No abstract available.
Clone Cells* ; Cloning, Organism* ; Thymidine*

No Abstract available.

BACKGROUND AND OBJECTIVE: By assessing unilateral utricular function at the acute unilateral vestinuloneuritis (Acute UVN), we sought to determine the ability of the subjective visual vertical (SVV) during eccentric rotation (dynamic SVV) in localizing the site of the lesion in unilateral vestibular neuritis (UVN). METHODS: The static SVV and dynamic SVV of fifteen patients diagnosed with acute UVN were enrolled within 10 days of onset (average 7 days). First, the static SVV was measured in a dark booth without rotation. The dynamic SVV was measured during rotation with an eccentric displacement of the head to 3.5 cm from the vertical rotation axis during a constant velocity of 300 degrees/s. RESULTS: In the acute stage of UVN, the static SVV showed an increase in deviation to the side of the lesion compared to those of normal subjects. Also, we found 73% of abnormal findings in Acute UVN patients by assessing static conventional SVV. The dynamic SVV had a statistically significant increase in deviation to the side of the lesion compared to those of normal subjects and 93% patients showed beyond normal range. CONCLUSIONS: The dynamic SVV would be an effective method in the diagnosis and localization of acute unilateral vestibularneuritis.
Axis, Cervical Vertebra ; Displacement (Psychology) ; Head ; Humans ; Vestibular Neuronitis

BACKGROUND AND OBJECTIVES: To introduce the endoscopic posterior lacrimal sac approach in dacryocystorhinostomy with its success rate and complications. MATERIALS AND METHODS: Posterior sac approach was performed on 10 patients with nasolacrimal duct obstruction from March, 1996 to May, 1997. To compare the accessibility to the lacrimal sac of anterior and posterior approach, bone thickness was measured in the anterior and posterior portion of the maxillary line on computed tomography of paranasal sinuses. Microvascular density (MVD) of the anterior ethmoid sinus mucosa and lateral nasal wall mucosa was measured to compare the degree of intraoperative mucosal bleeding. RESULTS: There was no intraoperative complications, and this technique led to complete relief of lacrimal obstruction in 9 patients (90%) with a follow up of 13 to 30 months. Bone thickness was significantly thinner in the posterior portion of the maxillary line (p<0.001). MVD was higher in the ethmoid sinus mucosa than in the lateral nasal wall mucosa, but it was not significant statistically (p>0.05). CONCLUSION: Posterior lacrimal sac approach has many advantages such as better assessibility to the sac, saving the operation time, and high success rate. Therefore, attempted by those who are experienced in endoscopic techniques, posterior lacrimal sac approach appears to be useful procedure in the surgical treatment of nasolacrimal duct obstruction.
Dacryocystorhinostomy* ; Ethmoid Sinus ; Follow-Up Studies ; Hemorrhage ; Humans ; Intraoperative Complications ; Mucous Membrane ; Nasolacrimal Duct ; Paranasal Sinuses

Congenital middle ear cholesteatoma is a keratinizing squamous epithelial cyst that classically presents as a white "pearl" in either the anterosuperior or posterosuperior quadrants behind an intact tympanic membrane. The presenting features of congenital cholesteatoma depend upon the initial site of the disease. The most common presentation of this disease is a conductive hearing loss or a facial palsy of gradual onset. Other presentations include incapacitating vertigo with nystagmus, a feeling of fullness in the ear, frequent otalgia, an abnormal eardrum noted at physical examination for an unrelated condition and meningitis. Recently, we experienced a case of congenital cholesteatoma that was presented as a post-auricular fistula. In considering the management of such a fistula, it would be important to recognize the possibility that the disease may present in this way.
Cholesteatoma* ; Cholesteatoma, Middle Ear ; Ear ; Earache ; Facial Paralysis ; Fistula* ; Hearing Loss, Conductive ; Meningitis ; Physical Examination ; Tympanic Membrane ; Vertigo

Pilomatricomas are rare, usually benign and solitary, asymptomatic, calcifying tumors of the hair matrix cell, which mostly appear in the first and second decade of life. However, they may occur in adulthood. The most prevalent sites of pilomatricomas in children are the head and neck but they may occur anywhere. The typical presentation is a firm, slowly enlarging, freely mobile, well-circumscribed subcutaneous nodule, measuring 0.5 to 3 cm in diameter. The tumors are generally solitary, often adherent to overlying skin. Multiple pilomatricoma is relatively rare. Spontaneous regression is never observed, complete surgical excision is a treatment of choice. We present two cases of pilomatricoma arising from the right posterior auricle and the left posterior neck, which were treated with simple excision.
Child ; Hair ; Head ; Humans ; Neck* ; Pilomatrixoma* ; Skin

