Recent reports suggest that the responses of the detrusor muscle to the hypogastric nerve stimulation and some autonomic drugs may not be identical among various species. In this study, the responses of the isolated detrusor muscle strips of the Amyda Japonica and the rabbit to catecholamines were compared, and the type of the adrenergic-receptors was investigated. The results obtained were as follows : 1. Catecholamines (norepinephrine and epinephrine) evoked only contraction in the isolated detrusor muscle of the Amyda Japonica and relaxation in the preparation of the rabbit. 2. The contraction-response in the Amyda Japonica was blocked in the presence of regitine, an adrenergic alpha-receptor blocking agent. 3. The relaxation-response in the rabbit was abolished by pre-treatment with propranolol, an adrenergic beta-receptor blocking agent. 4. Acetylcholine elicited contraction in both of the isolated detrusor muscle strips of the Amyda japonica and the rabbit, and the response was completely blocked in the presence of atropine. 5. The results described above suggest that catecholamines exert excitatory effect on the detrusor muscle of the Amyda japonica as it contains adrenergic alpha-receptors and inhibitory effect on the same preparation of the rabbit as it contains the adrenergic beta-receptors. Key Word : amyda japonica,alpha receptor, beta receptor.
Acetylcholine ; Atropine ; Autonomic Agents* ; Catecholamines ; Phentolamine ; Propranolol ; Receptors, Adrenergic, alpha ; Receptors, Adrenergic, beta ; Relaxation

No abstract available.
Animals ; Humans ; Rats* ; Regeneration* ; Urinary Bladder*

No abstract available.
Urodynamics*

We tried to analyze the status of 10 units of frozen thawed apheresis platelet concentration by 6% DMSO method for the evaluation of practical applicability. The platelet concentrations were transferred to PL-732(Baxter, USA) cryopreservation bag, and DMSO is added to those bag at slow rate until expected final 6% concentration is achieved, thereafter those were directly placed to -80 degrees C refrigerator for freezing. Someday later from I week to 1 month, those were thawed at 37 degrees C water bath, and then washed by same volume of ABO matched plasma. In the course of cryopreservation, about 7% of platelets were lost and the mean recovery rate of platelet was 93% compared with those of unfrozen status. LDH, the values of platelet lysis, and pH were within normal limits, whereas platelet aggregation test shows decreased aggregation to collagen and ristocetine compared with those of unfrozen status(p<0.05) but they were clinically acceptable. We suggest that the frozen platelets may be useful in a some clinical situation such as hematologic malignancy and solid tumor by autologous transfusion.
Baths ; Blood Component Removal ; Blood Platelets* ; Collagen ; Cryopreservation* ; Dimethyl Sulfoxide* ; Freezing ; Hematologic Neoplasms ; Hydrogen-Ion Concentration ; Plasma ; Platelet Aggregation ; Ristocetin ; Water

The incidence of acute urinary retention in females is very low but the causes are diverse. So, it is important to verify the causative diseases trough history taking, physical examination including neurologic tests and it is essential to find adequate therapeutic modalities. MATERIALS AND METHODS: We experienced 45 female patients who visited under the chief complaint of acute urinary retention and reviewed, evaluated retrospectively or prospectively during 4 years. The patients are divided 1) transient causes: immobilization after surgery, constipation, medications, herpes zoster, psychogenic causes 2) neurologic causes: cerebral concussion, peripheral neuropathy, brain tumor, herniated nucleus pulposus, spinal cord injury, previously undiagnosed diabetes 3) pelvic causes: difficult labor, uterine prolapse,, pelvic bone tumor, vaginal invasion of rectal cancer, imperforate hymen. RESULTS: Screening test were done through physical examination, history taking, routine urinalysis. Most patients recovered voiding after correction of underlying diseases. CONCLUSIONS: The patients who showed persistent retention were further evaluated through neurologic tests, urodynamics, pelvic ultrasonography and serious diseases as blain tumor, polyneuritis, metastaic pelvic bone tumor were diagnosed.
Brain Concussion ; Brain Neoplasms ; Constipation ; Female* ; Herpes Zoster ; Humans ; Hymen ; Immobilization ; Incidence ; Mass Screening ; Neuritis ; Pelvic Bones ; Peripheral Nervous System Diseases ; Physical Examination ; Prospective Studies ; Rectal Neoplasms ; Retrospective Studies ; Spinal Cord Injuries ; Ultrasonography ; Urinalysis ; Urinary Retention* ; Urodynamics ; Uterine Prolapse

No abstract available.

PURPOSE: The Mitrofanoff continent catheterizable stoma is a useful technique in continent reconstruction. Continence is dependent on the formation of a valve mechanism usually in the form of a submucosal tunnel. This mechanism requires careful dissection of the appendix mesentery and may not be appropriate in small bowel pouches, The split cuff nipple technique has been used effectively for ureteral reimplantation into bowel segments, This paper describes the successful combination of these techniques to provide a continent catheterizable stoma. MATERIALS AND METHODS: Five patients(6 cases) have undergone split cuff nipple stoma formation. Appendix was used in 5 cases and ileum was used in 1 case. Underlying disease were 3 bladder cancers and 2 spinal cord injuries. Reservoir was made using 3 patients ileum, 1 right colon and 1 ileocolon. In 3 cases the appendix was brought out through the umbilicus and in another 3 cases the stoma was formed in the right iliac fossa. CONCLUSIONS: The split cuff nipple appendix stoma provides a simple and reliable continent stoma technique, overcoming some of the complexities of reimplantation of the intact appendix. The technique may be suitable for other narrow tubes, mainly the stapled small bowel or gastric tube.
Appendix ; Colon ; Humans ; Ileum ; Mesentery ; Nipples* ; Replantation ; Spinal Cord Injuries ; Umbilicus ; Ureter ; Urinary Bladder Neoplasms ; Urinary Diversion*

