1.Corrosion Characteristics Between Implant Fixture And Abutment Screw.
Su Jin KEE ; Hyeog Sin KWEON ; Han Chul CHOE
The Journal of Korean Academy of Prosthodontics 2000;38(1):85-97
The purpose of this study was to compare the corrosion characteristics between implant fixture and two types of abutment screw; gold screw, titanium screw. The anodic polarization behavior, the galvanic corrosion behavior, and the crevice corrosion behavior of prepared samples were investigated using potentiostat and scanning electron microscope. The results were as follows : 1. Anodic polarization behavior of samples: The primary passivation potential of implant fixture was -420mV, implant abutment was -560mV, titanium screw was -370mV and gold screw was -230mV. All samples were shown to have a high corrosion potential and good formation of passive film. The critical passive current density of gold screw was higher than of other samples and the sample of gold screw showed a unstable passive film formation at passive region. 2. Galvanic corrosion behavior of samples: Contact current density between implant fixture and titanium screw showed 8.023x 10-5C/cm2. Contact current density between implant fixture and gold screw showed 5.142x 10-5C/cm2. 3. Crevice corrosion behavior of samples : The crevice corrosion resistance of sample using titanium screw was higher than that of sample using gold screw, and a severe corrosion morphologies were observed at the fixture-screw interface by the scanning electron microscope.
Corrosion*
;
Titanium
2.The relationship between the paralytic pattern and the onset ofparalytic poliomyelitis.
Gwang Hwy KIM ; Woong IM ; Yeon Joo LEE ; Hong Soo LEE ; Kee Han KWEON
Journal of the Korean Academy of Family Medicine 1992;13(9):769-774
No abstract available.
Poliomyelitis*
3.Expression of neutralizing proteins of pseudorabies virus using recombinant baculovirus.
Chang Hee KWEON ; Soo Hwan AN ; Jae Young SONG ; Byoung Han KIM ; Jae Jin LEE ; Young Jin KEE ; Yong Soon LEE ; Maeda SUSUMU
Journal of the Korean Society of Virology 1992;22(1):45-51
No abstract available.
Baculoviridae*
;
Herpesvirus 1, Suid*
;
Pseudorabies*
4.Diffusion-Weighted Imaging Findings in Patients with Status Epilepticus: Report of Two Cases.
Sung Il JUNG ; Bae Ju KWEON ; Keon Ha KIM ; Moon Hee HAN ; Kee Hyun CHANG
Journal of the Korean Society of Magnetic Resonance in Medicine 2003;7(1):56-60
We present MR diffusion-weighted imaging (DWI) findings of status epilepticus in two patients. DWI showed a focal or diffuse hyperintensity with decreased apparent diffusion coefficient (ADC) value, indicating cytotoxic edema in the cerebral hemispheric cortices. The hyperintensities were located in the bilateral temporoparietooccipital areas and insular cortex in one patient, and unilaterally in the temporal lobe in the other patient.
Diffusion
;
Edema
;
Humans
;
Status Epilepticus*
;
Temporal Lobe
5.A Case of Coronary Arteriovenous Fistula Confirmed by Echocardiography.
Jong Eog JANG ; Weon Seung SHIN ; Kee Sik KIM ; Seong Wook HAN ; Kyeung Mok SHIN ; Seung Ho HUR ; Yoon Nyun KIM ; Kweon Bae KIM
Korean Circulation Journal 1997;27(6):652-657
Coronary arteriovenous fistula is relatively rare disease and originates more commonly in the right than in the left cononary artery. We report one case of cononary arteriovrnous fistula which we have experienced recently in 22 years old female, who has complained of dyspnea on exertion and intermittent anterior chest pain radiating to the left shoulder for several years. It was detected by transthoracic and transesophageal echocardiography and confirmed by cardiac catheterization and coronary angiography. In this case, the fistula was originated from the right coronary artery and drained into the posterior wall of the right ventricle, the coronary artery was dilated(diameter=1.5cm) and tortuous and significant shunt was measured(Qp/Qs=2.31). The opening of the fistula draining into right ventricle was obliterated with sutures.
