With the reform and development of higher education in China,cultural quality education in universities has obtained great achievement through practice of more than ten years.In 21st century,universities' cultural quality education is faced with new situation and tasks.Based on the existing experience,the universities should enhance understanding of cultural quality education,strengthen theoretic research and improve the whole quality of teachers,which can promote the popularization and sustainable development of cultural quality education.

This paper proposes a teaching method on opening computer laboratory for students in medical colleges to learn and practice,designs the details of the teaching method on opening computer lab and discusses the managements of opening computer lab in our practice.

ObjectiveTo investigate the effect of subtotal gastrectomy on glucose metabolism in patients with gastric disease combined with diabetes mellitus.MethodsThe clinical data of 126 cases with gastric disease combined with diabetes mellitus receiving subtotal gastrectomy were analyzed retrospectively,including subtotal gastrectomy Billroth Ⅱ type 69 patients (Billroth Ⅱ type group),subtotal gastrectomy Billroth Ⅰ type 57 patients(Billroth Ⅰ type group).The fasting blood glucose,postprandial blood glucose before surgery and 1,3,6 months after surgery and the improvement of glucose metabolism were compared.ResultsThere was no significant difference in the fasting blood glucose,postprandial blood glucose before surgery and 1,3,6 months after surgery in Billroth Ⅰ type group (P ＞0.05).The fasting blood glucose,postprandial blood glucose 3,6 months after surgery [ (10.7 ±2.9 ),(10.4 ± 2.3 ) mmol/L and (12.4 ± 2.6),(12.0 ±3.2) mmol/L] were higher than those before surgery and 1 month after surgery [(14.1 ±3.2),(13.4 ±3.8) mmol/L and(19.0 ±3.9),(18.1 ±4.3) mmol/L] in Billroth Ⅱ type group with significant differences (P ＜ 0.05 or ＜ 0.01 ).The improving rate of glucose metabolism in Billroth Ⅰ type group [ 7.02％(4/57) ] was lower than that in Billroth Ⅱ type group [ 92.75％(64/69)] with significant difference(P ＜ 0.01 ).ConclusionsSubtotal gastrectomy has obvious effect on improving glucose metabolism in patients with gastric disease combined with diabetes mellitus.The use of subtotal gastrectomy Billroth Ⅱ type is prior to subtotal gastrectomy Billroth Ⅰ type.

Total 1049 new cases of blindness were detected by visual acuity survey in a population aged 68 or above in Changning District of Shanghai from 2003 to 2008. Among all eases 21.5% were age-related macular degeneration (AMD) blindness, with a trend of ascending from 17.7% in 2003 to 29. 9% in 2008. Most of the cases were classified as grade 3 (56. 9% ) or grade 4 (41.3%) of blindness. AMD has become one of the leading causes of blindness at present and should be the key eye disease for prevention of blindness.

Recent researches have shown that resectable pancreatic cancer can benefit from post-operative adjuvant chemoradiation, regardless its surgical margins, tumor size, lymph node involvement and the level of cell differentiation. Several phase Ⅱ clinical trials indicated a good tolerance to preoperative chemoradiation. Although there is no gold standard for treating locally advanced unresectable pancreatic cancer, gemcitabine-based chemotherapy or chemoradiation therapy can increase survival rate compared with best supportive care.

Objective:To explore the effect and mechanism of continuous dynamic pressure stress, which is produced by Swan-like shape memory connector(SMC), on osteopontin and osteonectin mRNA expression during experimental fracture healing.Methods: Bilateral humeral diaphyses of 30 adult rabbits were osteotomized in the middle and then 1 humerus was randomly chosen for internal fixation with SMC and the contralateral side was fixed with 4-hole dynamic compression plate(DCP). Six animals were sacrificed at 2, 7, 14, 28 and 56 days after operation and samples from the fracture gaps were obtained. Histological observation and RT-PCR were employed to study the expression of osteopontin and osteonectin mRNA.Results: In terms of histology, the endochondral bone formation and callus remodelling took place earlier in fractures fixed with SMC than with DCP. Osteopontin and osteonectin mRNA expression levels peaked at 14 and 28 days after the fracture, respectively. There was a delay in the increase and decrease of osteopontin and osteonectin mRNA in DCP fixed cases. Conclusion: The persistent dynamic longitudinal pressure stress produced by SMC may promote the healing process of long bones.

