1.Two cases of epithelioid hemangioma.
Young Lip PARK ; Kyu Uang WHANG ; Young Keun KIM
Korean Journal of Dermatology 1992;30(5):727-736
Epithelioid hemangiomo, is belong to a group of unusual vascular proliferation accompanying prominent eosinophilic infiltration. It is usually classificed as a subset of angiolymphoid hyperplasia with eosinophilia despite of its peculiar endothelial morphology(i.e., vacuolization and hobnail appearance etc.). Histopathologically, the lesion was characterized by exuberant. proliferation of capillaries, epithelioid-appearing erdothelial cell, endothelial cytoplasmic vacuolization, solid sheets of endothelial cells, massive eosinophilic infiltration and lymphoreticular hyperplasia. The lesions are most common in he head-neck region and are characterized by single or multiple smooth-top papules or plnqu s of varying colors. We report two cases of epithelioid hemangioma occurring on the left auricle and scalp. The chiet complaints were pruritus and they have been early bleeding even in trivial trauma. Microscopically, the lesions were consisted of a prolifration of small to medium-sized blood vessels surraunded by inflammatory infiltrates predominantly composed of lymphocytes, histiocytes and eosinophils. The vessels were lined by epithelioid-appearing endothelial cells haveing enlarged round nuclei and abundant easinophilic or clear cytoplasm. Some vessels showed luminal obliteration by proliferating epithelioid endothelial cells. Occasionally, blood vessels were lined by hobnailor scallop-shaped endothelial cells. In immunohistochemical finolings, the epithelioid endothelial cells or proliferated capillaries were immunoreactive to factor VII-related antigen and negative to lysozyme.
Angiolymphoid Hyperplasia with Eosinophilia
;
Blood Vessels
;
Capillaries
;
Cytoplasm
;
Endothelial Cells
;
Eosinophils
;
Hemangioma*
;
Hemorrhage
;
Histiocytes
;
Hyperplasia
;
Lymphocytes
;
Muramidase
;
Phenobarbital
;
Pruritus
;
Scalp
2.A case of malignant histiocytosis with various skin manifestations.
Seung Ho JUNG ; Kyu Wang WHANG ; Young Keun KIM
Korean Journal of Dermatology 1992;30(5):720-726
Malignant histiocytosis(MH) is a rapidly progressive and usally fatal disorder characterized clinically fever, generalized weakness, lymphadeno athy, hepatosplenomegaly accompanied by jaundice, and purpura. The frequency of skin manifestations has been repoterd about 15% of MH patients. Papules, plaques and niidules are commonly met. Histopathologically MH shows infiltrations of atypical histiocyte; with uarious maturity in many organs including skin. We present a case of a 32-year-old female with MH involving not only lymph node, liver, spleen and bone marrow but also skin with vaorious features ; erythematous papules, annular purpuric patches, subcutaneous nodules and hemomagic nodules. Immunohist,ochemically the majority of patients atypical histiocytes in lesional skin shows a-1 antitrysin positive, but lysozyme negative. It may suggest that these are poorly differentiated atypical histiocytes rather than well differentiated ones.
Adult
;
Bone Marrow
;
Female
;
Fever
;
Histiocytes
;
Histiocytic Sarcoma*
;
Humans
;
Jaundice
;
Liver
;
Lymph Nodes
;
Muramidase
;
Purpura
;
Skin Manifestations*
;
Skin*
;
Spleen
3.A Review of Treatments of Keloids with Intramarginal Surgical Excision and Postoperative Irradiation to Prevent Recurrences.
Na Young LEE ; Won Keun SONG ; Kyu Kwang WHANG
Annals of Dermatology 2004;16(4):145-152
No abstract available.
Keloid*
;
Recurrence*
4.Lichen Sclerosus et Atrophicus.
