No abstract available.
Animals ; Blastocyst* ; Embryonic Structures* ; Mice*

No abstract available.
Child* ; Estradiol* ; Humans ; Testosterone*

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

No abstract available.
Catalase ; Erythrocytes* ; Glutathione Peroxidase ; Humans ; Infant, Newborn* ; Superoxide Dismutase

We report a case of Wells' syndrome consisting chiefly of papular, vesicular, pustular and vegetative lesions on the trunk, lower extremities and palms in a 48-year-old female, though characteristic lesions of this syndrome are known to be cellulitis or urticaria like plaques. Only a few cases with such lesions as ours have been reported until now. Histologic finding showed spongiotic vesicles in the epidermis and diffuse dense infiltration of eosinophils with characteristic flame figures in the dermis. In addition, marked blood eosinophilia was noted. We tried oral prednisolone for 3 weeks, and the skin lesions improved almost completely.
Cellulitis ; Dermis ; Eosinophilia ; Eosinophils ; Epidermis ; Female ; Humans ; Lower Extremity ; Middle Aged ; Prednisolone ; Skin ; Urticaria

The nodular vasculitis described by Montgomery on 1945 and is characterized by relatively chronic, persistent, or recurrent nodular lesions of nontuberculous origin chiefly on the legs. In the differential diagnosis the following must also be considered; erythema induratum, eythema nodosum, Weber-Christian disease, erythema nodosum migrans, recurrent thrombophrebitis and periarteritis nodosa. The authors observed one case of nodular vasculitis caused by sulfa drug. This patient was diagnosed to papulonecrotic tuberculid at first and treated by prednisolone 20 mg, INH 300 mg and streptomycin l.0 gm BIW. By the treatment, the patient, was cured completly within 3 months but visited again because of recurrence after 6 months. Therefore, same medication was given, but did not show improvment and added sulfa drug, Lederkyne. But, unfortunately the skin lesions was aggrevated after sulfa medication. It was suggestive that the cause of aggrevation was sulfa drug and discontinued the sulfa drug. The skin lesions were completely cured after the drug was discontinued.
Diagnosis, Differential ; Erythema Induratum ; Erythema Nodosum ; Humans ; Leg ; Panniculitis, Nodular Nonsuppurative ; Polyarteritis Nodosa ; Prednisolone ; Recurrence ; Skin ; Streptomycin ; Tuberculosis, Cutaneous* ; Vasculitis*

No abstract available.
Humans ; Temporomandibular Joint Disorders* ; Temporomandibular Joint*

The aim of the investigation was to study the efficacy and safety of Famotidine (Gaster), a new, potent, histamine H-receptor antagonist. The Famotidine (40 mg p.o.h.s) was administered to 22 patients with 33 peptic ulcers for 4 weeks. Follow up checking was done at 2 week and 4 week by endoscopy and physical examination. All patients were carefully evaluated at regular intervals for adverse drugh reactions by clinical and laboratory examinations. By the end of study, 97% of the ulcers were healed by endoscopically and rapid and complete relief of epigastric pain was observed in all patients. Famotidine treatment was well tolerated and no alterations in laboratory tests were noted. Therfore, Famotidine was proved effective in the treatment of peptic ulcers (especially multiple ulcers) and was well tolerted on the short-term basis.
Endoscopy ; Famotidine* ; Follow-Up Studies ; Histamine ; Humans ; Peptic Ulcer* ; Physical Examination ; Ulcer

The clinical and histopathologic study of 26 cases with tsutsugamushi disease seen at the Department of Derrnatology, Kosin Medical Center, Pusan, Korea from October 1986 to December 1988 was performed. The results were summarized as follows : 1. Age distribution was from 12 to 73 years and male to female ratio was 1: 1.2 (1P, males 14 females). 2. The disease occurred from September to December in a year. The peak incidence was in October (61.5%). 3. Major clinical manifestations were as follows : Chill, fever and headache (100 %), maculopapular eruption (90.2%), eschar (88.5%) and myalgia (84.6%). 4. Eschars were distributed on the abdomen (34.8%), chest (30.4%), leg (7.4%) and ot.her sites. 5. Histopathologic findings of the erythernatous macules in 24 patients showed epiderrnal changes including exocytosis of rnononuclear cells (66.7%), liquefaction degeneration of basal cells (54.2%), spongiosis (33.3%) and epidermal cell necrosis (29.2%). Dermal changes revealed vascular dilatation and perivascular infiltration of rnononuclear cells (100%), extravasated RBC (50%), and edema of papillary dermis (45.8%). Epidermal changes around the eschar were liquefaction degeneration of basal cells (52.2%), spongiosis (43.5%) and exocytosis of mononuclear cells (30.4%). Dermal changes included vascular dilatation and perivascular mononuclear cell infiltration (100%), vessel wall necrosis (73.9%), ederna of papillary dermis (65.2%) and endothelial cell swelling (65.2%).
Abdomen ; Age Distribution ; Busan ; Dermis ; Dilatation ; Edema ; Endothelial Cells ; Exocytosis ; Female ; Fever ; Headache ; Humans ; Incidence ; Korea ; Leg ; Male ; Myalgia ; Necrosis ; Scrub Typhus* ; Thorax

No abstract available.
Humans ; Infant, Low Birth Weight* ; Infant, Newborn ; Pregnancy* ; Premature Birth*