1.Postoperative Complications and Their Risk Factors of Completion Total Gastrectomy for Remnant Gastric Cancer Following an Initial Gastrectomy for Cancer
Sin Hye PARK ; Sang Soo EOM ; Bang Wool EOM ; Hong Man YOON ; Young-Woo KIM ; Keun Won RYU
Journal of Gastric Cancer 2022;22(3):210-219
Purpose:
Completion total gastrectomy (CTG) for remnant gastric cancer (RGC) is a technically demanding procedure and associated with increased morbidity. The present study aimed to evaluate postoperative complications and their risk factors following surgery for RGC after initial partial gastrectomy due to gastric cancer excluding peptic ulcer.
Materials and Methods:
We retrospectively reviewed the data of 107 patients who had previously undergone an initial gastric cancer surgery and subsequently underwent CTG for RGC between March 2002 and December 2020. The postoperative complications were graded using the Clavien-Dindo classification. Logistic regression analyses were used to determine the risk factors for complications.
Results:
Postoperative complications occurred in 34.6% (37/107) of the patients. Intraabdominal abscess was the most common complication. The significant risk factors for overall complications were multi-visceral resections, longer operation time, and high estimated blood loss in the univariate analysis. The independent risk factors were multivisceral resection (odds ratio [OR], 2.832; 95% confidence interval [CI], 1.094–7.333;P=0.032) and longer operation time (OR, 1.005; 95% CI, 1.001–1.011; P=0.036) in the multivariate analysis. Previous reconstruction type, minimally invasive approach, and current stage were not associated with the overall complications.
Conclusions
Multi-visceral resection and long operation time were significant risk factors for the occurrence of complications following CTG rather than the RGC stage or surgical approach. When multi-visceral resection is required, a more meticulous surgical procedure is warranted to improve the postoperative complications during CTG for RGC after an initial gastric cancer surgery.
2.Real-World Compliance of Surgical Treatment According to the Korean Gastric Cancer Guideline 2018: Evaluation From the Nationwide Survey Data 2019 in Korea
Sang Soo EOM ; Sin Hye PARK ; Bang Wool EOM ; Hong Man YOON ; Young-Woo KIM ; Keun Won RYU
Journal of Gastric Cancer 2023;23(4):535-548
Purpose:
This study evaluated real-world compliance with surgical treatment according to Korea's gastric cancer treatment guidelines.
Materials and Methods:
The 2018 Korean Gastric Cancer Treatment Guidelines were evaluated using the 2019 national survey data for surgically treated gastric cancer based on postoperative pathological results in Korea. In addition, the changes in surgical treatments in 2019 were compared with those in the 2014 national survey data implemented before the publication of the guidelines in 2018. The compliance rate was evaluated according to the algorithm recommended in the 2018 Korean guidelines.
Results:
The overall compliance rates in 2019 were 83% for gastric resection extent, 87% for lymph node dissection, 100% for surgical approach, and 83% for adjuvant chemotherapy, similar to 2014. Among patients with pathologic stages IB, II, and III disease who underwent total gastrectomy, the incidence of splenectomy was 8.08%, a practice not recommended by the guidelines. The survey findings revealed that 48.66% of the patients who underwent gastrectomy had pathological stage IV disease, which was not recommended by the 2019 guidelines. Compared to that in 2014, the rate of gastrectomy in stage IV patients was 54.53% in 2014. Compliance rates were similar across all regions of Korea, except for gastrectomy in patients with stage IV disease.
Conclusions
Real-world compliance with gastric cancer treatment guidelines was relatively high in Korea.
3.A clinical study on the significance of the C-reactive protein in diagnosing the chorioamnionitis in patients with premature rupture of membrane.
Soo Young CHUNG ; Soo Ha EOM ; Hyung Keun YOON ; Soo Jai SHIN ; Sung Do KIM ; Jai Yeoung AHN
Korean Journal of Obstetrics and Gynecology 1993;36(3):295-302
No abstract available.
C-Reactive Protein*
;
Chorioamnionitis*
;
Female
;
Humans
;
Membranes*
;
Pregnancy
;
Rupture*
4.A Case of Primary Nasopharyngeal Tuberculosis.
