1.Studies on Operative Treatment of Huge Rhe gmatogenous Retinal Detachment
Journal of Third Military Medical University 1983;0(04):-
Twelve patients with huge rhegmatogenous retinal detachment were treated with electrocoagulation and/or cryosurgery supplemented with extrascleral buckling, annular knotting or macular sling technique. 11 cases were cured but failure occurred to one case. After treatment, the vision was improved in various degrees in different patients.It is concluded that even though the rhegma is large and the retina is wholly detached, the cure rate can be increased if careful preoperative examination and preparation is made, appropriate operative measures selected, electrocoagulation and cryosurgery reasonably adjusted, and the rhegma securely buckled.
7.Sorting methods of breast cancer stem cells
Chongyong GUO ; Keying SONG ; Ke LI
Journal of International Oncology 2011;38(5):358-361
In recent years, the theory of cancer stem cells has provided a new perspective on the treatment of cancers including breast cancer. The accurate sorting of breast cancer stem cells is critical. The sorting procedure is consist of 4 steps: isolation of side population, serum-free suspension culture,determination of specific cell surface markers and of the activity of aldehyde dehydrogenase 1 ( ALDH1 ) enzymatic through the ALDEFLUOR assay. Some studies choose drug resistance as an additional method for sorting cancer stem cells because of the enrichment of cancer stem cells after chemotherapy . The controversy about the sorting outcome of breast cancer stem cell mainly focus on molecular markers like CD44+ CD24- and ALDH1+ . The problem needed to be settled is to identify which sorting method and markers are appropriate.
9.Studies on the immunotherapy of EAE by adoptive transfer of immunoregulatory T cells specific for the spreading determinant
Ling YIN ; Chunjie SONG ; Ke ZHU
Chinese Journal of Immunology 1985;0(03):-
Objective:To explore the therapeutic potential of preemptive targeting of the epitope spreading cascade by adoptive transfer after EAE onset of immunoregulatory T cells specific for the MBP87-99 spreading determinant.Methods:EAE was induced by PLP139-151 in SWXJ mice, all mice were weighed and examined daily for neurologic signs. On days 6 after EAE onset, mice were injected with IL-2prom→IL-10cDNA-transfected Th2/Tr1-like T cells specific for MBP87-99,PLP104-117,or BSA. Finally demyelination was quantified by analysis of digitized images of PLP immunostained spinal cord sections.Results:Mice received Th2/Tr1-like T cells specific for MBP87-99 had a significantly improved clinical outcome(P=0.02) compared with control mice, reduction in the relapse rate and delay in mean time to onset of first relapse were also observed(P
10.Early Intervention on Intelligent Development of Premature Infants
Zunyu KE ; Meng MING ; Song LIANG
Chinese Mental Health Journal 1991;0(04):-
Objective:To investigate the effect of early intervention on intelligent development of the premature infants. Method:62 premature infants were randomly assigned to the intervention group and the control group. The early intervention began from the birth of the infants to their 2 years old.Result:At the age of one and two, the mental development index (MDI) and psychomotor development index (PDI) were significantly higher in the intervention group than in the control.Conclusion:Early intervention can improve intelligent development of premature infants.