The author observed and compared the radiographic features of 49 cases of the fibrous dysplasia and 14 cases of the ossifying fibroma in the osteoblastic or mature stage radiologically and histopathologically. The obtained results were as follows: 1. Fibrous dysplasia occurred most frequently in the 2nd decade, but ossifying fibroma in the 3rd and 4th decades, and both lesions occurred with slight predilection in females. 2. In most cases, chief complaints were painless facial swelling. And 61.1% of fibrous dysplasia occurred in the maxilla, 92.9% of ossifying fibroma in the mandible, and most of these lesions occurred in the premolar-molar region. 3. In the mandibular lesions, ossifying fibroma was shown more oval and round shape, but fibrous dysplasia was shown fusiform shape. 4. Fibrous dysplasia was shown homogeneously distributed, complete radiopaque shadow at 63%, and ossifying fibroma was shown concentric, mixed appearance of radiolucent and radiopaque shadow at 92.9%. 5. Fibrous dysplasia was entirely shown poorly outlined and blended to normal surrounding bone, but ossifying fibroma was shown well-defined border. 6. Cortical thinning and expansion were observed in these lesions, but degree of cortical expansion was more severe in ossifying fibroma than fibrous dysplasia. 7. Loss of lamina dura, tooth displacement, and displacement of mandibular canal were observed in both lesions, but root resorption was observed in ossifying fibroma only.
Diagnosis, Differential* ; Female ; Fibroma, Ossifying* ; Humans ; Mandible ; Maxilla ; Osteoblasts ; Root Resorption ; Tooth

The purpose of this study was to obtain information on the clinical and radiographic features of the odontomas in the jaws. For this study, the authors examined and analyzed the clinical records and radiographs of 119 patients who had lesion of odontoma diagnosed by clinical and radiographic examinations. The obtained results were as follows ; 1. Odontoma occurred the most frequently in the 2nd decade(45.4%) and occurred more frequently in males(60.5%) than in females(39.5%). 2. The most common clinical symptom was the delayed eruption of the teeth(34.2%). 3. The type of lesions was mainly observed as compound odontoma(80.8%), and internal pattern of the complex odontoma was unevenly radiopaque(73.9%). 4. The compound odontoma frequently occurred in anterior portion of the maxilla(57.7%) and mandible(30.9%), and complex odontoma frequently occurred in anterior portion of maxilla(34.8%) and posterior portion of mandible(30.5%). 5. The effects on adjacent teeth were impaction of teeth(71.7%) and prolonged retention of deciduous teeth(31.7%). 6. The impaction of the teeth occurred in anterior portion of maxilla(44.2%) amd mandible(19.2%), but root resorption of the adjacent teeth were not seen. 7. The boundary to adjacent structure was well-defined, the lesions appear as radiopaque mass with radiolucent rim.
Humans ; Jaw ; Odontoma* ; Root Resorption ; Tooth

The purpose of the study was to obtain information on the clinical and radiographic features of the fibro-osseous lesions in the jaws. For this study, the author examined and analysed the clinical records and radiographs of 71 cases of 68 patients in fibrous dysplasia diagnosed by clinical and radiographic or histopathological examinations. The obtained results were as followings : 1. Fibrous dysplasia occured most frequently in the 2nd decade(30.0%), ossifying fibroma in the 3rd-4th decades, periapical cemental dysplasia in the 4th decade, and all of three lesions showed slight predilection in females. In most cases, chief complaints were painless facial swelling in fibous dysplasia and ossifying fibroma, and periapical cemental dyplasia was found accidentally in radiographs. 2. Fibrous dysplasia was occured more frequently in maxilla, ossifying fibroma in mandible and both lesions in premolar-molar area. Periapical cemental dysplasia was larger than that of ossifyng fibroma, and the shape of ossifying fibroma was more round and elliptical than fibrous dysplasia whose was fusiform. 3. Fibrous dysplasia was shown homogeneous radiopaque shadow of 57.6% and ossifying fibtoma & periapical cemental dysplasia were shown mixed appearance of radiolucency and radiopacity shadows at 74.2%, 60.0%, respectively. 4. Fibrous dysplasia was entirely shown poorly defined at 87.7%, but ossifying fibroma & periapical cemental dysplasia were shown well outlined at 60.0%, 70.0%, repectively. 5. Cortical thinning and expasion were observed in fibrous dysplasia and ossifying fibroma, and severe in ossifying fibroma than fibrous dysplasia, and those signs were not seen in periapical cemental dysplasia. Loss of lamina dura was dominant in fibrous dysplasia and root resorption was dominant in ossifyingfibroma. Displacement of mandibular canal and the degree of the increase of vertical dimension were alike in both lesions. Displacement of maxillary sinus or nasal cavity, thinning & expansion of the maxiilary sinus were dominant in fibrous dysplasia. 6. Polyostotic fibrous dysplasia was occured at 5.9%, Multiple periapical cemental dysplasia at 43.7%. Occurrence rate in the edentulous area of fibrous dysplasia and ossifying fibroma were 7.0%, 8.6%, respectively.
Female ; Fibroma ; Fibroma, Ossifying ; Fibrous Dysplasia, Polyostotic ; Humans ; Jaw* ; Mandible ; Maxilla ; Maxillary Sinus ; Nasal Cavity ; Root Resorption ; Vertical Dimension

