.2+/-14.9/min, p<0.05 at 2 minutes after tilt; 83.7+/-14.4/min vs. 74.6+/-14.7/min, p<0.01 at 4 minutes after tilt). The increase in HR was greater in Group I than Group II (19.9+/-12.6/min vs. 12.8+/-10.6/min, p<0.001). In the prediction of positive HUT with HR rise above 14/min during the early 6 minute of baseline head-up tilting, the specificity, sensitivity, and positive predictive value were 63.2%, 70.2%, and 70.2%, respectively. CONCLUSION: In patients with SUO, positive HUT can be predicted with the early HR response during head-up tilt. This result shows that vasovagal syncope is triggered by exaggerated HR response to the decreased venous return and allow us to develop a less time-consuming HUT protocol.
Blood Pressure
;
Bradycardia
;
Heart Arrest
;
Heart Rate
;
Humans
;
Hypotension
;
Isoproterenol
;
Male
;
Sensitivity and Specificity
;
Supine Position
;
Syncope*
;
Syncope, Vasovagal