1.An audit study of the sensitivity and specificity of ultrasound, fine needle aspiration cytology and frozen section in the evaluation of thyroid malignancies in a tertiary institution.
Winson J H TAN ; Kaushal SANGHVI ; Kui Hin LIAU ; Cheng Hock LOW
Annals of the Academy of Medicine, Singapore 2010;39(5):359-362
INTRODUCTIONThe aim of this study was to conduct an audit of the sensitivity and specificity of ultrasound, fi ne needle aspiration cytology (FNAC) and frozen section in the evaluation of thyroid malignancies in our practice.
MATERIALS AND METHODSThe medical records of all the patients who underwent thyroid surgery in a tertiary institution's General Surgery Department between January 2005 and December 2007 were retrospectively reviewed using a standardised data collection template. Results of the ultrasounds, FNACs and frozen sections were compared with the fi nal histological diagnosis.
RESULTSA total of 112 patients underwent thyroid surgery in the 3-year study period. Thyroid malignancy constituted 34 (30%) of all patients who underwent thyroid surgery. The most popular diagnostic tools used were ultrasound (81%), FNAC (69%) and frozen section (59%). The sensitivity of ultrasound, FNAC and frozen section were 41.4%, 86.4% and 68.8%, respectively. FNAC was shown to be a superior diagnostic test in detecting malignancy compared to ultrasound. FNAC was able to pick up 53% of thyroid cancers missed by ultrasound. Frozen section was able to pick up 33% of thyroid cancers that were missed by both ultrasound and FNAC.
CONCLUSIONFNAC is the most reliable tool in detecting malignancies and ought to form the mainstay for investigation of thyroid nodules. The utilisation of ultrasonographic features in the evaluation of thyroid nodules might not necessary improve the detection rate of thyroid malignancy. Frozen section helps to improve the detection rate of thyroid malignancy but further studies into its cost-effectiveness ought to be performed.
Adult ; Biopsy, Fine-Needle ; Female ; Frozen Sections ; Humans ; Male ; Medical Audit ; Middle Aged ; Sensitivity and Specificity ; Thyroid Neoplasms ; diagnostic imaging ; pathology ; Ultrasonography
3.Elective incisional hernia repair: lower risk of postoperative wound infection with laparoscopic versus open repair.
Serene Si Ning GOH ; Kaushal Amitbhai SANGHVI ; Aaryan Nath KOURA ; Jaideepraj Krishnaraj RAO ; Aung Myint OO
Singapore medical journal 2023;64(2):105-108
INTRODUCTION:
The superiority of laparoscopic repair over open repair of incisional hernias (IHs) in the elective setting is still controversial. Our study aimed to compare the postoperative outcomes of laparoscopic and open elective IH repair in an Asian population.
METHODS:
This retrospective study was conducted in an acute general hospital in Singapore between 2010 and 2015. Inclusion criteria were IH repair in an elective setting, IHs with diameter of 3-15 cm, and location at the ventral abdominal wall. We excluded patients who underwent emergency repair, had recurrent hernias or had loss of abdominal wall domain (i.e. hernia sac containing more than 30% of abdominal contents or any solid organs). Postoperative outcomes within a year such as recurrence, pain, infection, haematoma and seroma formation were compared between the two groups.
RESULTS:
There were 174 eligible patients. The majority were elderly Chinese women who were overweight. Open repair was performed in 49.4% of patients, while 50.6% underwent laparoscopic repair. The mean operation time for open repair was 116 minutes (116 ± 60.6 minutes) and 139 minutes (136 ± 64.1 minutes) for laparoscopic repair (P = 0.079). Within a year after open repair, postoperative wound infection occurred in 15.1% of the patients in the open repair group compared to 1.1% in the laparoscopic group (P = 0.0007). Postoperative pain, recurrence and haematoma/seroma formation were comparable.
CONCLUSION
Elective laparoscopic IH repair has comparable outcomes with open repair and may offer the advantage of reduced postoperative wound infection rates.
Humans
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Female
;
Aged
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Incisional Hernia/surgery*
;
Surgical Wound Infection/epidemiology*
;
Retrospective Studies
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Seroma/surgery*
;
Herniorrhaphy/adverse effects*
;
Surgical Mesh
;
Recurrence
;
Hernia, Ventral/surgery*
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Laparoscopy/adverse effects*
;
Postoperative Complications/surgery*