1.The role of sports medicine for athletes -protection of the athletes’ lifetime healthcare-
Japanese Journal of Physical Fitness and Sports Medicine 2017;66(5):323-333
Sports medicine has played a role in athlete safety, strengthening physical ability, improving sports performance, and players’ life extension. Recently, sports medicine is adding some roles to provide lifetime healthcare for athletes including children in the development stage, active players and retired players. Concussion in sport, the effects of exercising in childhood on bone and joint health, and female athlete triad are described in this review paper. Some proposals for protection of the athletes’ lifetime healthcare are also discussed.
2.A criterion for evaluation of obesity based on the relationship between percent body fat and medical examination parameters.
HIROYUKI IMAMURA ; MASA MATSUBARA ; MASAHIRO MINAYOSHI ; MASARU IMAI ; KAZUHIRO KUNIKATA ; SHIN NAKAMURA ; DAIKICHI KOBATA ; HIROYUKI MORII
Japanese Journal of Physical Fitness and Sports Medicine 1992;41(1):70-78
A study was conducted to examine the relationship between percent body fat (%fat) and medical examination parameters. The subjects were 250 women aged 17 to 68 years, who neither drank nor smoked. The results obtained were as follows:
After controlling for the effects of age and maximal oxygen intake per kilogram body weight (VO2max/wt), %fat showed a significant correlation with high-density lipoprotein cholesterol (HDL-C), total cholesterol/HDL-C ratio (TC/HDL-C), β-lipoprotein (β-L), glutamic oxaloacetic transaminase (GOT), glutamic pyruvic tansaminase (GPT), uric acid (UA), white blood cell count (WBC), red blood cell count (RBC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) . Values of %fat calculated from each regression equation when HDL-C=38mg/dl, TC/HDL-C=4.9, β-L=500 mg/dl, GOT=41mu/ml, GPT=46 mu/ml, UA=5.7mg/dl, WBC=8500/mm3, RBC=520×104/mm3, SBP=159 mmHg, and DBP=94 mmHg were 32.2%, 31.9%, 30.8%, 35.4%, 36.4%, 31.8%, 30.7%, 35.0%, 33.8% and 32.6%, respectively.
The subjects were then divided into 2 groups, above (above group) or below (below group) 30%, 31%, 32%, 33%, 34% or 35% body fat. Wherever the subjects were divided into 2 groups at these values of %fat, the above group showed a significantly higer occurrence of abnormal values for medical parameters than the below group.
The subjects were further divided into 3 groups: 154 subjects with %fat below 29.9% (N group), 47 subjects with %fat between 30% and 34.9% (MO group), and 49 subjects with %fat above 35% (O group) . The O group showed significantly higher occurrence of abnormal values for medical parameters than the MO and N groups. The O group also showed a significantly higher mean value of DBP than the MO and N groups. Furthermore, the O group showed a significantly lower mean value of HDL-C and significantly higher mean values of TC/HDL-C, UA, GOT, GPT, SBP, FBS than the N group. There was no significant difference between the N and MO groups in the occurrence of abnormal values for medical parameters. However, the MO group showed a significantly lower mean value of HDL-C and significantly higher mean values of TC/HDL-C, UA and β-L.
These results suggest that the values of medical parameters become poorer when %fat exceeds 30%, a level widely used in Japan as a criterion for evaluation of obesity.
The subjects were further divided into 3 groups: 50 subjects who were non-obese and fit (NF group) ; 104 subjects who were non-obese and unfit (NU group) ; 88 subjects who were obese and unfit (OU group) . There were significant differences in the occurrence of abnormal values for medical parameters among these groups. The NF group showed the lowest values, followed by the NU and OU groups. Thus, it seems preferable to evaluate individuals using a combination of %fat and VO2max/wt.
3.A criterion for evaluation of obesity in men based on the relationships between percent body fat and clinical parameters.
HIROYUKI IMAMURA ; MASA MATSUBARA ; MASAHIRO MINAYOSHI ; MASARU IMAI ; KAZUHIRO KUNIKATA ; SHIN NAKAMURA ; DAIKICHI KOBATA ; HIROYUKI MORII
Japanese Journal of Physical Fitness and Sports Medicine 1992;41(3):322-329
A study was conducted to derive a criterion for evaluation of obesity based on relationships between percent body fat (%fat) and clinical parameters. The subjects were 457 men aged 18 to 73 years. The results obtained were as follows:
After controlling for the effects of age, maximal oxygen intake per kilogram body weight (VO2max/wt), alcohol intake and cigarette smoking, %fat showed significant correlations with high-density lipoprotein cholesterol (HDL-C), total cholesterol/HDL-C ratio (TC/HDL-C), fasting blood sugar (FBS), glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), γ-glutamyl transpeptidase (γ-GTP), white blood cell count (WBC), red blood cell count (RBC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) . Values of %fat estimated from borderline values of these clinical parameters ranged from 17.9% to 20.4%.
