Male SHR used in the study were 11 and 24 weeks old.
Each age of male rats were divided in two groups, treatment group and control group, and each group consisted of 7 to 8 animals.
The animal of treatment groups were given a stimulating moxibustion of the Amon point analogus to that of human to SHR.
The amount of the stimulation were dosed by the moxa of 0.5mg per 1 gram body weight in two groups. The control group was free from stimulation.
More generously rise in blood pressure and the suppressed body weight gain were observed in the stimulated group of the 11 weeks after birth (T₁ group).
T₁ group showed significantly low blood pressure compared to that of the control by five days after the stimulation.
The stimulation group in 24 weeks after birth (T₂ group) didn't show the remarkable changes compared to that of the control.
The organ weight of the adrenal and the cerebrum were significantly high in T₁ group compared to that of the control. Result of the fixed quantity to catecholamine in serum in T₁ group didn't show the remarkable changes.
Discussion and Conclusion.
The stimulus by means of moxibustion was effective to the generously rise of blood pressure and to the suppressed body weight gain for the early stage in hypertension but not for the advance stage in hypertension.