No abstract available.
Keratoacanthoma*

No abstract available.
Keratoacanthoma* ; Pilomatrixoma*

No abstract available.
Animals ; Horns* ; Keratoacanthoma*

No abstract available.
Carcinoma, Basal Cell* ; Keratoacanthoma*

Keratoacanthoma is a benign neoplasm that develops as a protruding mass especially on the central part of face, We experienced a case of keratoacanthoma that developed on the nasal vestibule after the eradication of verruca vulgaris on the same site by surgical intervention 3 months before. We treated it with total excision and skin graft.
Keratoacanthoma* ; Skin ; Transplants ; Warts*

Keratoacanthoma is a rapidly growing tumor that has the tendency of spontaneous involution but it may persist for some times, continue to enlarge and may become invasive and destructive. Many modalities are available for the treatment of keratoacanthoma. Although excisional surgery is the treatment of choice, this can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable in such cases. We report two cases with unusually large or facial keratoacanthoma treated with intralesional methotrexate. One case showed complete resolution over 6 injections and the other after 2 injections. We suggest that intralesional injection of methotrexate is a simple, effective, safe and inexpensive method for the treatment of large keratoacanthoma.
Injections, Intralesional ; Keratoacanthoma* ; Methotrexate*

Keratoacanthoma is a not uncommon skin tumor characterized by rapid growth of a smooth dome-shaped nodule with a central plug of keratin, usually followed by spontaneous involution. Because the tumor leaves a nunsightly scar, this is one of the reasons why these lesions should be treated. Excision is desirable if the diagnosis is in doubt. But surgical removal may be difficult, alternative treatment approaches should be considered. We report two cases of keratocathoma successfully treated by intralesional injection of 5-fluorouracil.
Cicatrix ; Diagnosis ; Fluorouracil* ; Injections, Intralesional* ; Keratoacanthoma* ; Skin

Cutaneous horn is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign and malignant pathologic changes. We report here on a case of cutaneous horn that originated from keratoacanthoma in a 76-year-old woman. Grossly, a 2.5x0.7 cm sized yellow-white colored scaly fungating mass from an erythematous nodule was observed on the right temporal area. Histopathologically, it was reported as keratoacanthoma with cutaneous horn. The lesion was totally excised after the diagnosis.
Aged ; Animals ; Female ; Horns ; Humans ; Keratins ; Keratoacanthoma

A 63-year-old man had a huge verrucous protruding mass over the suprasternal area. The lesion enlarged rapidly over 3 mooths, and measured about 10×8 cm. The histologic finding of the biopsy specimen showed nests of squamous epithelium with central keratinization, infiltrating the dermis. The neoplasm was treated successfully with surgical excision.
Biopsy ; Dermis ; Epithelium ; Humans ; Keratoacanthoma* ; Middle Aged

Keratoacanthoma (KA) is a benign epidermal tumor, characterized by rapid and abundant growth, a tendency toward spontaneous regression and histopathologic similarity to squamous cell carcinoma (SCC). Because KA can be easily misdiagnosed as SCC, surgery is considered the treatment of choice. Recently, regression of KAs following application of 5% imiquimod cream (Aldara(R)) has been reported. We present 4 cases of KA treated with topical imiquimod, applied 3 to 4 times a week. Obvious improvement was observed after 4 to 6 weeks of application and the lesions were almost cleared leaving scars after 9 to 11 weeks. These results show that topical imiquimod can be an effective option for the conservative management of KA as previously reported. We also suggest that lesions treated with imiquimod cream should be considered for biopsy to judge histopathological remission after 5 to 8 weeks of application to shorten the duration of the treatment.
Aminoquinolines ; Biopsy ; Carcinoma, Squamous Cell ; Cicatrix ; Keratoacanthoma