1.Acute Motor Axonal Neuropathy Associated with Anti-GM1 Antibody: A case report.
Hye Won KIM ; Young Jin KO ; Kyong Hwa KIM ; Il Su KIM ; Keun Hyeung RYU
Journal of the Korean Academy of Rehabilitation Medicine 2000;24(6):1207-1212
Guillain-Barre syndrme (GBS) has several subtypes that are divided by clinical, electro- physiological, and pathological findings. A novel form of GBS, that is termed acute motor axonal neuropathy (AMAN), is characterized by the selective involvement of motor fibers, and is associated with anti-GM1 antibodies. A 8-year-old male patient were developed ascending, symmetrical paralysis, and areflexia, but no sensory disturbance. Elevated titers of serum IgG anti-GM1 antibodies were detected. His thoracolumbar spine magnetic resonance imaging (MRI) revealed thickening of cauda equina and enhancement of anterior nerve roots of T12-L1 spinal level after Gd-DTPA infusion. Electrophysiological diagnosis was acute motor axonal neuropathy (AMAN). We report this case with review of the literature.
Antibodies
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Axons*
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Cauda Equina
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Child
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Diagnosis
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Gadolinium DTPA
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Humans
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Immunoglobulin G
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Magnetic Resonance Imaging
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Male
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Paralysis
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Spine