2.The Study on the Difficulty of the Tests of Gait Disturbance.
Kazuhiko SHIMIZU ; Hideo MIYAHARA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1998;61(2):106-114
In 61 patients with hemiplegia who were under a rehabilitation program, the grade of gait disturbance of each patient was examined by 6 physical therapists. The examination consisted of observation on 46 kinds of gait or related actions; of which 14 were with a handrail, 16 with a cane and 16 with empty hands. Each rater was requested to rate the patient's performance on the basis of 4 stages: impossible, possible with human assistance, possible but not practical, and practical from the standpoint of ADL (activities of daily living). We assigned 1 to the former two cases, whereas 0 to the latter two, respectively.
The data collected in this way were analysed by making the cross-table and counting the number of possible tests in each patient and that of possible patients in each test, respectively. By using these results, we rearranged the order of both cases and tests. We found that the rank of this new arrangement of the tests roughly paralleled to that of the difficulty of the tests and could be diverted to be utilized for the scaling of the latter.
3.Risk Factors of Progression of Diabetic Retinopathy in Patients with Poorly Controlled Diabetes.
Tomio KAMETANI ; Hideo KOSHIDA ; Kiyomori HASHIZUME ; Kazuhiko SHIBATA ; Kuniyoshi SHIMIZU ; Tateyuki HORIGAMI
Journal of the Japanese Association of Rural Medicine 2000;49(4):565-572
To determine risk factors for progression of diabetic retinopathy, a study was conducted in 92 patients with diabetes whose HbA1c levels were more than 9.5% when they were admitted to our hospital.
The progression of retinopathy was observed in 50% of the patients during 12 months after admission. Their cases were diagnosed as preproliferative retinopathy. The duration of no-treatment, serum cholesterol level, blood pressure and proteinuria were significantly greater in the deterioration group of retinopathy than in the no-deterioration group. Nerve conduction velocity was significantly lower in the deterioration group of retinopathy than in the no-deterioration group. The reduction of HbA1c level during the period of 3 months after admission was significantly higher in the deterioration group than in the improved group. In the patients whose initial levels of HbA1c were less than 10%, the deterioration of retinopathy was not observed. In conclusion, these findings suggest that the duration of no-treatment, serum cholesterol level, blood pressure, proteinuria, nerve conduction velocity, retinopathy severity, the HbA1c level at admission and the reduction of HbA1c level during the 3-month period are risk factors for the progression of retinopathy.
4.A Case of Type 1 Diabetes Mellitus with Improvement of Insulin Reserve by Glibenclamide.
Tomio KAMETANI ; Kiyomori HASHIZUME ; Kazuhiko SHIBATA ; Kuniyoshi SHIMIZU ; Hideo KOSHIDA ; Tateyuki HORIGAMI
Journal of the Japanese Association of Rural Medicine 2000;49(4):626-630
A 62-year-old woman was adimitted to our hospital because of thirst and a body weight loss of 9kg. She had a history of vasospastic breast pang 5months before. The level of fasting plasma glucose was 320 mg/dl and the level of HbA1c was 13.0%. The autoantibody to glutamic acid decarboxylase was positive. The level of urine C-peptide was 28.6μg/day. She rejected insulin injections and was treated with glibenclamide. The level of urine C-peptide increased to 70.0μg/day. The disease was controlled with the levels of 6.0% of HbA1c. But her condition became uncontrollable gradually after 6 months and she was treated by insulin therapy.
Insulin secretion in type 1 diabetes mellitus was transiently improved by sulfony 1 urea. This suggests that not only the insulin secretion but also glucotoxicity plays an important role in early stage of type 1 diabetes mellitus.
5.Effectiveness of Prospective Insulin Sliding Scale for Outpatients with Diabetes Mellitus.
Tomio KAMETANI ; Hideo KOSHIDA ; Kiyomori HASHIZUME ; Kazuhiko SHIBATA ; Kuniyoshi SHIMIZU ; Kenkou HORIGAMI
Journal of the Japanese Association of Rural Medicine 2001;50(2):102-107
The self-monitoring of blood glucose is a recommendable method for control of diabetes mellitus. But few reports of the prospective insulin sliding scale for outpatients were available in Japan. To elucidate the efficacy of the prospective insulin sliding scale for outpatients with diabetes mellitus, 14 insulin-treated patients who usedwith the prospective insulin sliding scale (scale group) and 14 insulin-treated patients who did not use with the prospective insulin sliding scale (control group) were studied over a period of 6 months.