When the subjects were divided into 11 groups from a below 12% fat group to an above 22% fat group, the 18%, 20%, 21% and above 22% fat groups showed significantly higher occurrence of abnormal values for clinical parameters than the below 12% fat group.
When the subjects were divided into 2 groups, i, e, above (above group) or below (below group) 18%, 19%, 20%, or 21% body fat, the above group always showed a significantly higher occurrence of abnormal values for clinical parameters than the below group.
The subjects were further divided into 3 groups: 250 subjects with %fat below 17.9% (N group), 63 subjects with %fat between 18% and 19.9% (MO group), and 144 subjects with %fat above 20% (O group) . The O group showed the highest occurrence of abnormal values for clinical parameters, followed in order by the MO and N groups. These differences were significant. The O group showed a significantly lower mean value of HDL-C and significantly higher mean values of TC, TC/HDL-C, TG, GPT, SBP, DBP and FBS than the N group. The O group also showed significantly higher mean values for WBC and RBC than the MO and N groups. The O and MO groups showed significantly higer mean values of β-L, γ-GTP and UA than the N group.
From these results and the fact that a value above 20% fat is widely used as a criterion for evaluation of obesity, men with a %fat range of 18.0% to 19.9% are defined as mildly obese, whereas those with above 20% fat are defined as obese.
The subjects were further divided into 3 gooups: %fat below (non-obese) or above (obese) 20%, and VO2max/wt above (fit) or below (unfit) values recommended by the Ministry of Public Welfare for each age group. One hundred fifty-one subjects were non-obese and fit (NF group), 142 subjects were non-obese and unfit (NU group) and 107 subjects were obese and unfit (OU group) . The NF group showed the lowest occurrence of abnormal values for clinical parameters, followed in order by the NU and OU groups. These differences were significant. Thus, it seems appropriate to evaluate obesity by using a combination of %fat and VO2max/wt.
4.Long-term Patency of Femoro-Popliteal Bypass with Artificial Grafts
Kotaro Shiraga ; Hiroki Ooge ; Kazuhiro Kouchi ; Katsuhiko Imai ; Satoshi Kono ; Tatsuhiko Komiya ; Yoshio Kanzaki
Japanese Journal of Cardiovascular Surgery 1995;24(4):248-252
Femoropopliteal bypass (FP bypass) with woven Dacron grafts was performed in 159 legs of 122 patients from November 1980 to June 1993. The operative mortality rate was 0.8%. Actuarial analysis at 10 years for overall patency of FP bypass was 75.1% (mean follow-up 45.1 months). Both univariate and multivariate analysis revealed three risk factors affecting long-term patency; poor run off, difficulty in anticoagulation therapy and high serum cholesterol. The 5-year patency rate with these factors were 55.8% (p<0.01), 61.7% (p<0.01) and 63.9% (p<0.05), relatively. Therefore we recommend early surgical treatment, and strict control of anticoagulation and adequate treatment of hyperlipidemia are of great importance.
5.Delayed Cardiac Tamponade following Open Heart Surgery.
Tatsuhiko Komiya ; Kazuhiro Kohchi ; Katsuhiko Imai ; Kohtaro Shiraga ; Satoshi Kohno ; Yoshio Kanzaki
Japanese Journal of Cardiovascular Surgery 1995;24(6):351-354
Twenty-two cases with delayed cardiac tamponade following open cardiac surgery were divided into three groups according to the color and hematocrit value of pericardial fluid. In 7 patients (group B) more than half of pericardial fluid consisted of the patient's blood (mean hematocrit 31%), in 9 patients (group D) there was less blood (mean hematocrit 8%), and in 6 patients (group E) it was serous. In group B, compared with group E, the patients had more often received postoperative anticoagulant therapy (100% vs 37%, p<0.05), more often developed excess anticoagulation (thrombo test<15%) (71% vs 17%, p<0.05), and had undergone longer cardiopulmonary bypass (260±74 vs 194±49min, p<0.05). Postoperative anticoagulant therapy seems to be a risk for delayed cardiac tamponade due to intrapericardial bleeding.
