1.MRI findings of castleman disease (Giant lymph node hyperplasia): case report.
Young Ju KIM ; Joong Wha PARK ; Whi Youl CHO ; Ki Joon SUNG ; Keon Chang SONG
Journal of the Korean Radiological Society 1993;29(2):231-235
Castleman disease is a relatively rare disease of differential diagnostic interest in patients with lymphadenophathy. The etiology and pathogenesis of the Castleman disease are still not elucidated and the MRI findings of disease has not yet been reported. Two patients with Castleman disease studied by MRI are presented: one case presented with a localized anterior mediastinal mass and the other case, with a neck mass. The lesions were characterized by relatively high signal intensities on both T1 and T2 weighted images in both cases, and significant degree of enhancement was seen in the cervical Castleman disease.
Giant Lymph Node Hyperplasia*
;
Humans
;
Lymph Nodes*
;
Magnetic Resonance Imaging*
;
Neck
;
Rare Diseases
2.The effects of mycobacterium tuberculosis on alveolar macrophages.
Keon Youl KIM ; Kye Young LEE ; In Kyu HYUN ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(6):526-535
No abstract available.
Macrophages, Alveolar*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
3.A study of lung cancers without demonstrable mass lesions on simple chest X-rays.
Gee Young SUH ; Ki Ho JEONG ; Chul Kyu YOO ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keon Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(1):15-23
No abstract available.
Lung Neoplasms*
;
Lung*
;
Thorax*
4.The effect of low-dose longterm erythromycin on bronchietasis.
Young Whan KIM ; Yeon Mok OH ; Man Pyo JUNG ; Chul Gyu YOO ; Sung Koo HAN ; Young Soo SHIM ; Keon Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1993;40(4):390-394
No abstract available.
Erythromycin*
5.Effect of guinea pig tracheal epithelium on the contraction of rat vascular smooth muscle.
O Jung KWON ; Chul Gyu YOO ; Sang Heon CHO ; In Won PARK ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keon Youl KIM ; Yong Chol HAN ; Seok Hyo SEOH ; Ki Whan KIM
Tuberculosis and Respiratory Diseases 1991;38(3):270-279
No abstract available.
Animals
;
Epithelium*
;
Guinea Pigs*
;
Guinea*
;
Muscle, Smooth, Vascular*
;
Rats*
6.The etiology of the diffuse infiltrative disease of the lung in Korea.
Joon Hee KIM ; Soo Jeon CHOI ; Dong Soon KIM ; Jee Hong YOU ; Hong Mo KANG ; Se Hwa YOU ; Sung Koo HAN ; Keon Youl KIM ; Choon Sik PARK ; Joon Lee JANG ; Young WON ; Byoung Whui CHOI
Tuberculosis and Respiratory Diseases 1991;38(1):1-7
7.The changes of arterial oxygen saturation during sleep in chronic obstructive pulmonary disease patients.
Ki Ho JEONG ; Hyung Seok CHOI ; In Gyu HYUN ; Dong Chull CHOI ; Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keon Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1991;38(3):255-261
No abstract available.
Humans
;
Oxygen*
;
Pulmonary Disease, Chronic Obstructive*
8.Migration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity.