The control group showed no significant change of Hb Aic level. But the scale group showed a significant reduction in Hb Aic level at 5 months (8.37 ± 1.14% to 7.50 ±1.42%, p<0.008). The scale group had an almost two fold increase in the frequency in hypoglycemia. However, there was no severe hypoglycamia. There were weight gains in the control group and scale group, but there was no difference between control group and scale group.
These data suggest that the prospective insulin sliding scale is useful for the better control of diabetes mellitus.
6.A Review of Coronary Artery Bypass Reoperation.
Ken-o Mashiko ; Masamichi Nakano ; Kazuhiko Suzuki ; Asatoshi Mizuno ; Yoshimasa Sakamoto ; Hiroshi Okuyama ; Shougo Shimizu ; Hiromi Kurosawa
Japanese Journal of Cardiovascular Surgery 1994;23(3):152-155
We performed coronary artery bypass operation on 258 patients from July 1974 to February 1993, of whom 10 underwent a total of 11 reoperations. These 10 patients were not significantly different from the other patients with respect to gender, coronary risk factors and number of grafts used in the first operation, aside from older age and lower LVEF. The interval between the two operations was <1 year (early) or about 10 years (late) in most instances. The most common reasons for reoperation were graft failure from technical problems in early and time-related alterations in graft and progression of original disease in late cases. The outcome of reoperation was less than satisfactory, with 2 operative deaths, IABP required in 5, reoperation for bleeding needed in 3 and severe sternal wound infection of the patent vein graft postoperatively, of which atheromatous debris released from the atherosclerotic vein graft was strongly suspected to be the cause. The old vein graft should be immediately ligated at the beginning of CPB in cases with diffuse atherosclerotic vein graft in which more than several years have passed since initial operation. In reoperation, arterial graft is preferable, especially GEA graft can be used advantageously even with a left thoracotomy approach. Bypass reoperation for occlusion of LAD or Cx should be performed by a left thoracotomy approach.
7."Inflammatory" Abdominal Aortic Aneurysm Associated with Various Atherosclerotic Lesions.
Ryo Ochiai ; Susumu Ishikawa ; Kazuhiro Sakata ; Yasushi Sato ; Akio Ohtaki ; Nao Jyoshita ; Kazuhiko Shimizu ; Norio Kanazawa ; Toyoshi Sasaki ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1998;27(1):63-66
A 61-year-old man was found to have an abdominal aortic aneurysm (AAA) during follow-up for ischemic heart disease. On admission, ultrasonograms and computed tomograms revealed a thickened aortic wall surrounded by a soft tissue (so-called mantle). The obstructive right anterior brain artery and stenotic right internal carotid artery were also detected by angiography. Coronary angiography demonstrated multiple stenotic lesions of the coronary arteries. The excised AAA was replaced with an prosthetic graft. The mobilization of the adjacent viscera was kept as little as possible in order to prevent injury to them. We reported a case of “inflammatory” abdominal aneurysm associated with various atherosclerotic lesions.
8.Clinical Outcomes of Surgical Treatments for Traumatic Spinal Injuries due to Snowboarding.
Takahiro MASUDA ; Kei MIYAMOTO ; Kazuhiko WAKAHARA ; Kazu MATSUMOTO ; Akira HIOKI ; Tetsuya SHIMOKAWA ; Katsuji SHIMIZU ; Shinji OGURA ; Haruhiko AKIYAMA
Asian Spine Journal 2015;9(1):90-98
STUDY DESIGN: Retrospective study. PURPOSE: To assess treatment outcomes of snowboarding-related spinal and spinal cord injuries. OVERVIEW OF LITERATURE: Snowboarding-related spinal or spinal cord injury have a great impact on social and sporting activities. METHODS: A retrospective review of 19 cases of surgically treated snowboard-related injury was done. Analyzed parameters included site of injury, type of fracture, peri- and postoperative complications, pre- and postoperative neurological status, activities of daily living, and participation in sports activities at the final follow-up. RESULTS: The major site of injury was the thoracolumbar junction caused by fracture-dislocation (13/19 cases). The remaining 6 cases had cervical spine injuries. Over 60% of the patients had Frankel A and B paralysis. All patients were surgically treated by posterior fusion with instrumentation. Five underwent additional anterior fusion. Surgical outcome was restoration of ambulatory capacity in 12 patients (63.2%). Ultimately, 15 patients (78.9%) could return to work. Patients with complete paralysis upon admission showed reduced ambulatory capacity compared to those with incomplete paralysis. None of the patients again participated in any sports activities, including snowboarding. CONCLUSIONS: Snowboarding-related spinal or spinal cord injury has a great impact on social as well as sports activities. It is necessary to enhance promotion of injury prevention emphasizing the snowboarders' responsibility code.