6.Late Aortic Root Redissection Following Surgical Repair for Acute Aortic Dissection Using Gelatin-Resorcin-Formalin Glue: Report of 2 Cases
Yuji Sugawara ; Katsuhiko Imai ; Kazuhiro Kochi ; Kenji Okada ; Kazumasa Orihashi ; Taijiro Sueda
Japanese Journal of Cardiovascular Surgery 2004;33(1):22-25
Gelatin-resorcin-formalin (GRF) glue has been generally applied in the surgical treatment of acute aortic dissection. Recently, midterm or late redissection and false anastomotic aneurysm following the use of this adhesive have been reported in several articles and the toxicity of its component has been suggested to be involved in this complication. We herein report 2 cases of aortic root redissection a few years after the initial surgery for type A acute aortic dissection. In another hospital, a 57-year-old man had undergone total arch replacement for acute dissection in which the proximal end was repaired using GRF glue. The aortic root was revealed to be redissected by computed tomography (CT) 2 years after the intervention and continued to enlarge since then. This aortic complication was treated by composite graft replacement. The intraoperative findings of marked degeneration in dissected root tissue were impressive. The other patient was a 71-year-old man. He had undergone prosthetic replacement of the ascending aorta associated with aortic valve resuspension using GRF glue for acute dissection. Three years later, symptoms of cardiac failure due to aortic regurgitation (AR) occurred and necessitated surgical correction. The AR was due to the redissection of the non-coronary cusp sinus. Repair of the coronary sinus and aortic valve replacement was performed. The postoperative course was uneventful in both cases. Other papers have cautioned that this tissue adhesive should not be used in aortic valve resuspension. Intensive long-term follow-up is required for aortic dissection patients surgically treated using this glue.
7.Clinical Applications and Pitfalls of Hypothermia in Patients after Fontan's Operation.
Hideaki Ohno ; Yasuharu Imai ; Shuichi Hoshino ; Kazuaki Ishihara ; Seisuke Nakata ; Kazuhiro Seo ; Hiroyasu Misumi ; Masatugu Terada ; Takamasa Takeuchi ; Toshiharu Shin'oka
Japanese Journal of Cardiovascular Surgery 1996;25(1):7-12
This study was designed to clarify the usefulness and pitfalls of hypothermic management after Fontan's operation. Twenty-five patients who underwent Fontan's operation and received hypothermic management in an acute postoperative phase from 1974 to 1991 were divided into two groups; the alive (S) group and the dead (D) group. The lowest rectal temperature during the procedure was 32°C on average. There were no significant differences in preoperative indices of pulmonary circulation and renal function. After rewarming, PaO2 and daily urinary output were increased and central venous pressure decreased significantly in the S group. In all S group patients, urinary output was increased during hypothermia irrespective of peritoneal dialysis. Anuria occurred 2 days on average after induction of hypothermia in D group. Urinary output in D group decreased significantly for 4 days compared to S group. On the other hand, it was possible to save two patients who underwent take-down of Fontan's operation within 6 hours after the onset of anuria. We conclude that hypothermic management is useful in serious cases after Fontan's operation and that daily urinary output in relation to body weight during hypothermia is most important as an index of post operative circulation.
8.Health communication issues related to latent tuberculosis infection treatment support for the foreign-born in Japan
Lisa KAWATSU ; Akiko IMAI ; Saori KASUYA ; Kazuhiro UCHIMURA ; Akihiro OHKADO
Journal of International Health 2023;38(3):69-79
Objective To identify issues in health communication regarding treatment support for foreign-born who are diagnosed as latent tuberculosis infection (LTBI) in Japan, from the perspective of public health centers (PHCs).Methods A self-administered survey was sent to 469 PHC, between June and July 2020. The survey asked closed and open-ended questions to tuberculosis (TB) program personnel on (1) their experiences of foreign-born patients who were eligible for LTBI treatment but did not start their treatment, and who started treatment but were lost to follow-up, and (2) health communication issues with foreign-born patients. Responses were summarized descriptively for close-ended questions, and analyzed qualitatively for open-ended question.Results We obtained response from 307 PHCs, regarding 315 foreign-born patients. Twenty-five patients did not initiate, and 52 were lost to follow-up after initiating LTBI treatment. Of the 77 patients who either did not start treatment or were lost to follow-up, 45 apparently could hold everyday conversation in Japanese but had difficulties understanding technical terms, and 19 could not even exchange basic conversation, with PHC staff. Barriers to LTBI treatment initiation and completement, as perceived by PHC staff, included “lack of correct knowledge about TB and LTBI”, “different attitudes to health” and “economic difficulties”. Conclusion Issues in health communication between PHC staff and foreign-born patients included not only a language barrier, but also the unconscious mind among PHC staff, which sought reasons for refusal or termination of LTBI treatment in patients. We argue that this mind is based on positivism, whereby health personnel consider themselves as the provider of “scientific knowledge” and that “lay persons” can act rationally once enlightened. However, PHC staff may need to reflect upon such position as the provider of scientific knowledge, but instead, learn from foreign-born patients about how they perceive health, TB or LTBI, to conduct better communication.