Desmoplastic fibroma is a rare, benign intraosseous fibroblastic tumor, which is locally aggressive. It is osseous counterpart of soft tissue fibromatosis. The authors experienced the patient who complained persistent mouth opening limitation with mild swelling on the left mandibular angle area. After careful analysis of clinical, radiological and histopathological findings, we diagnosed as desmoplastic fibroma of the mandible. The results were as follows: 1. Main clinical symptoms were mouth opening limitation which had been persistent for 9 months and mild swelling on the left mandibular angle area. 2. Radiographs showed the radiolucent lesion and expansion of lingual cortex. CT finding is homogeneous soft tissue mass with expansion of left mandibularramus. Destruction of medial wall of ramus and invasion to adjacent soft tissue is also seen. 3. Histopathologically, plump spindle shaped fibroblasts arranged in bundles or fascicles are observed. The cells of tumor are infiltrating into muscle fiber with destruction of bony trabeculae and merged with surrounding salivary gland.
Fibroblasts ; Fibroma ; Fibroma, Desmoplastic* ; Humans ; Mandible* ; Mouth ; Salivary Glands

Desmoplastic fibroma is a rare, benign intraosseous fibroblastic tumor, which is locally aggressive. It is osseous counterpart of soft tissue fibromatosis. The authors experienced the patient who complained persistent mouth opening limitation with mild swelling on the left mandibular angle area. After careful analysis of clinical, radiological and histopathological findings, we diagnosed as desmoplastic fibroma of the mandible. The results were as follows: 1. Main clinical symptoms were mouth opening limitation which had been persistent for 9 months and mild swelling on the left mandibular angle area. 2. Radiographs showed the radiolucent lesion and expansion of lingual cortex. CT finding is homogeneous soft tissue mass with expansion of left mandibularramus. Destruction of medial wall of ramus and invasion to adjacent soft tissue is also seen. 3. Histopathologically, plump spindle shaped fibroblasts arranged in bundles or fascicles are observed. The cells of tumor are infiltrating into muscle fiber with destruction of bony trabeculae and merged with surrounding salivary gland.
Fibroblasts ; Fibroma ; Fibroma, Desmoplastic* ; Humans ; Mandible* ; Mouth ; Salivary Glands

17-year-old and 14-year-old brothers were referred for evaluation of the cystic lesions on the mandibular anterior area with no symptoms. Neither their mother nor the brothers could recall any past trauma to those areas. Panoramic and intraoral radiographs revealed moderately defined cystic lesions on their mandibular anterior areas. Biopsies on both lesions revealed simple bone cysts. Hereditary cause or familial history of simple bone cysts could not be found in literature review. This case may have been a coincidence. However, further investigation is needed to find the cause of simple bone cysts occurring in patients those are closely related.
Adolescent ; Biopsy ; Bone Cysts ; Humans ; Mothers ; Siblings