Jun Young CHOI ; Jae Wook EOM ; Chun Keun PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1997;40(6):932-936
Tuberculosis of the upper respiratory tract is an uncommon disease, and the nasopharynx is particulary a rare site. Tuberculosis of the nasopharynx is mainly secondary infection from pulmonary tuberculosis via contagious, hematogenous or lymphogenous routes. The nasopharynx may be a portal entry for tubercle bacilli in patients who develope cervical lymphadenitis. Involvement of the nasopharynx by tuberculosis may be underdiagnosed because it does not produce obvious symptoms or phyiscal signs. Recently authors experinced a case of nasopharyngeal tuberculosis, here we present this case with a review of literature.
Coinfection
;
Humans
;
Lymphadenitis
;
Nasopharynx
;
Respiratory System
;
Tuberculosis*
;
Tuberculosis, Pulmonary
5.Prognostic Value of Log Odds of Positive Lymph Nodes after Radical Surgery Followed by Adjuvant Treatment in High-Risk Cervical Cancer.
Jeanny KWON ; Keun Yong EOM ; In Ah KIM ; Jae Sung KIM ; Young Beom KIM ; Jae Hong NO ; Kidong KIM
Cancer Research and Treatment 2016;48(2):632-640
PURPOSE: The purpose of this study is to compare the prognostic efficacy of the number and location of positive lymph nodes (LN), LN ratio (LNR), and log odds of positive LNs (LODDs) in high-risk cervical cancer treated with radical surgery and adjuvant treatment. MATERIALS AND METHODS: Fifty high-risk patients who underwent radical hysterectomy and pelvic node dissection followed by adjuvant treatment were analyzed retrospectively. The patients had International Federation of Gynecology and Obstetrics (FIGO) stage IA2-IIB. Upper LN is defined as common iliac or higher LN, and LNR is the ratio of positive LNs to harvested LNs. LODDs is log odds between positive LNs and negative LNs. Radiotherapy was delivered to the whole pelvis with median 50.4 Gy/28 Fx± to the para-aortic regions. Platinum-based chemotherapy was used in most patients (93%). The median follow-up duration was 80 months. RESULTS: The 5-year disease-free survival (DFS) rate was 76.1%, and the overall survival (OS) rate was 86.4%. Treatment failure occurred in 11 patients, and distant failure (DF) was the dominant pattern (90.9%). In univariate analysis, significantly lower DFSwas observed in patients with perineural invasion, ≥ 2 LN metastases, LNR ≥ 10%, upper LN metastasis, and ≥ -1.05 LODDs. In multivariate analysis, ≥ -1.05 LODDs was the only significant factor for DFS (p=0.011). Of patients with LODDs ≥ -1.05, 40.9% experienced DF. LODDs was the only significant prognostic factor for OS as well (p=0.006). CONCLUSION: LODDs ≥ -1.05 was the only significant prognostic factor for both DFS and OS. In patients with LODDs ≥ -1.05, intensified chemotherapy might be required, considering the high rate of DF.
Disease-Free Survival
;
Drug Therapy
;
Follow-Up Studies
;
Gynecology
;
Humans
;
Hysterectomy
;
Lymph Nodes*
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Obstetrics
;
Pelvis
;
Prognosis
;
Radiotherapy
;
Retrospective Studies
;
Treatment Failure
;
Uterine Cervical Neoplasms*
6.Transumbilical Single-Incision Laparoscopic Wedge Resection for Gastric Submucosal Tumors: Technical Challenges Encountered in Initial Experience.