Young Keun KIM ; Kyu Uang WHANG ; Hong Jig KIM
Annals of Dermatology 1989;1(2):87-90
A 48-year-old male patient had white to ivory colored patches on brown colored bases over the right side of his back for 8 years without accompanying pruritus or pain. Six months prior to the onset of his skin eruption, he received acupuncture for the relief of right sided back pain for 1 month. Histopathologic examination of the white patches showed follicular plugging, epidermal atrophy, focal hydropic degeneration of basal cells, lymphedema of papillary dermis, thickened homogenization of collagen fibers; consistent with findings previously reported in lichen sclerosus et atrophicus. We report this case to document the occurence in an acupuncture site and stress the unusual clinical manifestation of a zosteriform distribution.
Acupuncture
;
Atrophy
;
Back Pain
;
Collagen
;
Dermis
;
Humans
;
Lichen Sclerosus et Atrophicus*
;
Lichens*
;
Lymphedema
;
Male
;
Middle Aged
;
Pruritus
;
Skin
5.Clinical Observation in Epidemic Encephalitis.
Hye Keun KIM ; Young Jong WOO ; Tai Ju WHANG ; Hyung Suk BYUN ; Chull SHON
Journal of the Korean Pediatric Society 1983;26(1):26-33
No abstract available.
Encephalitis, Arbovirus*
6.A Case of Opportunistic Skin Infection with Saccharomyces.
Hong Kyu LEE ; Kyu Wang WHANG ; So Young JIN ; Young Keun KIM
Annals of Dermatology 1997;9(1):41-45
Saccharomyces is an ascospore-producing yeast that is commonly employed in the brewery and bakery industries. We report a case of opportunistic skin infection with Saccharomyces in a 62-year-old female whose defense was impaired by immunosuppression. Previously reported cases have been treated with amphotericin B or ketoconazole and our patient respbnded to fluconazole.
Amphotericin B
;
Female
;
Fluconazole
;
Humans
;
Immunosuppression
;
Ketoconazole
;
Middle Aged
;
Saccharomyces*
;
Skin*
;
Yeasts
7.A Case of Angiocentric Lymphoma Mimicking Behcet's Disease.
Jung Youl LEE ; Kyu Wang WHANG ; Hyun CHUNG ; Young Keun KIM
Annals of Dermatology 1997;9(1):22-25
We report a case of angiocentric lymphoma in a 41-year-old female who complained chiefly of a genital ulcer and a bulging conjunctiva on the right eye. She had a history of a re-current oral ulcer over a 5 year period and a genital ulcer over 3 years. The above manifested clinical findings may suggest Behcet's disease. However, a biopsy from the upper vaginal wall and the inferior turbinate showed that atypical small and large lymphocytes with hyper-chromatic, elongated and convoluted nuclei had aggregated around the thickened blood vessels, which is consistent with angiocentric lymphoma. Immunophenotypically, the atypical cells were positive for pan T-cell markers not B-cells. Serologically, the patient showed a high titer of i?B virus viral capsid antigen(VCA) IgG.
Adult
;
B-Lymphocytes
;
Biopsy
;
Blood Vessels
;
Capsid
;
Conjunctiva
;
Female
;
Humans
;
Immunoglobulin G
;
Lymphocytes
;
Lymphoma*
;
Oral Ulcer
;
T-Lymphocytes
;
Turbinates
;
Ulcer
8.A Case of Eccrine Nevus.
Woo Kwon JUNG ; Jong Seuk LEE ; Mi Jung JUNG ; Kuy Wang WHANG ; Young Keun KIM
Annals of Dermatology 1995;7(3):270-272
Eccrine nevus is an unusual entity with various clinical manifestations. Histologically the eccrine apparatus appears simply increased in number and/or size, but structurally normal. We present a case of eccrine nevus on the dorsum of the left 3rd and 4th fingers in a 20 year-old female. The lesions were 3 × 2cm sized, well demarcated, smooth surfaced, brownish plaques with mild hyperhidrosis. Histological examination revealed hyperkeratosis in the stratum corneum and hyperpigmentation of basal layer, and an increased number of eccrine sweat glands and many eccrine coils in the dermis was seen.