Activities of Daily Living
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Follow-Up Studies
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Humans
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Paralysis
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Postoperative Complications
;
Retrospective Studies
;
Return to Work
;
Skiing*
;
Spinal Cord Injuries
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Spinal Injuries*
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Spine
;
Sports
9.High Dose Three-Dimensional Conformal Boost Using the Real-Time Tumor Tracking Radiotherapy System in Cervical Cancer Patients Unable to Receive Intracavitary Brachytherapy.
Hee Chul PARK ; Shinichi SHIMIZU ; Akio YONESAKA ; Kazuhiko TSUCHIYA ; Yasuhiko EBINA ; Hiroshi TAGUCHI ; Norio KATOH ; Rumiko KINOSHITA ; Masayori ISHIKAWA ; Noriaki SAKURAGI ; Hiroki SHIRATO
Yonsei Medical Journal 2010;51(1):93-99
PURPOSE: The purpose of this study is to evaluate the clinical results of treatment with a high dose of 3-dimensional conformal boost (3DCB) using a real-time tracking radiation therapy (RTRT) system in cervical cancer patients. MATERIALS AND METHODS: Between January 2001 and December 2004, 10 patients with cervical cancer were treated with a high dose 3DCB using RTRT system. Nine patients received whole pelvis radiation therapy (RT) with a median dose of 50 Gy (range, 40-50 Gy) before the 3DCB. The median dose of the 3DCB was 30 Gy (range, 25-30 Gy). Eight patients received the 3DCB twice a week with a daily fraction of 5 Gy. The determined endpoints were tumor response, overall survival, local failure free survival, and distant metastasis free survival. The duration of survival was calculated from the time of the start of radiotherapy. RESULTS: All patients were alive at the time of analysis and the median follow-up was 17.6 months (range, 4.9-27.3 months). Complete response was achieved in nine patients and one patient had a partial response. The 1- and 2-year local failure free survival was 78.8% and 54%, respectively. The 1- and 2-year distant metastasis free survival was 90% and 72%, respectively. Late toxicity of a grade 2 rectal hemorrhage was seen in one patient. A subcutaneous abscess was encountered in one patient. CONCLUSION: The use of the high dose 3DCB in the treatment of cervical cancer is safe and feasible where intracavitary brachytherapy (ICBT) is unable to be performed. The escalation of the 3DCB dose is currently under evaluation.
Adult
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Aged
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*Brachytherapy
;
Female
;
Humans
;
Middle Aged
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Radiotherapy Planning, Computer-Assisted/adverse effects/*methods
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Treatment Outcome
;
Uterine Cervical Neoplasms/mortality/pathology/*radiotherapy
10.Kampo Medicine for the Treatment of Pain Due to Orthopedic Disorders
Yuzo FUKUSHIMA ; Ryousuke FUJITA ; Rikitoshi UENO ; Kazuhiko YAMASHITA ; Yasuo UTSUMI ; Tomomi SHIMIZU ; Toshiko TODA ; Asami OHMORI
Kampo Medicine 2019;70(1):35-41
In our clinic, patients with relatively positive diseases, which form the orthopedic conditions with inflammation, were successfully treated with eppikajutsuto and daiobotampito after reisenjotsuin. Patients with pain due to orthopedic disorders where NSAIDs (non-steroidal anti-inflammatory drugs) were difficult to be used or ineffective were successfully treated with eppikajutsuto and daiobotampito. We present the representative cases and bibliographically discuss them.