Delayed cutaneous hypersensitivity test had been demonstrated to correlate inversely with stage of disease and predict prognosis of tumor. We evaluated the delayed cutaneous hypersensitivity(D.C.H.) with Multitest CMI between the tumor group and normal control group in Department of Urology, Kosin, Medical College Hospital during the period from October 1986 to August 1988. The result were as follows: 1. D.C.H. with Multitest CMI was compared between the normal control and tumor group: mean total score of positive antigens was markedly decreased in the tumor group(11.3mm for tumor, 15.9mm for control p<0.01) and average number of positive reaction was also decreased in the tumor group(2.6 for tumor, 4.2 for control p<0.01). 2. The percentages of energic response were 11.9% for tumor and 0% for control and the incidence of hypoenergy was also increased in the tumor group (34.2% for tumor, 9% for control). 3. The percentages of Warning score were 27.6% for tumor and 6.8% for control. 4. In comparison with each antigens, there were the strongest reaction and the highest reaction with tuberculin in both group (98.3% for control, 82.9% for tumor) while the weakest reaction with tetanus (16.3% for control, 3.9% for tumor). 5. In comparison of D.C.H. between male and female, low cell mediated immunity was observed in female for the average number of positive antigens in control(4.8 for male, 3.7 for female) and for the average store of in tumor (11.7 mm for male, 9.6 mm for female). 6. In D.C.H. between age groups in control, the youth (17-25 years old) showed the strongest reaction (mean total score 19.1 mm) and 26-65 years old group had relatively stable immunity.
Adolescent ; Female ; Humans ; Hypersensitivity* ; Immunity, Cellular* ; Incidence ; Male ; Prognosis ; Tetanus ; Tuberculin ; Urology

A clinical observation was made on 97 patients of renal calculi who were admitted to the Department of Urology, Chonam University Medical School during the 5 years period from January, 1976 to December, 1980. The following results were obtained. 1) The incidence of renal calculi in 97 patients was 38.0% of urolithiasis in 255 patients and 6.8% of 1430 inpatients. The was an increasing tendency of incidence of renal calculi with annual increasing number of inpatients. 2) There were 51 male and 46 female, a ratio of 1.1:1. The age of two thirds patients of renal calculi ranged from 31 to 50 years, with peak age incidence in the fifth decade. 3) Definite past history of urinary calculi was found in 23 cases (23.7%). 4) The clinical symptoms on admission were flank pain in 92.8%, hematuria in 15.4%, frequency in 5.1% and suprapubic pain in 4.1%. 5) Urinalysis revealed hematuria in 77.3%, proteinuria in 54.1%, pyuria in 42.3%, bacteriuria in 28.9% crystalluria in 9.3% and normal in 8.2% 6) There were 42 renal units of right renal stone and 39 renal units of left renal stone with a ratio of 1.1:1. Unilateral renal calculi were found in 81 patients (83.5%). 7) Treatment consisted of pyelolithotomy in 51 patients (52.6%), pyelonephrolithotomy in 11 patients (11.3%), nephrectomy in 4 patients (4.1%) and nephrolithotomy in 3 patients (3.1%) in order. 8) The incidence of stone ranged from 1.1 to 4.0 gm in weight was 50.6%. The mean weight of removed renal calculi was 25.8 gm in nephrectomy, 19.0 gm in pyelonephrolithotomy, 5.7 gm in nephrolithotomy and 4.9 gm in pyelolithotomy. 9) A nephrostomy tube extended into the upper ureter was located in 30 cases (30.9%) and there was no difference in duration of nephrostomy tube inlaying between pyelolithotomy and pyelonephrolithotomy. 10) Postoperative complications were observed in 22 cases (26.2%) and the most common one was remnant stones in 6 cases (27.4%), of which 5 cases had multiple stones overweighed 10.0 gm. 11) The chemical analysis of 43 renal calculi showed calcium oxalate in 14 cases (32.6%), calcium phosphate in 78 cases (16.3%), the mixed type of calcium oxalate and calcium phosphate in 6 cases (14.0%) and the mixed type of calcium oxalate and magnesium phosphate in 5 cases (11.6%). There were 24 single chemical component of stones. As a result, oxalate stone (67.5%) and phosphate stone (55.9%) were prevalent.
Bacteriuria ; Calcium ; Calcium Oxalate ; Female ; Flank Pain ; Hematuria ; Humans ; Incidence ; Inpatients ; Kidney Calculi* ; Magnesium ; Male ; Nephrectomy ; Postoperative Complications ; Proteinuria ; Pyuria ; Schools, Medical ; Ureter ; Urinalysis ; Urinary Calculi ; Urolithiasis ; Urology

Most renal cell carcinomas are solid but contain small cystic areas. Sometimes the cystic component predominates and such lesions are called cystic renal cell carcinomas. The radiographic and pathologic findings of cystic renal cell carcinoma are often more confusing and less specific than the findings of solid renal cell carcinoma. Multilocular cystic renal cell carcinoma is one form of cystic renal cell carcinoma variants and results from intrinsic multiloculated growth. A presumptive diagnosis of multilocular cystic renal cell carcinoma was made preoperatively in a 38-year-old woman and it was treated with radical nephrectomy, so we report this case with brief review of the literatures.
Adult ; Carcinoma, Renal Cell* ; Diagnosis ; Female ; Humans ; Nephrectomy