1.Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery
Masahiro KATAOKA ; Kuniyuki GOMI ; Ken ICHIOKA ; Takuya IGUCHI ; Tomoki SHIROTA ; Arano MAKINO ; Ko SHIMADA ; Kiyotomi MARUYAMA ; Motohiro MIHARA ; Shoji KAJIKAWA
Annals of Coloproctology 2023;39(4):315-325
Purpose:
C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).
Methods:
Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.
Results:
The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.
Conclusion
In patients with CRC, CAR of POD 7 was a significant prognostic factor.
Result Analysis
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