Objective:To observe the effects of different low intensity pulsed ultrasound(LIPUS) on proliferation of fibroblast and to screen out the optimum parameters of LIPUS.Methods:LIPUS of different frequency(1?1.2?1.7MHz)and different intensity was used to stimulate the cultured human fibroblast cells for 5 min,10 min,20 min and 30min,respectively,and examination of cell proliferation by MTT after 24h.Results:①Optical absorption value of cell activity in MTT assay increased significantly in the cell culture with LIPUS of different frequency(1?1.2?1.7MHz) and four intensity of each frequency treatment for 5,10 minutes,as compared with the control group(P

Heterogeneous-nuclear ribonucleoproteins A1 (hnRNP A1) is one of the important members of hnRNPs family. The function of hnRNP A1 is closely related to RNA transcription, mRNA translation, splicing of splicing sites, splicing site selection, pre-RNA maturation and degradation, cell proliferation and transformation. Overexpression of hnRNP A1 in various types of digestive system tumors is associated with poor prognosis and may serve as an early biomarker for cancer. This article reviews the recent advances in the development of hnRNP A1 and characterizes their roles in cellular and gene expression and in the development of human tumors, highlighting that hnRNP A1 is likely to be an important indicator for tumor prognosis and a potential drug target for the treatment.

Objective: To explore influence of rehabilitation intervention on quality of life in patients with coronary heart disease (CHD). Methods: A total of 108 CHD patients were selected from department of cardiology of our hospital. They were randomly and equally divided into routine treatment group and rehabilitation intervention group (received bedside rehabilitation intervention based on routine treatment). The course of treatment was eight weeks. The medical outcomes 36 item short form health survey (SF-36) was used to assess quality of life before and after treatment of two groups. Results: There were no significant difference in scores of SF-36 at primary evaluation between two groups, P>0.05; when re-evaluation after eight-week treatment, there were no significant difference in all scores of SF-36 in routine treatment group compared with before treatment, P>0.05. Compared with primary evaluation and routine treatment group after treatment, there were significant improvements in all indexes [Physiology: bodily pain (69.89±16.84) vs. (54.62±16.77) vs. (56.63±6.74), role-physical (54.56±35.62) vs. (29.84±39.07) vs. (29.44±37.12), general health (65.74±15.82) vs. (48.49±8.79) vs. (48.28±10.29),Psychology: vitality (62.92±14.31) vs. (37.57±16.65) vs. (38.31±16.32), role-emotional (51.37±18.94) vs. (25.05±14.57) vs. (28.27±12.04), social functioning (74.02±9.35) vs. (47.49±9.87) vs. (51.35±9.29), mental health (72.18±13.26) vs. (55.69±14.05) vs. (58.43±11.36), P<0.01 all] except physical functioning in rehabilitation intervention group after treatment. Conclusion: Rehabilitation intervention can effectively improve quality of life in patients with coronary heart disease.

Objective To observe the clinical therapeutic effect of combinational therapy (Warming Needle Moxibustion &Tuina) on patients with knee joint osteoarthritis .Methods 72 cases with definite diagnosis of knee joint osteoarthritis were ran-domlydividedintotreatmentgroup(receivedWarmingNeedleMoxibustion & Tuina)orcontrolgroup(receivedTuina)with36pa-tients in each group .The pain degree and motor function of knee joint were assessed before and after 4-courses treatment .Results The overall effect rate in treatment group was 94 .45% ,while it was 83 .33% in control group ,the difference was statistically signif-icant(P<0 .05) .VAS score and Lysholm knee scoring scale indicated that significant difference was detected in both groups after treatment(P<0 .05) ,the difference between groups was significant measured by Lysholm knee scoring scale and VAS score (P<0 .05) .Conclusion Warming Needle Moxibustion & Tuina can relieve joint pain and improve motor function of patients with knee joint osteoarthritis effectively .