Ji Yeon PARK ; Bang Wool EOM ; Hongman YOON ; Keun Won RYU ; Young Woo KIM ; Jun Ho LEE
Journal of Gastric Cancer 2012;12(3):173-178
PURPOSE: To report the initial clinical experience with single-incision laparoscopic gastric wedge resection for submucosal tumors. MATERIALS AND METHODS: The medical records of 10 patients who underwent single-incision laparoscopic gastric wedge resection between July 2009 and March 2011 were reviewed retrospectively. The demographic data, clinicopathologic and surgical outcomes were assessed. RESULTS: The mean tumor size was 2.5 cm (range, 1.2~5.0 cm), and the tumors were mostly located on the anterior wall (4/10) or along the greater curvature (4/10), of the stomach. Nine of ten procedures were performed successfully, without the use of additional trocars, or conversion to laparotomy. One patient underwent conversion to multiport laparoscopic surgery, to get simultaneous cholecystectomy safely. The mean operating time was 66.5 minutes (range, 24~132 minutes), and the mean postoperative hospital stay was 5 days (range, 4~7 days). No serious perioperative complications were observed. Of the 10 submucosal tumors, the final pathologic report revealed 5 gastrointestinal stromal tumors, 4 schwannomas, and 1 heterotopic pancreas. CONCLUSIONS: Single-incision laparoscopic gastric wedge resection for gastric submucosal tumors is feasible and safe, when performed by experienced laparoscopic surgeons. This technique provides favorable cosmetic results, and also short hospital stay and low morbidity, in carefully selected candidates.
Cholecystectomy
;
Cosmetics
;
Gastrectomy
;
Gastrointestinal Stromal Tumors
;
Humans
;
Laparoscopy
;
Laparotomy
;
Length of Stay
;
Medical Records
;
Neurilemmoma
;
Retrospective Studies
;
Stomach
;
Stomach Neoplasms
;
Surgical Instruments
;
Surgical Procedures, Minimally Invasive
7.Patterns of failure and prognostic factors in resected extrahepatic bile duct cancer: implication for adjuvant radiotherapy.
Tae Ryool KOO ; Keun Yong EOM ; In Ah KIM ; Jai Young CHO ; Yoo Seok YOON ; Dae Wook HWANG ; Ho Seong HAN ; Jae Sung KIM
Radiation Oncology Journal 2014;32(2):63-69
PURPOSE: To find the applicability of adjuvant radiotherapy for extrahepatic bile duct cancer (EBDC), we analyzed the pattern of failure and evaluate prognostic factors of locoregional failure after curative resection without adjuvant treatment. MATERIALS AND METHODS: In 97 patients with resected EBDC, the location of tumor was classified as proximal (n = 26) and distal (n = 71), using the junction of the cystic duct and common hepatic duct as the dividing point. Locoregional failure sites were categorized as follows: the hepatoduodenal ligament and tumor bed, the celiac artery and superior mesenteric artery, and other sites. RESULTS: The median follow-up time was 29 months for surviving patients. Three-year locoregional progression-free survival, progression-free survival, and overall survival rates were 50%, 42%, and 52%, respectively. Regarding initial failures, 79% and 81% were locoregional failures in proximal and distal EBDC patients, respectively. The most common site was the hepatoduodenal ligament and tumor bed. In the multivariate analysis, perineural invasion was associated with poor locoregional progression-free survival (p = 0.023) and progression-free survival (p = 0.012); and elevated postoperative CA19-9 (> or =37 U/mL) did with poor locoregional progression-free survival (p = 0.002), progression-free survival (p < 0.001) and overall survival (p < 0.001). CONCLUSION: Both proximal and distal EBDC showed remarkable proportion of locoregional failure. Perineural invasion and elevated postoperative CA19-9 were risk factors of locoregional failure. In these patients with high risk of locoregional failure, adjuvant radiotherapy could be considered to improve locoregional control.
Bile Duct Neoplasms
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Bile Ducts, Extrahepatic*
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Celiac Artery
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Cystic Duct
;
Disease-Free Survival
;
Follow-Up Studies
;
Hepatic Duct, Common
;
Humans
;
Ligaments
;
Mesenteric Artery, Superior
;
Multivariate Analysis
;
Prognosis
;
Radiotherapy, Adjuvant*
;
Recurrence
;
Risk Factors
;
Survival Analysis
;
Survival Rate
8.A Case of Occipital Neuralgia in the Greater and Lesser Occipital Nerves Treated with Neurectomy by Using Transcranial Doppler Sonography: Technical Aspects.
