China ; Humans ; Poisoning ; prevention & control ; Public Health ; Public Health Administration ; World Health Organization ; Wounds and Injuries ; prevention & control

With the reform and development of higher education in China,cultural quality education in universities has obtained great achievement through practice of more than ten years.In 21st century,universities' cultural quality education is faced with new situation and tasks.Based on the existing experience,the universities should enhance understanding of cultural quality education,strengthen theoretic research and improve the whole quality of teachers,which can promote the popularization and sustainable development of cultural quality education.

The Sprouty protein can inhibit cel proliferation and induce apoptosis by specific interventions in the signaling pathways of tumor cells, such as receptor tyrosine kinase signaling pathway. The Sprouty protein, which is often associated with abnormal cell proliferation and transformation, is down-regulated in many tumors, stimulating the initiation and progression of tumors. The Sprouty protein exhibits potential for developing effective treatment against cancer. This paper reviews research progress on Sprouty protein in tumor.

ObjectiveTo compare the difference effects on the proximal stomach in rapid(intake rate 100 mL/min) and slow(intake rate 15 mL/min) LNLT.Methods Forty healthy subjects received both the rapid and slow LNLTs.The caloric density of the nutrient was 1 kcal/mL. The TVDRI and MVDRI were recorded,and the corresponding TVPS and MVPS were measured by B-ultrasound.Results(1) There were positive correlation was identified between TVDRI and TVPS,and between MVDRI and MVPS in both slow and rapid LNLTs.(2) TVDRI and MVPS in slow LNLT were significantly smaller than those in rapid LNLT,but MVDRI was significantly larger in slow LNLT than that in rapid LNLT.(3) TVDRI was much closer to TVPS in slow LNLT than those in rapid LNLT.But MVDRI was much closer to MVPS in rapid LNLT than those in slow LNLT.Conclusion Both slow and rapid LNLTs could be used to evaluate the accommodation to a meal and visceral sensitivity of the proximal stomach.The visceral sensitivity is related to the accommodation function.TVDRI of slow LNLT is more sensitive in estimating the visceral sensitivity of the proximal stomach;MVDRI of rapid LNLT is more accurate in estimating the accommodation of the proximal stomach.

Oral rehabilitation restores form and function and impacts on general health.Teeth provide a discriminating sense of touch and directional specificity for occlusal perception,management of food with mastication and swallowing,and awareness of its texture and hard-ness.Peripheral feedback for control of jaw muscles includes the enamel-dentine-pulp complex and mechanoreceptors in the periodontal tis-sues.The implications of feedback from periodontal and other intra-oral mechanoreceptors as well as changes in central representation are significant for function and adaptation to oral rehabilitation.With implants,in the absence of the periodontium and periodontal mechanore-ceptor feedback,fine motor control of mastication is reduced,but patients are still able to function adequately.Further,there is no signifi-cant difference in function with full-arch fixed prostheses on teeth in comparison with implants.Predictable implant outcomes depend on bone support.Optimum restoration design appears to be significant for bone remodelling and bone strains around implants with occlusal loading. Finite element analysis data confirmed load concentrations at the coronal bone around the upper section of the implant where bone loss is com-monly observed clinically.Load concentration increased with steeper cusp inclination and broader occlusal table and decreased with central fossa loading and narrower occlusal table size.It is recommended that occlusal design should follow a narrow occlusal table,with central fossa loading in intercuspal contact and low cusp inclination to minimise lateral loading in function and parafunction.Acknowledging these features should address potential problems associated with the occlusion in implant therapy.

With high morbidity and mortality,nosocomial bacterial meningitis(NBM)is a kind of serious nosocomial infection.Post-neurosurgical patients are at a high risk of this infection andNBM in-creases hospital stay and medical expense obviously.In this article,we reviewed recent studiesonpathogen-esis,treatment,and research progress of NBM in neurosurgical patients,and presented unresolved ques-tions and research direction in the future.

T-cell lymphoma is a rare form of non-Hodgkin lymphoma with high heterogeneity. The basic and clinical research of T cell lymphoma is lagged than B cell lymphoma. Recently, with the development of pathology and molecular biology, the level of diagnose has been raised, novel therapies such as targeted therapy and immunotherapy have been developed, these will make it possible to improve the prognosis of patients.

Objective To evaluate right ventricular(RV) myocardial profile changes in hypertensive heart disease (HHD) with normal pulmonary pressure by pulsed wave tissue Doppler imaging(PW-TDI) technique,and to assess right ventricular function.Methods Group Ⅰ was normal control,20 cases,average age (54?7) years old,while group Ⅱ was primary hypertensive heart disease,20 cases,average age (58?8) years old.PW-TDI technique was used to measure the peak systolic,early diastolic,late diastolic velocities(Sm,Em,Am) of right atrio-ventricular ring,the ratio of Em/Am,right ventricular isovolume contracting time(RIVCT) and isovolume relaxation time(RIVRT).The systolic and early and late diastolic motorial amplitude(SD,DED,DAD) were measured by M-mode echocardiography.Results In groupⅡ: Em decreased [( 16.0? 2.7)cm/s vs ( 19.5? 3.4)cm/s,P

Objective To assess the effects of intraventricular conduction abnormality on left ventricular function in dilated cardiomyopathy. Methods The study composed of 3 groups,16 patients of dilated cardiomyopathy (DCM) without wide QRS complexes, 16 patients of DCM with complete left bundle branch block(CLBBB),and 16 age-matched healthy individuals,all showing sinus rhythm and being complicated with mitral regurgitation. Pre-ejection contraction time(PET), left ventricular ejection time(LVET), left ventricular filling time(LVFT), myocardial performance index(MPI), mitral regurgitation time(MRT), stroke volume(SV) were recorded with pulsed or continuous-wave Doppler. Pulse tissue Doppler imagining(TDI) was performed to measure the time dispersity of electromechanical motion of left ventricular in systole and diastole on the atrial-ventricular annulus with mapping techniques. Results Time dispersity of electromechanical motion of adjacent left ventricular segments in systole[((77.9)?(13.6))ms vs ((52.1)?(13.2))ms vs ((28.3)?(7.2))ms, P

Objective To evaluate atrial stunning and the recovery of atrial function after successful cardioversion in the patients with atrial fibrillation by utilizing tissue Doppler imaging(TDI) and M-mode echocardiography in atria-ventricular annulus motion, together with pulsed Doppler echocardiography and apexcardiogram. Methods Thirty-four patients with atrial fibrillation received ultrasound examinations in 1 hour,1 day,1 week and 1 month after successful cardioversion. The results were compared with those of 20 age-matched healthy individuals. From the echocardiography apical 4-chamber views, the atrial mechnical activities in the mitral and tricuspid annulus were recorded using two-dimensional echocardiography guided M-mode and TDI. Furthermore, pulsed Doppler transmitral and transtricuspid inflow velocity and apexcardiogram were also recorded. Atrial stunning means the lack of atrial mechanical function after atrial electrical activity was recovered with successful cardioversion. Results Left and right atrial functions after cardioversion were both inferior to those of the healthy ones,but improved with time,up to 1 week right arial function turned basically to normal and 1 month left one recovered to normal.The incidence of atrial stunning in left and right atrium accounted for (20.6)% and (14.7)% respectively at 1 hour after successful cardioversion, (11.76)% and (14.7)% at 1 day, (6.5)% and (3.2)% at 1 week. Conclusions Both left and right atrial functions are lower than the normal after cardioversion,and atrial stunning happens in both atria.Left and right atria recover to normal respectively in 1 month and 1 week.