Arteries
;
Arteriovenous Fistula*
;
Cardiac Catheterization
;
Cardiac Catheters
;
Chest Pain
;
Coronary Angiography
;
Coronary Vessels
;
Dyspnea
;
Echocardiography*
;
Echocardiography, Transesophageal
;
Female
;
Fistula
;
Heart Ventricles
;
Humans
;
Rare Diseases
;
Shoulder
;
Sutures
;
Young Adult
6.Clinical Experiences in Radiofrequency Catheter Ablation.
Yoon Nyun KIM ; Jang Ho BAE ; Kyeung Mok SHIN ; Sung Wook HAN ; Seung Ho HUH ; Kee Sik KIM ; Kweon Bae KIM
Korean Journal of Medicine 1997;52(1):75-82
OBJECTIVES: Among the current therapeutic options for paroxysmal supraventricular tachycardias, only surgery and ablative techniques are curative. However, surgery is associated with substantial cost, morbidity, and rarely death. Recently, catheter ablation techniques have been developed to treat paroxysmal supraventricular tachycardias. These techniques are effective and low-risk curative treatment for supraventricular tachycardias. This article shall describe our clinical experiences in radiofrequency catheter ablation for supraventricular tachycardias and review the literature. METHODS: The study population consisted of 154 patients with supraventricular tachycardias from January 1993 to August 1995. Eighty one patients were men and seventy three patients were women, and their mean age was 41.29 +/- 15.41 years. Radio-frequency currents(mean) were applied through a catheter electrode positioned against the mitral or tricuspid annulus or a branch of the coronary sinus or atrioventricular node. RESULTS: Among 154 patients, the mechanisms for paroxysmal supraventricular tachycardias were found to be atrioventricular reentrant tachycardia involving a concealed accessory pathway in 51(33.1%), Wolff-Parkinson-White syndrome in 57(37%), and atrioventricular nodal reentrant tachycardia in 46 (29.9%). Successful outcomes were achieved in 46 of 46 patients(100%) with atrioventricular nodal reentrant tachycardia, 7 of 8 patients(87.5%) with double accessory pathways, 69 of 72 patients(95.8%) with left-sided accessory pathway, and 19 of 28 patients (67.9%) with right-sided accessory pathway. Total 141 of 154 patients(91.6%) with supraventricular had a successful outcome with radio-frequency current application(mean). CONCLUSIONS: Radiofrequency catheter ablation techniques are highly effective in ablating accessory pathways or modifying atrioventricular node, with low morbidity and no mortality.
Accessory Atrioventricular Bundle
;
Atrioventricular Node
;
Catheter Ablation*
;
Catheters
;
Coronary Sinus
;
Electrodes
;
Female
;
Humans
;
Male
;
Mortality
;
Tachycardia
;
Tachycardia, Atrioventricular Nodal Reentry
;
Tachycardia, Supraventricular
;
Wolff-Parkinson-White Syndrome
7.The Effect of a Left Stellate Ganglion Block on Left Ventricular Function.
Jeong Uk HAN ; Cheong Kweon CHUNG ; Tae Jung KIM ; Choon Soo LEE ; Young Deog CHA ; Je Dong OH ; Hyun Kyung LIM ; Jeong Kee SEO ; Dea Hyeok KIM ; Chul Ho LEE
Korean Journal of Anesthesiology 2000;39(6):798-803
BACKGROUND: A Stellate ganglion block (SGB) is a sympathetic nerve block method which has been used most frequently in pain clinics due to its wide range of indications. However, SGB leads to regional sympathetic denervation of the heart and to changes in the hemodynamics. The aim of this study was to compare hemodynamic effects as well as echocardiographic changes after a left SGB (LSGB). METHODS: Fourteen healthy male volunteers were studied. The LSGB was performed with 1% mepicacaine 6 ml. Arterial blood pressure, electrocardiographic and echocardiographic variables were measured before the LSGB, 15 and 30 minutes after the LSGB. RESULTS: Arterial blood pressure, ejection fraction and transmitral inflow velocity variables showed no significant changes compared to pre-LSGB values. P-P interval increased significantly 15 minutes after the LSGB, and the Q-T interval increased significantly 30 minutes after the LSGB. The diastolic pulmonary venous flow velocity decreased significantly 15 minutes after the LSGB. CONCLUSIONS: These results showed that a LSGB decreased the heart rate without detrimental changes of left ventricular relaxation in healthy male volunteers.
