Objective To explore the value of wound blush in predicting patients' ulcer healing whom with critical limb ischemia after revascularization.Methods Retrospectively analyze the clinical data of 173 cases of critical limb ischemia with ischemic ulcers under thetreatment of endovascular therapy followed the concept of angiosome.According to the condition of wound blush after endovascular therapy,by compared the difference of limb salvage rate and ulcer healing time,and try to analyze the value of wound blush in predicting ulcer healing in patients.Results Included in the study with a total of 173 cases (173 limbs),group wound blush(+) 109 patients,group wound blush (-) 64 cases,the age,proportion of male patients,smoking history,diabetes,coronary heart disease,chronic renal insufficiency,pre and post operative ankle brachial index,were no statistical difference between the two groups.The ulcer healing time of group wound blush (+) was significantly shorter than that of group wound blush(-) (P ＜ 0.05).The rate of ulcer healing in group wound blush(+) was significantly higher than that in group wound blush(-) (P ＜ 0.05).In group wound blush(+),the cumulative rate of limb salvage was statisticallyhigher than group wound blush (-) (P ＜ 0.05).By logistic regression analysis,wound blush(-) (OR =4.5,P ＜ 0.05),IRc revascularization (OR =2.6,P ＜ 0.05) were independent risk factors of ulcer healing.Conclusions The resoult of wound blush(+) shows a good distal perfusion of foot.It can be used as a predictive factor for critical limb ischemia ischemic ulcer healing,and wound blush (-) was an independent risk factor for ulcer nonhealing.

Objective:To evaluate the association of oral lichen planus (OLP) with Candida albicans infection by Meta-analysis,and to provide basis for the antifungal treatment of OLP.Methods:Bibliographic searches were conducted in PubMed,EMBase,Medline,The Cochrane Library,CNKI,VIP,and Wanfang databases from inception to December 30 in 2016.The literatures were screened according to the inclusion and exclusion criteria by two reviewers independently,the methodology quality was evaluated after data abstraction,and then the RevMan 5.3 and Stata 12.0 software were used for Meta-analysis to calculate the crude odd ration (OR) and 95％ confidence intervals (95％ CI).Funnel plot and Egger's methods were used for the evaluation on the publication bias of papers.Results:Thirteen trials were included in this study.Collectively,1 073 OLP patients and 766 controls were available for analysis.The detection rate of Candida albicans in the OLP patients was significantly higher than that in healthy controls (OR:2.30,95％ CI:1.60-3.31,P＜0.01).Seven studies of these included literatures were performed on clinical typing of the OLP patients,and the risk of Candida albicans infection in the patients with erosive-atrophic OLP (E-OLP) was significantly increased (OR =10.12,95％ CI:4.05-25.28,P＜0.01).Conclusion:OLP has a clear association with Candida albicans infection,and this association is particularly significant in the E-OLP patients.