No abstract available.
Giant Cell Tumors* ; Giant Cells* ; Tendons*

2 patients of forearm deformities with ulnar defect and radial head dislocation were treated with the Ilizarov apparatus at Chungnam University Hospital. One patient had a severe hypoplastic remnant-like ulnar fragment and a anterolaterally dislocated radial head due to complicated osteomyelitis of ulnar. We applied an Ilizarov apparatus to transport the radial head distally, and fixed to remaining proximal ulnar fragment. The other had a large bony defect at the ulnar shaft and a dislocated radial head due to complicated osteomyelitis of ulna. We performed internal transport of ulna to decreased the ulnar defect and to descend the dislocated radial head. The clinical-radiological features and functional results of those 2 forearm deformities were described with brief review of the articles about the Ilizarov method for correction of forearm defor- mities.
Chungcheongnam-do ; Congenital Abnormalities ; Dislocations ; Forearm ; Head ; Humans ; Ilizarov Technique ; Osteomyelitis ; Ulna

BACKGROUND: The hypereosinophilic syndrome(HES) represents a leukoproliferative process likely caused by a number of disorders, all of which are marked by sustained over-production of eosinophils. OBJECTIVES: The purposes of this study were aimed at evaluating the clinical and histopathological characteristics of HES. METHODS: The medical records and hist opathological slides of patients with HES who had skin biopsies performed in our department were reviewed. Criteria for the diagnosis of HES include (1) peripheral blood eosinophilia with eosinophil counts greater than 1,500/L for at least 6 months; (2) no evidence of parasitic, allergic, or other known causes of eosinophilia; and (3) presumptive signs and symptoms of multiple organ involvement. RESULTS: Four male and three female patients were included. HES developed in adulthood or old age (mean, 43.4 years). Because only the patients with cutaneous involvement were included, all the patients showed skin lesions. Heart, liver, stomach, nervous system, lymph nodes, and lung were involved organs in decreasing order of frequency. At the onset of HES, 40 to 80% of white blood cells were eosinophils in peripheral blood. White blood cell count and serum IgE level were elevated in all the tested patients. In six patients (85.7%), the level of serum erythrocyte sedimentation rate was elevated. Persistent hypereosinophilia (>1,500/L) was present for longer than 6 months in all patients. Stool examination and skin test for parasitic infestation all gave negative results. All the patients were not taking any medication. Histopathological examinations revealed perivascular mixed inflammatory cell infiltration; predominantly eosinophils in the stomach, liver, and nerve as well as in the skin. Interestingly, two patients who were presented with skin lesions showed the findings of eosinophilic vasculitis. In these patients, the skin lesions were consisted of Raynaud's phenomenon, digital gangrene, and several erythematous plaques. The most common cutaneous manifestations were papules and nodules on the extremities. The main treatment modality was systemic steroid. Except for one patient presented with central nervous system involvement of HES, all the patients were in a well-controlled state. In one patient with the typical clinical and hematologic features of HES, Hodgkin's disease followed. After the complete remission of Hodgkin's disease with chemotherapy, HES subsided. CONCLUSIONS: HES is a heterogenous collection of disorders marked by hypereosinophilia and organ damage. Most common cutaneous manifestations were papules and nodules on the extremities. Raynaud's phenomenon and digital gangrene can be the primary manifestation of HES in which cases cutaneous lesions showed eosinophilic vasculitis. Five patients (71%) responded well to systemic steroids. HES may be a herald of malignancy such as Hodgkin's disease. Further investigation will be mandatory ro elucidate the etiology and pathogenesis of HES.
Biopsy ; Blood Sedimentation ; Central Nervous System ; Diagnosis ; Drug Therapy ; Eosinophilia ; Eosinophils ; Extremities ; Female ; Gangrene ; Heart ; Hodgkin Disease ; Humans ; Hypereosinophilic Syndrome* ; Immunoglobulin E ; Leukocyte Count ; Leukocytes ; Liver ; Lung ; Lymph Nodes ; Male ; Medical Records ; Nervous System ; Skin ; Skin Tests ; Steroids ; Stomach ; Vasculitis

BACKGROUND: Warts are common virus-induced lesions that are troublesome to treat, especially in children. Recently, some trials have suggested that the pulsed dye laser may also be useful for the treatment of warts. OBJECTIVE: To determine the effectiveness and safety of 585nm flashlamp-pumped pulsed dye laser treatment of warts. METHODS: Fifty patients representing a total of 265 warts were recruited for the study. Patients were treated using the flashlamp-pumped pulsed dye laser with a pulse duration of 450 sec, a spot size of 5mm, and energy fluence ranging between 7 to 9 J/cm2. Patients in whom no visible evidence of warts remained before 5 treatment sessions were classified as 'cured'. RESULTS: The cure rates were 89% for hand warts, 21% for plantar warts, 58% for periungual or subungual warts, 98% for limb warts and 100% for facial warts. Significant difference in the clearance rate of warts was found according to the maximum diameter of warts (≤0.3cm, >0.3cm) (<0.05). CONCLUSION: The 585nm flashlamp-pumped pulsed dye laser had potential effectiveness for the treatment of small warts on the hands, face, and limbs, but it is less effective for plan-tar warts, or larger warts.
Child ; Extremities ; Hand ; Humans ; Lasers, Dye* ; Warts*