Dermis
;
Female
;
Fingers
;
Humans
;
Hyperhidrosis
;
Hyperpigmentation
;
Nevus*
;
Sweat Glands
9.THE PHYSCIAL PORPERTIES OFY Y2O3-CONTAINING GLASS INFILTRATED ALUMINA CORE MADE BY PRESSURELESS POWDER PACKING METHOD.
Seung Woo WHANG ; Keun Woo LEE
The Journal of Korean Academy of Prosthodontics 1997;35(1):221-243
The objective of this study was to characterize the mechanical properties of Y2O3-containing glass infiltrated ceramic core material, which was made by pressureless powder packing method. A pure alumina powder with a grain size of about 4micrometer was packed without pressure is silicon mold to form a bar shaped sample, and applied PVA solution as a binder. Samples were sinterd at 1350degrees C for 1 hour. After cooling, Y2O3-containing glass (SiO2, Y2O3, B2O3, Al2O3, ect) was infiltrated to the sinterd samples at 1300degrees C for 2 hours and cooled. Six different proportions Y2O3 of were used to know the effect of the mismatch of the thermal expansion coefficient between alumina powder and glass. The samples were ground to 3x3x30 mm size and polished with 1microneter diamond paste. Flexural strength, fracture toughness, hardness and other physical properties were obtained, and the fractured surface was examined with SEM and EPMA. Ten samples of each group were tested and compared with In-Ceram(TM) core materials of same size made in dental laboratory. The results were as follows : 1. The flexural strengths of group 1 and 3 were significantly not different with that of In-Ceram, but other experimental groups were lower than In-Ceram. 2. The shrinkage rate of samples was 0.42% after first firing, and 0.45% after glass infiltration. Total shrinkage rate was 0.87%. 3. After first firing, porosity rate of experimental groups was 50%, compared with 22.25% of In-Ceram. After glass infiltration, porosity rate of experimental groups was 2%, and 1% in In-Ceram. 4. There was no statistical difference in hardness between two materials tested, but in fracture toughness, group 2 and 3 were higher than In-Ceram. 5. The thermal expansion coefficients of experimental groups were varied to 4.51~5.35x10-6/degrees C according to glass composition, also the flexural strengths of samples were varied. 6. In a view of SEM, many microparticles about 0.5microneter diameter and 4microneter diameter were observed in In-Ceram. But in experimental group, the size of most particles was about 4microneter, and a little microparticles was observed. The results obtained in this study showed that the mismatch of the thermal expansion coefficients between alumina powder and infiltrated glass affect the flexural strength of alumin/glass composite. The Y2O3-containing glass infiltrated ceramic core made by powder packing method will takes less time and cost with sufficient flexural strength similar to all ceramic crown made with slip casting technique.
Aluminum Oxide*
;
Ceramics
;
Edible Grain
;
Crowns
;
Diamond
;
Fires
;
Fungi
;
Glass*
;
Hardness
;
Laboratories, Dental
;
Porosity
;
Silicones
10.A Case of Hunter's Syndrome With Ivory-colored Papules.
Ki Soon NAM ; Jung Youl LEE ; Kyu Uang WHANG ; Young Keun KIM
Annals of Dermatology 1996;8(4):278-281
We report a case of Hunter' s syndrome with characteristic nodules on the upper back. The patient was a 7-year-old Korean boy who presented with ivory-colored papules and nodules on both sides of the scapula, pectoral regions and lateral aspects of the upper arms. These lesione are regarded as pathognomonic cutaneous markers for Hunter s syndrome. He also presented with truncal hypertrichosis, retarded growth, short neck, round face, claw like contractures of hands, multiple joint contractures, and a clear cornea. Severely elevated glycosaminoglycan levels were present in the patient s urine samples. The patient s 5-year-old brother had similar clinical features.
Animals
;
Arm
;
Child
;
Child, Preschool
;
Contracture
;
Cornea
;
Hand
;
Hoof and Claw
;
Humans
;
Hypertrichosis
;
Joints
;
Male
;
Mucopolysaccharidosis II*
;
Neck
;
Scapula
;
Siblings