PURPOSE: To evaluate cultured human artificial skin as an experimental model for studying radiation effects in vitro. MATERIALS AND METHODS: The skin was constructed by culturing keratinocytes over collagen lattice which made by culturing fibroblasts. Two groups were irradiated to gamma rays at single dose of 25 Gy with or without 3.5% of DMSO. Ultrastructures were investigated by electron microscopy after irradiation. The number of epidermal layers and expression of cytokeratin (CK) 14 and 10 were also seem by light microscopy. RESULTS: At 2 days after irradiation in experimental group without DMSO, necrotic cells were rarely found in the spinosal layer and undercornified cells were visible in the horney layer. Similar findings were also found in experimental group with DMSO but in mild form. The number of epidermal layers in experimental group without DMSO were significantly fewer than other group. CK 14 expressed in all the layer excluding horney layer but CK 10 expressed over 3~4 basal layers. Such patterns of CK expression were similar to all groups. It is suggested that structures of the keratinocytes and epidermal formation could be disturbed by irradiation in artificial skin and that DMSO can protect these damages. CONCLUSION: Therefore this work could be used as an organotypic experimental model in vitro using human cells for studying radiation effect in skin. Furthermore structural findings provided in this study could be used as useful basic data in further study using this model.
Collagen ; Dimethyl Sulfoxide* ; Fibroblasts ; Gamma Rays ; Humans* ; Keratinocytes ; Keratins ; Microscopy ; Microscopy, Electron ; Models, Theoretical ; Radiation Effects ; Skin ; Skin, Artificial*

The review of the literature determines that large osteomas of the mandible are relatively rare. We present a case of a 60-year-old man with painless swelling of the left submandibular area and mild difficulty in breathing. The patient complained that the mass have been progressing slowly for at least 20 years. Radiographic studies showed a giant osteoma that attached to the lingual surface of the left mandibular angle and extended from submandibular space to infratemporal space. After the excision of the tumor the patient made a full recovery.
Humans ; Mandible* ; Middle Aged ; Osteoma* ; Respiration* ; Tomography, X-Ray Computed

PURPOSE: The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. MATERIALS AND METHODS: We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. RESULTS: Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). CONCLUSION: Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.
Dentition ; Humans ; Medical Records ; Molar ; Odontoma ; Prognosis ; Radiography, Panoramic ; Retrospective Studies ; Tooth ; Tooth, Impacted

PURPOSE: To evaluate the efficacy of panoramic radiography by comparing the results of clinical examination with radiographic findings. MATERIALS AND METHODS: We studied 190 patients (20 men and 170 women; mean age, 40 years; range, 22 to 68 years) who visited the health promotion center of Korea Medical Science Institute and were examined both clinically and by panoramic radiography. We compared results from both examinations. Treatment options by clinical examination were described as "no treatment indicated", "treatment of dental caries", "removal of calculus", "treatment of periodontal disease", "prothodontic treatment" and "extraction of the third molar". Findings taken from the panoramic radiography were: dental caries, periapical lesion, alveolar bone loss, calculus deposition, retained root, impaction of the third molar, disease of maxillary sinus, bony change of mandibular condyle, etc. RESULTS: The prevalence of panoramic findings were: 37.9% of dental caries, 17.4% of periapical lesions, 44.7% of alveolar bone losses, 62.6% of calculi deposition, 7.9% of retained roots, 26.8% of third molar impactions, 6.3% of diseases of maxillary sinus, 2.1% of bony changes of mandibular condlye and 35.8% of miscellaneous lesions. Abnormal conditions revealed by panoramic radiography which had not been discovered on clinical examination were: 24.2% of the patients had dental caries, 17.4% had periapical lesions, 7.4% had calculi deposition, 5.3% had retained roots, 15.3% had third molar impactions. The opposite cases were: 5.2% had dental caries, 12.6% had calculi deposition, and 9.5% had third molar impactions. CONCLUSION: The use of panoramic radiography as a supplement to the clinical examination might be a valuable screening technique.
Alveolar Bone Loss ; Calculi ; Dental Caries ; Female ; Health Promotion ; Humans ; Korea ; Male ; Mandibular Condyle ; Mass Screening* ; Maxillary Sinus ; Molar, Third ; Prevalence ; Radiography, Panoramic*