Sang Jin JUNG ; Seong Keun MOON ; Tae Young KIM ; Ki Seong EOM
The Korean Journal of Pain 2011;24(1):48-52
Occipital neuralgia is usually defined as paroxysmal stabbing pain in the greater or lesser occipital nerve (GON or LON) distribution. In occipital neuralgia patients, surgical considerations are carefully taken into account if medical management is ineffective. However, identification of the occipital artery by palpation in patients with thick necks or small occipital arteries can be technically difficult. Therefore, we established a new technique using transcranial Doppler (TCD) sonography for more accurate and rapid identification. The patient was a 64-year-old man who had undergone C1-C3 screw fixation and presented with intractable stabbing pain in the bilateral GON and LON distributions. In cases in which pain management was performed using medication, physical therapy, nerve block, or radiofrequency thermocoagulation, substantial pain relief was not consistently achieved, and recurrence of pain was reported. Therefore, we performed occipital neurectomy of the bilateral GON and LON by using TCD sonography, which helped detect the greater occipital artery easily. After the operation, the patient's headache disappeared gradually, although he had discontinued all medication except antidepressants. We believe that this new technique of occipital neurectomy via a small skin incision performed using TCD sonography is easy and reliable, has a short operative time, and provides rapid pain relief.
Antidepressive Agents
;
Arteries
;
Electrocoagulation
;
Headache
;
Humans
;
Middle Aged
;
Neck
;
Nerve Block
;
Neuralgia
;
Operative Time
;
Pain Management
;
Palpation
;
Recurrence
;
Skin
;
Ultrasonography, Doppler, Transcranial
9.Comparative Analysis of Usefulness of Vertebral Venography on the Percutaneous Vertebroplasty for Osteoporotic Compression Fracture.
Ki Seong EOM ; Jong Tae PARK ; Seong Hoon PARK ; Seong Keun MOON ; Tae Young KIM
Journal of the Korean Geriatrics Society 2010;14(2):97-103
BACKGROUND: Percutaneous vertebroplasty (PV) is a minimally invasive, image-guided therapy used to relieve pain from osteoporotic vertebral compression fractures. Venography before injection of bone cement has been advocated as a means of identifying sites of potential venous leakage during the procedure. However, venography has been used only in selected situations, and its need is debatable. We aimed to analyze the usefulness of venography with percutaneous vertebroplasties for osteoporotic compression fractures and to report our recent experiences in treating such patients. METHODS: One hundred PVs performed on 93 patients were evaluated. To identify the usefulness of venography, our cases were divided into 2 groups. Group A patients had venographies before the PVs, whereas Group B patients were treated without venography. We analyzed their clinical status, pain status, and complications linked to leakage of bone cement. RESULTS: There were no significant differences in any of the collected data for the two groups. CONCLUSION: Our results indicate that PVs can be performed safely without venography beforehand. However, venography may be beneficial for less experienced physicians or trainees.
Fractures, Compression
;
Humans
;
Intraoperative Complications
;
Phlebography
;
Vertebroplasty
10.Comparative Analysis of Usefulness of Vertebral Venography on the Percutaneous Vertebroplasty for Osteoporotic Compression Fracture.
Ki Seong EOM ; Jong Tae PARK ; Seong Hoon PARK ; Seong Keun MOON ; Tae Young KIM
Journal of the Korean Geriatrics Society 2010;14(2):97-103
BACKGROUND: Percutaneous vertebroplasty (PV) is a minimally invasive, image-guided therapy used to relieve pain from osteoporotic vertebral compression fractures. Venography before injection of bone cement has been advocated as a means of identifying sites of potential venous leakage during the procedure. However, venography has been used only in selected situations, and its need is debatable. We aimed to analyze the usefulness of venography with percutaneous vertebroplasties for osteoporotic compression fractures and to report our recent experiences in treating such patients. METHODS: One hundred PVs performed on 93 patients were evaluated. To identify the usefulness of venography, our cases were divided into 2 groups. Group A patients had venographies before the PVs, whereas Group B patients were treated without venography. We analyzed their clinical status, pain status, and complications linked to leakage of bone cement. RESULTS: There were no significant differences in any of the collected data for the two groups. CONCLUSION: Our results indicate that PVs can be performed safely without venography beforehand. However, venography may be beneficial for less experienced physicians or trainees.
Fractures, Compression
;
Humans
;
Intraoperative Complications
;
Phlebography
;
Vertebroplasty