1.Analysis of 10,811 Cases with Acute Ischemic Stroke from Korean Stroke Registry: Hospital-Based Multicenter Prospective Registration Study.
Kyung Ho YU ; Hee Jun BAE ; Sun Uck KWON ; Dong Wha KANG ; Keun Sik HONG ; Yong Seok LEE ; Joung Ho RHA ; Ja Seong KOO ; Jong Sung KIM ; Jin Hyuck KIM ; Ju Hun LEE ; Soo Jin CHO ; Sung Hee HWANG ; San JUNG ; Moon Ku HAN ; Ki Hyun CHO ; Byeong Chae KIM ; Dong Jin SHIN ; Dae Il CHANG ; Jae Hyeon PARK ; Eung Gyu KIM ; Dae Soo JUNG ; Moo Young AHN ; Dae Hie LEE ; Kun Woo PARK ; Yong Jae KIM ; Kyung Yul LEE ; Ji Hoe HEO ; Seung Hyun KIM ; Kwang Ho LEE ; Chin Sang CHUNG ; Jae Kwan CHA ; Jun Hong LEE ; Keun Yong UHM ; Byung Chul LEE ; Jae Kyu ROH
Journal of the Korean Neurological Association 2006;24(6):535-543
BACKGROUND: Although several hospital-based stroke studies were published, there has not been any reliable data representing the clinical characteristics of stroke in Korea. We analyzed the clinical characteristics of patients with ischemic stroke registered in the Korean Stroke Registry (KSR), which is the largest prospective hospital-based nation-wide stroke registry in Korea. METHODS: The KSR provided standardized protocols for collecting data, which includes the data of demographics, subtypes of stroke, risk factors, and neurological outcome at discharge. The brain imaging studies, including CT or MRI, were performed in all cases. RESULTS: KSR registered 10,811 patients of acute ischemic stroke between Nov. 2002 and Jun. 2004. The large-artery atherosclerosis was the most common subtype (37.3%), followed by small vessel occlusion (30.8%). Hypertension (65.4%) was the most common risk factor, followed by smoking (34.5%) and diabetes (28.3%). Although most of the hypertensive and diabetic patients had been diagnosed before the stroke, less than 45.4% and 32.5% of them were under regular control. The steno-occlusive lesion of extracranial carotid artery was only 29.3% and the ratio of intra- to extracranial artery disease was more than 2 in KSR. Only 20.5% of patients were admitted within 3 hours after stroke onset and 2.1% were treated with intravenous thrombolysis. In-hospital case-fatality was 5.2%, which is relatively comparable to those of previous studies. CONCLUSIONS: The KSR provided informative data in understanding the clinical characteristics of ischemic stroke in Korea. Further analysis of KSR will facilitate clinical trials and development of guidelines for the management of stroke patients.
Arteries
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Atherosclerosis
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Carotid Arteries
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Cerebrovascular Disorders
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Demography
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Epidemiology
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Humans
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Hypertension
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Korea
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Magnetic Resonance Imaging
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Neuroimaging
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Prospective Studies*
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Registries
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Risk Factors
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Smoke
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Smoking
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Stroke*