1.Comparison of Emotional and Psychological Characteristics between Suicide Attempters and Non-Attempters in Depressed Patients : Using MMPI-2 Profiles.
Seul Ah LEE ; Keun Hyang KIM ; Shin Young SUH
Korean Journal of Psychosomatic Medicine 2012;20(1):40-49
OBJECTIVES: To examine emotional and psychological characteristics associated with suicide attempts in depressed patients. METHODS: A sample of 37 inpatients diagnosed with major depressive disorder or depressive disorder NOS was divided into two groups : lifetime suicide attempters(N=15 ; 40.54%), non-attempters(N=22 ; 59.46%). Beck Depression Scale(BDI), Beck Anxiety Scale(BAI), Hamilton Depression Rating Scale(HDRS), Hamilton Anxiety Rating Scale(HARS), and MMPI-2 were used to evaluate symptoms severity and psychological characteristics. RESULTS: Suicide attempters scored higher on the BDI though there were no group differences on the HDRS and on the both anxiety scales. Also they showed higher scores on the F, Fb, Pa, RC1, DEP, HEA, PK, AAS among MMPI-2 subscales. Our findings suggest that suicide attempters among depressed patients undergo more severe subjective distress and difficulties in adjustment than non-attempters. Also they were more hostile to others and showed lower trust. Lastly, they showed more somatic complaints and substance related problems. CONCLUSION: The present study showed that suicide attempters among depressed patients have distinct emotional and psychological characteristics. MMPI-2 would be helpful to assess suicidal risk of depressed patients.
Anxiety
;
Depression
;
Depressive Disorder
;
Depressive Disorder, Major
;
Humans
;
Inpatients
;
Pyrrolidines
;
Suicide
;
Weights and Measures
2.Expression of Cellular Oncogenes in Colorectal Cancer : c-myc, c-Ha-ras and c-erbB-2.
Hae Hyeon SUH ; Keun Nam SHIN ; Young Jin KIM
Journal of the Korean Surgical Society 1998;54(Suppl):983-990
Although causative factors are not completely defined, carcinogenesis of colorectal cancer is attributed to multiple genetic alterations. The abnormal expressions of oncogenes are regarded to be responsible for the production of malignant phenotype, subsequent invasion and metastasis. From 63 surgically resectable colorectal adenocarcinoma patients, expression of oncogenes in colorectal cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. To evaluate the possibility of oncogenes as a prognostic factor, we studied the relationship between the expression of oncogenes and the clinicopathologic findings which are well known prognostic factors. Rates of expression in colorectal cancer tissue were 27% for c-myc, 74.6% for c-Ha-ras and 77.8% for c-erbB-2 oncogenes. The positive rate of c-erbB-2 oncogene was higher in the well differentiated group than in the poorly differentiated group. The rates of expression of c-myc and c-Ha-ras oncogenes were significantly correlated each other. Expression of these oncogenes in colorectal cancer were not correlated with the pathologic stage, location of cancer, DNA ploidy pattern and histologic differentiation except between c-erbB-2 and histologic differentiation. In conclusion, there seems to be a possibility that c-erbB-2 could be used as a prognostic factor of colorectal cancer. However, further and more intensive study seems to be required.
Adenocarcinoma
;
Antibodies, Monoclonal
;
Carcinogenesis
;
Colorectal Neoplasms*
;
DNA
;
Humans
;
Neoplasm Metastasis
;
Oncogenes*
;
Phenotype
;
Ploidies
3.Does 'Hot Bath' have effect on experimental diabetic neuropathy?.
Won Ihl RHEE ; Seung Han YANG ; Young Shin PARK ; Byung Soon SHIN ; Keun Young PARK
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(3):321-329
No abstract available.
Diabetic Neuropathies*
4.The Prognostic Significance of Blood and Lymphatic Vessels Invasion of Upper Urinary Tract Transitional Cell Carcinoma.
Tong Keun SHIN ; Hae Young PARK ; Young Nam WOO
Korean Journal of Urology 1997;38(6):615-620
The prognostic significance of vascular (blood and lymphatic vessels) invasion was evaluated in a retrospective review of 27 patients with upper urinary tract transitional cell carcinoma from January 1985 to December 1993, who underwent a nephroureterectomy with bladder cuff resection. Vascular invasion was found in 10 patients (37%). The incidence of vascular invasion was well correlated with tumor grade and stage. The incidence of postoperative metastases was significantly higher in the patients with (70%) than without (17.6%) vascular invasion (p<0.05). The survival rate of the patients with vascular invasion was significantly lower than in those without vascular invasion (p<0.01). In multivariate Cox`s regressional analysis the prognostic value of vascular invasion was independent of tumor grade and stage. These results indicate that vascular invasion should predict a more unfavorable outcome in patients with upper urinary tract transitional cell carcinoma as an independent morphological indicator.