BACKGROUND: The prevalence of cognitive impairment in the elderly has been increasing in recent years with the growing of the aged population. Clinical assessment of cognitive function and mood is very important because cognitive impairment and depression commonly coexist in the elderly. The elderly interacts with the other family members, so cognitive impairment of the elderly influence family function. The objectives of this study were to delineate the factors correlated with cognitive function and to explore the relationship of depression and family function with cognitive function. METHODS: This study was done during 20 day period from July to August, 1996. The subjects were home residents aged 60 years or more living in a subcounty of Kyungpook Province, Korea. The final analysis included 195 subjects(male 95, female 100). The questionnaire included sociodemographic data, MMSE-K(Korean version of Mini Mental State Examination) for evaluation of cognitive function, BDI for evaluation of depression and family APGAR score for evaluation of family function. The results were analyzed by descriptive, comparative and correlative analysis. RESULTS: Mean MMSE-K score was 25.3+/-4.3 with female subjects(23.9+/-4.8) having significantly higher cognitive impairment when compaired to male subjects(26.6+/-3.2)(P<0.001). MMSE-K score was associated with gender, age, year of education(P<0.001), BDI and APGAR score(P<0.05). Religion, smoking and alcohol use were not associated with MMSE-K score. The prevalence of dementia by MMSE-K was 9.7% in definite dementia (MMSE-K<_19) and 23.1% with questionable dementia(20<_MMSE-K<_23). In male, the prevalence was 1.1% and 20.0% respectively. In female, the prevalence was 18.0% and 26% respectively, indicating difference between male and female subjects(P<0.001). CONCLUSIONS: In the elderly, female gender, older age and lower educational level were associated with cognitive function impairment. There was a positive correlation between cognitive function and family function. The group with impaired cognitive function had more depression than the normal group.
Aged* ; Apgar Score ; Dementia ; Depression* ; Female ; Gyeongsangbuk-do ; Humans ; Korea ; Male ; Prevalence ; Smoke ; Smoking ; Surveys and Questionnaires

BACKGROUND AND OBJECTIVES: The aggravating effect of the supine body position on breathing abnormalities during sleep appears to be due to the effect of gravity on the upper airway. All patients have a higher supine RDI (respiratory disturbance index) than total RDI. The body position during sleep may be the cause of night-to-night variability in the results of the polysomnography (PSG). The aim of this study is to compare the correlation of subjective symptoms with supine RDI and total RDI. MATERIALS AND METHOD: One hundred and twenty nine patients who visited for snoring and/or apnea, excessive daytime sleepiness were included in the study. All patients underwent full night PSG and were administered 10 cm visual analogue scale (VAS) for 14 symtoms and Epworth sleepiness scale (ESS). Supine RDI, lateral RDI and total RDI were measured in PSG. Patients were divided to positional patients (PP) and non-positional patients (NPP). RESULTS: Fifty of 97 obstructive sleep apnea patients (51.5%) were divided into PP group and 47 patients (48.5%) were divided into NPP group. Several symptoms had correlation with supine RDI and total RDI. In correlated symptoms, total RDI had higher correlation coefficient than supine RDI in both PP group and NPP group. CONCLUSIONS: Our results suggest that total RDI may reflect patient's subjective symptoms.
Apnea ; Gravitation ; Humans ; Polysomnography ; Respiration ; Sleep Apnea, Obstructive ; Snoring ; Supine Position

We successfully treated a case of in-stent restenosis, which presented on 6 occasions, resulting in frequent acute inferior wall myocardial infarctions, using a drug-eluting stent. This case demonstrates that drug-eluting stents offer the promise of an effective treatment for frequent in-stent restenosis, and importantly, that the underexpansion of a drug-eluting stent heightens the risk of acute or subacute stent thrombosis.
Coronary Restenosis ; Coronary Vessels* ; Drug-Eluting Stents* ; Inferior Wall Myocardial Infarction* ; Myocardial Infarction ; Stents ; Thrombosis

Dermatomyositis (DM) is an autoimmune disorder with idiopathic myopathy and characteristic skin manifestations that one often accompanied by an internal malignancy. The association between dermatomyositis and malignancy has been reported several times, although tonsillar carcinoma is extremely rare not only in far eastern populations but also in caucasian populations. We report two cases of Korean patients with dermatomyositis associated with tonsillar carcinoma.