The Schirmer test was performed 1350 times in 110 normal individuals and 15 dry eye patients to investigate the significance of the test as a diagnostic method for dry eye. The reproducibility of the Schirmer test was 54.5% in normal individuals and 41.9% in dry eye patients. There was no difference in the reproducibility between the groups with topical anesthesia and those without it. The ratio of misdiagnosis by Schirmer test was 48.4%. These results suggest that it is impossible to differentiate dry eye patients from normal individuals by the Schirmer test.
Diagnostic Errors ; Humans ; Keratoconjunctivitis/*diagnosis ; Keratoconjunctivitis Sicca/*diagnosis ; Reproducibility of Results ; Time Factors

Sjogren's syndrome is an autoimmune disease that is characterized by keratoconjunctivitis sicca and xerostomia. Small-fiber neuropathy is rare, although neurological manifestations occur in as many as 30% of patients with Sjogren's syndrome. We report herein a patient with Sjogren's syndrome who presented with autonomic neuropathy and painful sensory neuropathy. Primary Sjogren's syndrome should be considered in the differential diagnosis of small-fiber neuropathy.
Autoimmune Diseases ; Diagnosis, Differential ; Humans ; Keratoconjunctivitis Sicca ; Neurologic Manifestations ; Sjogren's Syndrome ; Xerostomia

Sjogren's syndrome is a systemic disorder and characterized by keratoconjunctivitis sicca, xerostomia, and connective tissuedysfunction(arthritis). A 42 year-old Korean iemalehad progressive loss of visual acuity in both eyes. In addition she has dry eyes, dry mouth and arthritis of 8 years duration. Clinical findings include cornea punctate, filamentary karatitis and decreased lacrimal secretions of both eyes. A diagnosis of Sjogren's syndrome was made. The karatoconjunctivitis siccawas treated with artificial tear and soft contact lens.
Adult ; Arthritis ; Contact Lenses, Hydrophilic ; Cornea ; Diagnosis ; Humans ; Keratoconjunctivitis Sicca ; Mouth ; Sjogren's Syndrome* ; Tears ; Visual Acuity ; Xerostomia