No abstract available.
Kasabach-Merritt Syndrome*

No abstract available.
Kasabach-Merritt Syndrome*

No abstract available.
Hemangioma ; Kasabach-Merritt Syndrome ; Skin Neoplasms

No abstract available.
Hemangioma ; Kasabach-Merritt Syndrome ; Skin Neoplasms

The objective of this case are: 1. to present the pathophysiology and clinical manifestations of Kasabach- Merrit syndrome; 2. to present the anesthetic implications of a patient with a huge facio-cervico-mediastinal cystic hygroma with hemangioma on the floor of the mouth; 3. and to present alternative technique for positioning the head of this patient for direct laryngoscopy and endotracheal intubation.
Human ; Female ; Infant ; KASABACH-MERRITT SYNDROME ; HEMANGIOMA

Hemangioendothelioma ; Humans ; Infant, Newborn ; Kasabach-Merritt Syndrome ; Sarcoma, Kaposi

No abstract available.
Adult* ; Disseminated Intravascular Coagulation* ; Humans ; Kasabach-Merritt Syndrome*

Hemangioma is the most frequent liver tumor in infancy. The treatment of hepatic hemangioma includes medical, surgical, and non-operative interventional therapy. There are no standard medical regimens currently considered consistently effective. MDMP (megadose methylprednisolone) and alpha-interferon can be used for medical treatment. Interventional occlusion of feeding arteries in symptomatic hepatic hemangioma is considered a safe and effective alternative to early open surgery. Untreated symptomatic patients with heart failure have a high mortality rate. For this reason symptomatic patients with heart failure may require non-operative treatment such as interventional embolization, because hepatic resection is burdened with high risk. We report our experiences of two patients with neonatal liver hemangiomas whose clinical courses were complicated by cardiac failure to whom medical treatment and/or interventional vascular occlusion were done. Both patients had Kasabach-Merritt syndrome complicated with cardiac failure. Initially, the masses were considered unresectable. In one case, we performed interventional therapy in addition to medical treatment. In another case, we tried medical therapy with megadose steroid and alpha-interferon. Unfortunately, in spite of the treatments, the patients died of severe hemorrhage.
Arteries ; Heart Failure ; Hemangioma* ; Hemorrhage ; Humans ; Infant, Newborn* ; Interferon-alpha ; Kasabach-Merritt Syndrome* ; Liver* ; Mortality

We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.
Abdomen ; Dexamethasone ; Hemangioma ; Humans ; Infant ; Kasabach-Merritt Syndrome ; Male ; Platelet Count ; Prednisolone ; Recurrence ; Scrotum ; Skin Neoplasms

No abstract available.
Child ; Humans ; Kasabach-Merritt Syndrome* ; Kidney Failure, Chronic ; Peritoneal Dialysis, Continuous Ambulatory