Laugier-Hunziker syndrone is a rare, pigmentary disorder of the lips, oral mucosa, and nails. The absence of intestinal polyposis differentiated it from Peutz-Jeghers syndrome. We describe a 16-year-old boy with multiple, brownish, lenticular macules on the lips, oral mucosa, perianal area and anal mucosa, and on the digits of his fingers and toes, in wham intestinal polyposis was not detectable.
Adolescent ; Fingers ; Humans ; Intestinal Polyposis ; Lip ; Male ; Mouth Mucosa ; Mucous Membrane ; Peutz-Jeghers Syndrome ; Toes

No abstract available.
Trichotillomania*

Intravascular fasciitis (IVF), a rare distinct variant of nodular fasciitis, possesses the same clinical and histologcal features of nodular fasciitis, but in addition, involves predominantly small to medium- sized veins and/or arteries intraluminally, intramurally and extramurally. Only 3 cases of intraoral IVF have been reported in the English literature. Herein we report a case of IVF developing on the inner lower lip and it was successfully treated with simple excision.
Arteries ; Fasciitis* ; Lip ; Veins

Recent immunological investigations have demonstrated that the patients with psoriasis have various humoral and cellular immune abnormalities, such as increased serum IgG, IgE and secretory IgA, anti-IgC factor in psoriatic lesions, in peripheral blood lymphocytes and in serum, rhumatoid-like factors in IgA and IgG classes of immunoglobulins, antinuclear antibodies (ANA; reacting with the basal cell nuclei of uninvolved skin., anti-stratum corneum antibody and complements in psoriatic scales, immuoglobulin and complement bearing polymorphonuclear leucocytes in the Muro microabscess. These abnormal findings are enough to suggest an autoimmune mechanism in the pathogenesis of psoriasis. Several investigators have also reported the results of T cell enumeration in the peripheral blood in psoriatic patients. However, the results are not in general agreement,. Thee present study was undertaken to clarify any abnormality in the proportion of T cells in the peripheral blood in psoriatic patients. Forty-one patients with active psoriasis registered at the Department of Dermatology, Seoul National University Hospital entered this study from May, 1979 through April, 1980. Twelve healthy medical and paramedical personel the comprised the control group. Active and total T cells were enumerated by the method of E-rosetting technique, and the results were as follows. 1, in normal controls, the active and total T celIs identified as E rosetteforming cells accounted for 61.6+7.4% and 68.1+8.9% of the total lymphocyte population, respectively. 2. In patients with psoriasis, significant decrease of active T cells (54. 2,+11.0%,p<0.005) and total T cells (62.2+11.2%, p<0.05) was observed. More profound reduction of T cells was noted in patients with wide spread psoriasis than those with limited extent.
Antibodies, Antinuclear ; Cell Nucleus ; Complement System Proteins ; Dermatology ; Humans ; Immunoglobulin A ; Immunoglobulin A, Secretory ; Immunoglobulin E ; Immunoglobulin G ; Immunoglobulins ; Lymphocytes ; Psoriasis* ; Research Personnel ; Seoul ; Skin ; T-Lymphocytes* ; Weights and Measures

To determine the factors which can increase the failure after glaucoma filtering surgery and to evaluate the affect of Mitomycin C(MMC) on filtering surgery. We evaluated 249 eyes who underwent glaucoma filtering surgery consecutively during last 2 years in Catholic University Medical College hospitals. 129 eyes had risk factors and 68 eyes of them were treated with MMC during operation. The success rate of the group with risk factors was significantly lower (P=0.001) than that of the group without risk factors. In the risk group, MMC has increased the sucess rate (P=0.07). Previous cataract surgery, neovascularization of iris (NVI) , re-trabeculectomy, young age under 40, uveitis and diabetes were significant risk factors for surgical failure. After adjustment of each factors, previous cataract surgery, NVI, retrabeculectomy and young age still increased the failure rate significantly. Among them we were able to make reduse the effect of re-trabeculectomy and youth by using MMC during surgery. The outcome of glaucoma surgery may increase the success rate in some high risk cases.
Adolescent ; Cataract ; Filtering Surgery* ; Glaucoma* ; Humans ; Iris ; Mitomycin* ; Risk Factors* ; Uveitis

No abstract available.
Humans ; Iron* ; Peritoneal Dialysis, Continuous Ambulatory*