9.Epidemiology of latent tuberculosis infection in Japan-born and foreign-born children in Japan
Saori Kasuya ; Akiko Imai ; Kazuhiro Uchimura ; Akihiro Ohkado ; Lisa Kawatsu
Western Pacific Surveillance and Response 2023;14(4):22-28
Objective: This study aims to compare the epidemiology of notifications of latent tuberculosis infection (LTBI) among Japan-born and foreign-born children in Japan between 2010 and 2020, and to assess the language used during LTBI case interviews with parents or caregivers of foreign-born children with LTBI during 2019.
Methods: Our study consisted of two parts: (1) an analysis of national data from the Japan Tuberculosis Surveillance (JTBS) system on the epidemiology of LTBI among Japan-born and foreign-born children in Japan and (2) a survey of staff at public health centres that had registered at least one foreign-born child aged <=14 years with LTBI. Data were extracted from the JTBS system for all children aged <=14 years who were newly notified as having LTBI between 2010 and 2020, and analysed to determine trends, characteristics and treatment outcomes. Staff at relevant public health centres completed a self-administered survey.
Results: A total of 7160 Japan-born and 320 foreign-born children were notified as having LTBI between 2010 and 2020. Compared with Japan-born children, foreign-born children notified as having LTBI were more likely to be older, have their mother or sibling as their source of infection and have LTBI detected via a routine school health check. At case interviews, the use of language interpretation services was limited, even when both parents were non-Japanese. No interview was directly conducted with children themselves, not even with school-aged children.
Discussion: Foreign-born children and their parents may be unfamiliar with the system of testing for TB infection and the diagnosis of LTBI in Japan in school settings. Public health centres are required to provide education to patients and their families and care that takes into account cultural and linguistic differences. However, the provision of language support during case interviews may need strengthening.
10.Terminal Anguish among Delirious Patients with Advanced Cancer: A Multicenter, Prospective, Observational Study
Natsuki KAWASHIMA ; Takayuki HISANAGA ; Jun HAMANO ; Isseki MAEDA ; Kengo IMAI ; Akihiro SAKASHITA ; Yoshihisa MATSUMOTO ; Keiichi UEMURA ; Takuya ODAGIRI ; Asao OGAWA ; Kazuhiro YOSHIUCHI ; Satoru IWASE
Palliative Care Research 2019;14(3):237-243
Objective: This study aimed to reveal the prevalence and characteristics of anguish among delirious patients with advanced cancer receiving specialized palliative care services. Methods: We conducted a subanalysis of a multicenter, prospective, observational study at 14 inpatient palliative care units and 10 general wards that offered psycho-oncology consultation service in Japan. We consecutively enrolled the patients with advanced cancer who were diagnosed with delirium and prescribed antipsychotics. Palliative care specialists decided whether patients suffered from anguish or not. We assessed patients’ background and severity of delirium with the Delirium Rating Scale-Revised (DRS-R-98). Results: Of 818 enrolled patients, 99 (12.1%) suffered from anguish. We observed a significant difference in the mean age (68.9±12.6 vs. 72.1±11.2, p=0.009), prevalence of dementia (2% vs. 10.4%, p=0.005) between patients with anguish and those without anguish. Patients with anguish had lower DRS-R-98 total scores before medication than those without anguish (15.3±8.1 vs. 17.3±7.8, p=0.018), but higher severity score in lability of affect (1.2±0.8 vs 1.0±0.9, p=0.023). Conclusions: The results of this study suggested that patients with anguish tend to be younger, mostly do not have dementia, and have lower delirium severity score but higher score in lability of affect. Nevertheless, further research, investigating appropriate evaluations and medical interventions for patients with anguish is warranted.