No abstract available.
Fever* ; Seizures* ; Tuberculosis, Meningeal*

No abstract available.
Humans ; Infant*

Failure to thrive (FTT) is defined when the weight of a child is below 3rd percentile or when there is sudden weight loss in history. If organic cause of the weight loss is not found, it is called non-organic failure to thrive(NETT). Relatively little attention has been paid to NFTT in Korea for various reasons and the incidence is not known. 25 NFTT infants, aged 3 to 36 months, and 25 controls, matched by age and sex of the infants and age and education of the mothers, were studied through interviews, questionnaires and MMP1. None of the NFTT and control infants had signs of developmental delay on Korean DDST, but the NFTT babies had more negative attitudes toward foods and were viewed by their mothers as more 'difficult' compared to the controls. Screening of home situations were similar in both groups. There was no difference in reports of mothers' childhood, marital status, mental states or current relations with extended family members. Analysis of MMPI of mothers of NFTT babies showed lower T-scores in Hs (hypochondreiasis) and Hy (hysteria) and higher in Mf (masculinitty-feminity) scales than those of mothers of the controls. But most the scores of scores of MMPI of mothers were within normal limits. Conclusion:Multiple factors seem to play roles in the development of NFTT, the babies' attitudes toward food and temperament being the major ones. The relative improtance of any single factor varies according to each particular infant. Contrary to the findings of other Engligh reports, mothers' mental status was found to play negligible role in the development of NFTT in this study.
Child ; Education ; Failure to Thrive* ; Humans ; Incidence ; Infant* ; Korea ; Marital Status ; Mass Screening ; MMPI ; Mothers ; Surveys and Questionnaires ; Temperament ; Weight Loss ; Weights and Measures

No abstract available.
Hypoxia-Ischemia, Brain ; Language Development* ; Mass Screening*

No abstract available.
Child* ; Humans

A scale to screen children's behavior was developed to be used by pediatrician before examining the children brought to them for possible behavioral or developmental problems. The scale consisted of 2 parts. In the first part, there were 15 subjective questions about children's behavior and development which parents can answer in short sentences and in the second part, there were 36 behavioral items with answers in 1 to 7 grades and "yes" or "no", depending whether the each behavior caused any problem to parents. Concern score was the sum of answers of 15 subjective questions, intensity sore the sum of answers of 36 items and problem score the sum of the answers whether the behavior was a problem to parent or not. From July, 992 to October, 1993, the mothers who brought their children to the department of pediatrics of Ewha Woman's University Hospital with concern of children's behavior or development were asked to fill out the questionnaire before seeing the pediatrician. "Problem" children who were diagnosed to have one of behavioral or developmental disorders were 168 and control children in well baby clinical or with acute pediatric problems were 121 in numbers. The results were as follow: @WN 1) Diagnoses of "problem" children were, in order of frequency, infantile autism, mental retardation, developmental language disorder, Asperger's syndrome and attention deficit hyperactivity disorder. 2) All of concern, intensity and problem scores were significantly higher in "problem" children compared with those of control. 3) Specificities of concern of concern, intensity and problem scores were high but only concern sore had high sensitivity, specificity, positive prodictive value and negative predictive value. 4) Concern score can be used in screening "problem" children with score 7 as cut-off point. In conclusion, in this behavioral scale, concern score which reflect subjective view of parents on children's behavior and development can be used in screening of children with behavioral and developmental problems.
Asperger Syndrome ; Attention Deficit Disorder with Hyperactivity ; Autistic Disorder ; Child ; Diagnosis ; Humans ; Intellectual Disability ; Language Development Disorders ; Mass Screening* ; Mothers ; Parents ; Pediatrics ; Surveys and Questionnaires ; Sensitivity and Specificity

No abstract available.
Humans

No abstract available.
Pediatrics*

Allogeneic demineralized bone powder has been shown to support the osteogenesis in a variety of bone defect and extra-osseous sites. Previous several experiments have been carried out in animal models which have time-consuming and various problems. Therefore author designed some cytotoxicity tests by using of 5-diphenyl dimethyltetrazolium bromide(MTT) assay, neutral red(NR) assay, lactate dehydrogenase(LDH) activity test, sulforbodamine B (SRB) assay, and alkaline phosphatase(ALP) assay. And these method seemed to be a rapid, repeatable and believable reaction. To establish the osteogenesis capacity of allogeneic bone according to various bone preparation(defatting and demineralization), author studied the effect of allogeneic bone on well-established rat 3T3 fibroblasts and MC3TEl osteoblasts in culture to evaluate a cytotoxicity and examined the surface of allogeneic bone with scanning electron microscopy(SEM) for detecting the porositv. Defatting Demineralized Bone Powder(DDBP0 and Non-Defatting Demineralized Bone Powder(NDDBP) of particle size 212mum were prepared from rat calvarial bone and long bones. 1. Cell counts of rat 3T3 fibroblasts and MC3T3E1 osteoblasts were greater in DDBP enriched medium when compared with medium with NDDBP. Cell counts with DDBP were to different from controls. 2. Author found a little differences in cytotoxicity on 3T3 fibroblast and MC3T3E1 osteoblasts between DDBP and NDDBP with MTT assay, NR assay, LDH activity test, SRB assay, Generally, DDBP was represented less cytotoxicity than NDDBP. 3. ALP assay with MC3T3E1 osteoblasts in culture presented the less cytotoxicity and more crowding around the DDBP than NDDBP. With these findings, defatting procedure on making the demineralized bone powder have a merit for supporting osteogenesis. I should be suggested that cell culture with DDBP and NDDBP is a good method for studying induced osteogenesis.
Animals ; Cell Count ; Cell Culture Techniques ; Crowding ; Fibroblasts ; Lactic Acid ; Models, Animal ; Osteoblasts ; Osteogenesis* ; Particle Size ; Rats ; Transplants*

No abstract available.
Colitis, Ulcerative* ; Mesalamine* ; Ulcer*