Ji Hoon JEON ; Dong Keon KIM ; Youngmi SHIN ; Hee Yeon KIM ; Bomin SONG ; Eun Young LEE ; Jong Kwang KIM ; Hye Jin YOU ; Heesun CHEONG ; Dong Hoon SHIN ; Seong Tae KIM ; Jae Ho CHEONG ; Soo Youl KIM ; Hyonchol JANG
Experimental & Molecular Medicine 2016;48(12):e277-
A small proportion of cancer cells have stem-cell-like properties, are resistant to standard therapy and are associated with a poor prognosis. The metabolism of such drug-resistant cells differs from that of nearby non-resistant cells. In this study, the metabolism of drug-resistant lung adenocarcinoma cells was investigated. The expression of genes associated with oxidative phosphorylation in the mitochondrial membrane was negatively correlated with the prognosis of lung adenocarcinoma. Because the mitochondrial membrane potential (MMP) reflects the functional status of mitochondria and metastasis is the principal cause of death due to cancer, the relationship between MMP and metastasis was evaluated. Cells with a higher MMP exhibited greater migration and invasion than those with a lower MMP. Cells that survived treatment with cisplatin, a standard chemotherapeutic drug for lung adenocarcinoma, exhibited increased MMP and enhanced migration and invasion compared with parental cells. Consistent with these findings, inhibition of mitochondrial activity significantly impeded the migration and invasion of cisplatin-resistant cells. RNA-sequencing analysis indicated that the expression of mitochondrial complex genes was upregulated in cisplatin-resistant cells. These results suggested that drug-resistant cells have a greater MMP and that inhibition of mitochondrial activity could be used to prevent metastasis of drug-resistant lung adenocarcinoma cells.
Adenocarcinoma*
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Cause of Death
;
Cisplatin
;
Humans
;
Lung*
;
Membrane Potential, Mitochondrial
;
Metabolism
;
Mitochondria
;
Mitochondrial Membranes
;
Neoplasm Metastasis
;
Oxidative Phosphorylation
;
Parents
;
Prognosis
9.Epidemiologic features of the first MERS outbreak in Korea: focus on Pyeongtaek St. Mary's Hospital.
Kyung Min KIM ; Moran KI ; Sung Il CHO ; Minki SUNG ; Jin Kwan HONG ; Hae Kwan CHEONG ; Jong Hun KIM ; Sang Eun LEE ; Changhwan LEE ; Keon Joo LEE ; Yong Shik PARK ; Seung Woo KIM ; Bo Youl CHOI
Epidemiology and Health 2015;37(1):e2015041-
OBJECTIVES: This study investigated the epidemiologic features of the confirmed cases of Middle East Respiratory Syndrome (MERS) in Pyeongtaek St. Mary's Hospital, where the outbreak first began, in order to identify lessons relevant for the prevention and control of future outbreaks. METHODS: The patients' clinical symptoms and test results were collected from their medical records. The caregivers of patients were identified by phone calls. RESULTS: After patient zero (case #1) was admitted to Pyeongtaek St. Mary's Hospital (May 15-May 17), an outbreak occurred, with 36 cases between May 18 and June 4, 2015. Six patients died (fatality rate, 16.7%). Twenty-six cases occurred in the first-generation, and 10 in the second-generation. The median incubation period was five days, while the median period from symptom onset to death was 12.5 days. While the total attack rate was 3.9%, the attack rate among inpatients was 7.6%, and the inpatients on the eighth floor, where patient zero was hospitalized, had an 18.6% attack rate. In contrast, caregivers and medical staff showed attack rates of 3.3% and 1.1%, respectively. CONCLUSIONS: The attack rates were higher than those of the previous outbreaks in other countries. The outbreak spread beyond Pyeongtaek St. Mary's Hospital when four of the patients were moved to other hospitals without appropriate quarantine. The best method of preventing future outbreaks is to overcome the vulnerabilities observed in this outbreak, such as ward crowding, patient migration without appropriate data sharing, and the lack of an initial broad quarantine.
Caregivers
;
Cross Infection
;
Crowding
;
Disease Outbreaks
;
Epidemiology
;
Gyeonggi-do*
;
Humans
;
Information Dissemination
;
Inpatients
;
Korea*
;
Medical Records
;
Medical Staff
;
Middle East
;
Quarantine
10.Nationwide Trends in the Prevalence of Cigarette and E-cigarette Smoking among Korean Adults between 2014-2021: A Representative Serial Study of 1.2 Million Individuals.
Minji KIM ; Wonyoung CHO ; Jinseok LEE ; Yong Sung CHOI ; Seung Geun YEO ; Young Joo LEE ; Sang Youl RHEE ; Chanyang MIN ; Dong Keon YON
Biomedical and Environmental Sciences 2023;36(10):996-998