Arterial Pressure
;
Autonomic Nerve Block
;
Echocardiography
;
Electrocardiography
;
Heart
;
Heart Rate
;
Hemodynamics
;
Humans
;
Male
;
Pain Clinics
;
Relaxation
;
Stellate Ganglion*
;
Sympathectomy
;
Ventricular Function, Left*
;
Volunteers
8.Diagnostic Efficacy of Serum Mac-2 Binding Protein Glycosylation Isomer and Other Markers for Liver Fibrosis in Non-Alcoholic Fatty Liver Diseases
Se Young JANG ; Won Young TAK ; Soo Young PARK ; Young-Oh KWEON ; Yu Rim LEE ; Gyeonghwa KIM ; Keun HUR ; Man-Hoon HAN ; Won Kee LEE
Annals of Laboratory Medicine 2021;41(3):302-309
Background:
Mac-2 binding protein glycosylation isomer (M2BPGi) has been established as a non-invasive biomarker for liver fibrosis. We evaluated the diagnostic efficacy of M2BPGi compared with those of other liver fibrosis markers in liver fibrosis in non-alcoholic fatty liver disease (NAFLD).
Methods:
We analyzed serum M2BPGi levels in 113 NAFLD patients. A pathologist graded liver fibrosis histopathologically. The diagnostic efficacies of serum M2BPGi and other liver fibrosis markers (aspartate aminotransferase to platelet ratio index, fibrosis index based on four factors, and NAFLD fibrosis score [NFS]) were evaluated using correlation, area under the ROC curve (AUC), logistic regression, and C-statistics.
Results:
Serum M2BPGi level and other liver fibrosis markers showed a moderate correlation with fibrosis grade. The AUC values of M2BPGi were 0.761, 0.819, 0.866, and 0.900 for diagnosing fibrosis (F) > 0, F > 1, F > 2, and F > 3, respectively. Logistic regression analysis showed M2BPGi as the only independent factor associated with F > 2 and F > 3. Although C-statistics showed that NFS was the best diagnostic factor for F > 2 and F > 3, M2BPGi with NFS had an increased C-statistics value, indicating that it is a better diagnostic model.
Conclusions
The serum M2BPGi level increased with liver fibrosis severity and could be a good biomarker for diagnosing advanced fibrosis and cirrhosis in NAFLD patients. A well-controlled, prospective study with a larger sample size is needed to validate the diagnostic power of M2BPGi and other fibrosis markers in NAFLD.
9.Clinical Status in Patients Who Restrictive Pattern on Doppler Transmitral Flow Pattern.
Jang Ho BAE ; Kee Sik KIM ; Chang Yeob HAN ; Seung Wook HAN ; Dae Woo HYUN ; Yi Chul SYNN ; So Young PARK ; Sang Joon LEE ; Yoon Nyun KIM ; Kweon Bae KIM
Journal of the Korean Society of Echocardiography 1997;5(1):42-50
BACKGROUND: Restrictive pattern on Doppler transmitral flow pattern represent reduced left ventricular compliance and associated with poor prognosis in patients with systolic dysfunction due to congestive heart failure or myocaridal infarction. Although there are many clinical evaluation about clinical significance of restrictive transmitral flow pattern, investigation about what kinds of disease reveal the characteristic restrictive transmitral flow pattern and significance according to criteria of restrictive transmitral flow pattern is few. Therefore, we have analyzed patients with restrictive transmitral flow pattern in order to evaluate clinical diagnosis and clinical significance according to criteria of restrictive transmitral flow pattern. METHODS: The study population consisted of 229 patients(male 129 patients, female 102 patients, mean age 40.6 years old) who show E/A ratio p 2 on Doppler echocardiography from september 1994 to aprial 1996. We have reviewed the medical records of that patients. RESULTS: 1) In case of patients more than 2 at E/A ratio, we found that subjects not related with cardiovascular diseases were 76 persons(33.2%), valvular heart disease 75 patients(32.3%), ischemic heart disease 25 patients(10.9%), cardiomyopathy 16 patients(6.9%). Among valvular heart disease, mitral regurgitation was most frequently observed(44.5%). In these patients, patients with left ventricular systolic dysfunction were 60 patients(26.2%). 