No abstract available.
Keratins*

No abstract available.
Immunohistochemistry ; Keratins

Intraosseous epidermal inclusion cyst is a rare benign, cystic lesion. It is thought to result from traumatic implantation of epidermal elements into bone. Radiologic findings of intraosseous epidermal inclusion cysts are well-defined, lytic lesions. It is difficult to diagnose intraosseous epidermal inclusion cyst without pathologic diagnosis. We experienced a 43-year-old man with a history of trauma followed by painless expansion of his left thumb. Radiographs demonstrated a severe expansile, ill-defined lytic lesion with cortical destruction in the distal phalanx of left thumb, mimicking neoplastic bone lesion or infectious lesion. An intraosseous epidermal inclusion cyst was confirmed by pathologic diagnosis, which was lined by stratified squamous epithelium, containing keratinized cellular debris.
Adult ; Epithelium ; Humans ; Keratins ; Thumb

Granular parakeratosis is a recently recognized disorder of keratinization that is usually confined to intertriginous areas. The histopathologic features are distinctive and diagnostic. Rarely, histopathologic variants such as follicular granular parakeratosis and granular parakeratosis of eccrine ostia have been described. In this report, we describe a rare case of granular parakeratosis mostly confined to eccrine ostia.
Eccrine Glands ; Keratins ; Neck ; Parakeratosis

Disseminated superficial porokeratosis (DSP) is a keratinization disorder characterized by multiple small lesions with a slightly elevated, sharply defined ridge over the whole body. Inflammatory DSP has common clinical features, which involve a several-year history of asymptomatic DSP and the sudden appearance of intensively pruritic erythematous papules over the entire body. These lesions subside within several months, leaving a brownish atrophic lesion. We report on a 64-year-old man who displayed an atypical clinical feature of inflammatory DSP.
Humans ; Keratins ; Middle Aged ; Porokeratosis

Darier's disease is a genetic disorder of keratinization with autosomal dominant inheritance. Its appearance is usually in the form of greasy, crusted, keratotic yellow-brown papules and plaques found particularly on seborrheic areas of the body. However, there are some clinical variants showing atypical skin lesions. Here we report an unusual case of Darier's disease, which mainly showed prominent comedonal papules over the face.
Darier Disease ; Keratins ; Skin ; Wills

No abstract available.
Fetus* ; Humans* ; Infant, Newborn* ; Keratins*

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare disorder of keratinization, involving acrosyringium. Most cases were congenital, and showed linear distribution of multiple hyperkeratotic comedo-like papules and plaques located on acral extremities. Adult-onset cases were extremely rare in the English literatures and there have not been any reported cases in the Korean literatures. Moreover, there has been no report describing the dermoscopic features of PEODDN so far. So, we here report a rare case of adult-onset PEODDN with its dermoscopic finding and review of the relevant literatures.
Adult ; Dermoscopy ; Extremities ; Humans ; Keratins ; Nevus

Porokeratosis is a genodermatosis that is characterized by abnormal epidermal keratinization with the histologic finding of a cornoid lamella. Linear porokeratosis is an uncommon variant that presents a characteristic linear nevoid distribution along the Blaschko's lines and linear porokeratosis has the highest potential for malignant degeneration of all the porokeratoses. Many treatment modalities have been used, but the treatment outcomes are variable and the treatments are poorly standardized. We report here on a case of linear porokeratosis in a 48-year-old female who showed localized, linear, brownish macules with a well-demarcated hyperkeratotic border on the left lower abdomen and back.
Abdomen ; Female ; Humans ; Keratins ; Middle Aged ; Porokeratosis

Cutaneous horn is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign and malignant pathologic changes. We report here on a case of cutaneous horn that originated from keratoacanthoma in a 76-year-old woman. Grossly, a 2.5x0.7 cm sized yellow-white colored scaly fungating mass from an erythematous nodule was observed on the right temporal area. Histopathologically, it was reported as keratoacanthoma with cutaneous horn. The lesion was totally excised after the diagnosis.
Aged ; Animals ; Female ; Horns ; Humans ; Keratins ; Keratoacanthoma