1.Intracranial Extramedullary Hematopoiesis in Beta-Thalassemia.
Bivek KARKI ; Xu YI-KAI ; Karuna TAMRAKAR ; Wu YUAN-KUI
Korean Journal of Radiology 2012;13(2):240-243
Extramedullary hematopoiesis (EMH) represents tumor-like proliferation of hemopoietic tissue which complicates chronic hemoglobinopathy. Intracranial EMH is an extremely rare occurrence. Magnetic resonance imaging (MRI) offers a precise diagnosis. It is essential to distinguish EMH from other extradural central nervous system tumors, because treatment and prognosis are totally different. Herein, we report the imaging findings of beta-thalassemia in a 13-year-old boy complaining of weakness of left side of the body and gait disturbance; CT and MRI revealed an extradural mass in the right temporoparietal region.
Adolescent
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Brain Diseases/diagnosis/*etiology/surgery
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Diagnosis, Differential
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*Hematopoiesis, Extramedullary
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Humans
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Magnetic Resonance Imaging
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Male
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Tomography, X-Ray Computed
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beta-Thalassemia/*complications
2.Factors influencing the prognosis of patients with multiple intracranial aneurysms in subarachnoid hemorrhage
Tao QUAN ; Xu-Ying HE ; Xi-Feng LI ; Yi-Jing LIU ; Karuna TAMRAKAR ; Zhi-Qiang FA ; Bin LUO ; Xiao-Ao LONG ; Xin ZHANG
Chinese Journal of Neuromedicine 2012;11(2):152-155
Objective To explore the factors that may influence the prognosis of patients with multiple intracranial aneurysms (MIA) in subarachnoid hemorrhage (SAH). Methods A retrospective review was performed to analyze the medical records of 93 patients who had been managed in our department from January 2000 through January 2011 for MIA in SAH. Results The single factor analysis showed that the gender, preoperative Hunt-Hess grade, treatment protocol and a history of hypertension had significant influences on the prognosis of the patients (P<0.05). The multiple linear regression analysis revealed that the preoperative Hunt-Hess grade and treatment protocol were 2 independent risk factors of the prognosis of the patients (P<0.05). Conclusions The preoperative Hunt-Hess grade and the treatment protocol appear to be related to the prognosis of patients with MIA in SAH. Early diagnosis and treatment of ruptured aneurysms, as well as careful observation and proper intervention ofunruptured aneurysms,can result in a satisfactory prognosis in most patients with MIA in SAH.