2) Patients more than 2 at E/A ratio and less than 150msec at deceleration time of E wave were 126 patients(55.0%). In these patients, we found that valvular heart disease was also most frequently observed(49 patients, 38.8%), subjects not related with cardiovascular diseases 30 persons(23.8%), cardiomyopathy 15 patients(11.9%),pericarditis 7 patients(5.6%), hypertension 3 patients(2-3%). Patients with left ventricular systolic dysfunction in this group were 39 patients(31.0%). CONCLUSION: Although restrictive transmitral flow pattern on Doppler echocardiography represents reduced compliance of left ventricle or severe heart failure in patients with symptoms of congestive heart failure, this pattern also may be seen in persons not related with cardiovascular disease. Therefore, when making dicision about clinical significance of restrictive pattern, one should consider about any factors can influece the transmitral flow pattern and correlate the clinical diagnosis with mitral flow velocity.
Cardiomyopathies
;
Cardiovascular Diseases
;
Compliance
;
Deceleration
;
Diagnosis
;
Echocardiography, Doppler
;
Female
;
Heart Failure
;
Heart Valve Diseases
;
Heart Ventricles
;
Humans
;
Hypertension
;
Infarction
;
Medical Records
;
Mitral Valve Insufficiency
;
Myocardial Ischemia
;
Prognosis
10.Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats.
Hyun Wook KIM ; Woo Jin SONG ; Qiang LI ; Sei Myoung HAN ; Kee Ok JEON ; Sang Chul PARK ; Min Ok RYU ; Hyung Kyu CHAE ; Kweon KYEONG ; Hwa Young YOUN
Journal of Veterinary Science 2016;17(4):539-548
Severe acute pancreatitis (SAP) is associated with systemic complications and high mortality rate in dogs. Mesenchymal stem cells (MSCs) have been investigated for their therapeutic potential in several inflammation models. In the present study, the effects of canine adipose tissue-derived (cAT)-MSCs in a rat model of SAP induced by retrograde injection of 3% sodium taurocholate solution into the pancreatic duct were investigated. cAT-MSCs labeled with dioctadecyl-3,3,3′-tetramethylindo-carbocyanine perchlorate (1 × 10⁷ cells/kg) were systemically administered to rats and pancreatic tissue was collected three days later for histopathological, quantitative real-time polymerase chain reaction, and immunocytochemical analyses. Greater numbers of infused cAT-MSCs were detected in the pancreas of SAP relative to sham-operated rats. cAT-MSC infusion reduced pancreatic edema, inflammatory cell infiltration, and acinar cell necrosis, and decreased pancreatic expression of the pro-inflammatory cytokines tumor necrosis factor-α, interleukin (IL)-1β, -6, -12, -17, and -23 and interferon-γ, while stimulating expression of the anti-inflammatory cytokines IL-4 and IL-10 in SAP rats. Moreover, cAT-MSCs decreased the number of clusters of differentiation 3-positive T cells and increased that of forkhead box P3-positive T cells in the injured pancreas. These results indicate that cAT-MSCs can be effective as a cell-based therapeutic strategy for treatment of SAP in dogs.
Acinar Cells
;
Animals
;
Anti-Inflammatory Agents
;
Cytokines
;
Dogs
;
Edema
;
Inflammation
;
Interleukin-10
;
Interleukin-4
;
Interleukins
;
Mesenchymal Stromal Cells*
;
Models, Animal
;
Mortality
;
Necrosis
;
Pancreas
;
Pancreatic Ducts
;
Pancreatitis*
;
Rats*
;
Real-Time Polymerase Chain Reaction
;
T-Lymphocytes*
;
T-Lymphocytes, Regulatory
;
Taurocholic Acid