Purpose: Head and neck cancer patients receiving chemoradiation therapy often suffer from severe mucositis. Chemoradiation therapy-induced mucositis is usually accompanied by severe and intractable pain that impairs quality of life. To establish an effective method for treatment of mucositis pain, we retrospectively investigated the relationships of radiation dose with severity of mucositis and opioid consumption. We also conducted a survey on satisfaction of pain treatment. Methods: Study 1: Fourteen patients who underwent chemoradiation therapy of 70 Gy for head and neck cancer from 2005 to 2009 participated in the study. The relationship of severity of mucositis with opioid use was studied. Study 2: Seven patients who had mucositis of over grade 3 and had completed radiation therapy participated in the study. We carried out a questionnaire survey about satisfaction of each pain treatment. Results: Study 1: Increase of radiation dose significantly worsened the severity of mucositis. Opioid consumption for treating pain was significantly greater in the pharynx cancer group than in the oral cancer group. Study 2: Oral care treatment was preferred to systemic administration of analgesics including opioids. Conclusions: In the oral cancer group, oral care treatment was thought to be useful for pain treatment. Oral cancer patients needed less opioids than did pharynx cancer patients.

Purpose：The purpose of this study was to identify the determinants of walking ability on the first day after total hip arthroplasty (THA).Methods：We conducted a retrospective study of 78 joints that had undergone primary hemilateral side THA. We calculated the percentage of patients who successfully walked on the first day after THA and then performed a multiple logistic regression analysis, with walking condition on the first day after THA as the dependent variable and age, sex, body mass index, preoperative JOA score, intraoperative blood loss, and difference between preoperative and postoperative hemoglobin levels as independent variables.Result：Fifty-eight percent of the subjects started walking on the first day after surgery, with orthostatic hypotension listed as the most common reason for difficulty in walking. The multiple regression analysis revealed that intraoperative blood loss was significantly associated with walking ability on the first day after THA (p＜0.05).Conclusion：Walking ability on the first day after THA was more dependent on intraoperative blood loss than physical characteristics or preoperative hip function. Results of this study suggest that the amount of intraoperative blood loss is an important factor in determining the safety of early mobilization in THA patients.

Purpose：The purpose of this study was to identify the determinants of walking ability on the first day after total hip arthroplasty (THA).Methods：We conducted a retrospective study of 78 joints that had undergone primary hemilateral side THA. We calculated the percentage of patients who successfully walked on the first day after THA and then performed a multiple logistic regression analysis, with walking condition on the first day after THA as the dependent variable and age, sex, body mass index, preoperative JOA score, intraoperative blood loss, and difference between preoperative and postoperative hemoglobin levels as independent variables.Result：Fifty-eight percent of the subjects started walking on the first day after surgery, with orthostatic hypotension listed as the most common reason for difficulty in walking. The multiple regression analysis revealed that intraoperative blood loss was significantly associated with walking ability on the first day after THA (p＜0.05).Conclusion：Walking ability on the first day after THA was more dependent on intraoperative blood loss than physical characteristics or preoperative hip function. Results of this study suggest that the amount of intraoperative blood loss is an important factor in determining the safety of early mobilization in THA patients.