Carcinoma, Transitional Cell*
;
Humans
;
Incidence
;
Lymphatic Vessels*
;
Neoplasm Metastasis
;
Prognosis
;
Retrospective Studies
;
Survival Rate
;
Urinary Bladder
;
Urinary Tract*
5.Laboratory and Clinical Study of Ceftizoxime Sodium (Epocelin(R)) in Infections of the Pediatric Age Group.
Keun Soo LEE ; Hahng LEE ; Jeh Hoon SHIN ; Kook Young MENG ; Dae Keun KIM ; Choon Won KIM
Journal of the Korean Pediatric Society 1984;27(7):685-701
No abstract available.
Ceftizoxime*
;
Humans
7.Estimation of Joint Risks for Developing Uterine Cervix Cancer in Korea.
Hachung YOON ; Aesun SHIN ; Sue Kyung PARK ; Myung Jin JANG ; Keun Young YOO
Korean Journal of Preventive Medicine 2002;35(3):263-268
OBJECTIVE: This study was aiming at estimating the joint effects of various risk factors associated with uterine cervix cancer in Korea. METHODS: Data obtained from a case-control study were analyzed with a multiplicative model. RESULTS: After adjustment for age and husband's educational attainments, the family history of cervical cancer (OR=2.1, 95% CI=1.2-3.9), unstable marital status due to separation, by death or divorce, etc. (OR=2.8, 95% CI=1.7-4.6), and a large number of deliveries (> or = 3 vs. nulliparous OR=6.5, 95% CI=1.4-29.9) increased the risk of uterine cervix cancer. Conversely, first sexual intercourse at an older age (> or = 25 years vs. <19 years OR=0.4, 95% CI=0.2-0.6) and husband's circumcision (OR=0.7, 95% CI=0.5-1.0) decreased the risk. In the multiplicative model, the highest joint risk (OR=39.2, 95% CI 5.9-258.9) was observed in women with a family history of uterine cervical cancer, an unstable marital status, where the ex-husband was not circumcised, with 3 or more delivery experiences, and having her first sexual intercourse when younger than 19 years of age. However, women without a family history of uterine cervix cancer, married to a circumcised husband, having had her first sexual intercourse at 25 years or older, and nulliparous, showed the lowest joint effect (OR=0.3, 95% CI=0.1-0.5). CONCLUSION: As carcinogenesis is a complex action involving various factors, we consider a joint effects approach to be appropriate in an epidemiological study on risk factors for uterine cervix neoplasms.cervix neoplasm.
Carcinogenesis
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Case-Control Studies
;
Cervix Uteri*
;
Circumcision, Male
;
Coitus
;
Divorce
;
Epidemiologic Studies
;
Female
;
Humans
;
Joints*
;
Korea*
;
Male
;
Marital Status
;
Models, Statistical
;
Risk Factors
;
Spouses
;
Uterine Cervical Neoplasms
8.Clinical study on trophoblastic disease.
Sun Woo KIM ; Hee Song CHUN ; Hyung Sun KIM ; Young Lee KIM ; Shin Keun PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1058-1067
No abstract available.
Trophoblasts*
9.Ethnic identity of Koreans in the Jilin province of China.
Seung Chul SHIN ; Dong Keun LEE ; Man Kwon KIM ; Ho Young LEE
Journal of Korean Neuropsychiatric Association 1992;31(2):384-414
No abstract available.
China*
10.Clinical Studies of Salmonellosis in Childhood.
Hong Shin JEON ; Young Jin HONG ; Myung Ik LEE ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1994;37(2):199-204
During The last 11 years from Jan. 1980 to Dec. 1990, 72 cases of salmonellosis has been admitted to the Department of Pediatrics of National Medical Center and evaluated clinical difference between typhoid fever and salmonella gastroenteritis. The results were as follows: 1) The annual incidence of salmonella gastroenteritis insalmonellosis was increased in the latter half of the eighties. 2) Both salmonellosis had its peak incidence in the summer. 3) Salmonella gastroenteritis was highest in the age of less than 5 year in contrast with the age of 6~9 year in typhoid fever. 4) The specimens isolated salmonellae were blood and stool in most cases, especially blood in typhoid fever and stool in gastroenteritis. 5) S.typhi was 16 cases, salmonella group A was 3 cases, group B was 16 cases and Group D and E were a case in each in isolated salmonellae. 6) On the antibiotic sensitivity test, S.typhi was sensitive to the most antibiotics. but the salmonella group B was relatively resisitant to Ampicillin, Carbenicillin, Tetracycline and Chloramphenicol.
Ampicillin
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Anti-Bacterial Agents
;
Carbenicillin
;
Chloramphenicol
;
Gastroenteritis
;
Incidence
;
Pediatrics
;
Salmonella
;
Salmonella Infections*
;
Tetracycline
;
Typhoid Fever