1.Interfraction variation and dosimetric changes during image-guided radiation therapy in prostate cancer patients
Frederik FUCHS ; Gregor HABL ; Michal DEVEČKA ; Severin KAMPFER ; Stephanie E COMBS ; Kerstin A KESSEL
Radiation Oncology Journal 2019;37(2):127-133
PURPOSE: The aim of this study was to identify volume changes and dose variations of rectum and bladder during radiation therapy in prostate cancer (PC) patients. MATERIALS AND METHODS: We analyzed 20 patients with PC treated with helical tomotherapy. Daily image guidance was performed. We re-contoured the entire bladder and rectum including its contents as well as the organ walls on megavoltage computed tomography once a week. Dose variations were analyzed by means of Dmedian, Dmean, Dmax, V₁₀ to V₇₅, as well as the organs at risk (OAR) volume. Further, we investigated the correlation between volume changes and changes in Dmean of OAR.
Humans
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Organs at Risk
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Prostate
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Prostatic Neoplasms
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Radiotherapy, Image-Guided
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Radiotherapy, Intensity-Modulated
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Rectum
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Urinary Bladder