Recent reports suggest that the responses of the detrusor muscle to the hypogastric nerve stimulation and some autonomic drugs may not be identical among various species. In this study, the responses of the isolated detrusor muscle strips of the Amyda Japonica and the rabbit to catecholamines were compared, and the type of the adrenergic-receptors was investigated. The results obtained were as follows : 1. Catecholamines (norepinephrine and epinephrine) evoked only contraction in the isolated detrusor muscle of the Amyda Japonica and relaxation in the preparation of the rabbit. 2. The contraction-response in the Amyda Japonica was blocked in the presence of regitine, an adrenergic alpha-receptor blocking agent. 3. The relaxation-response in the rabbit was abolished by pre-treatment with propranolol, an adrenergic beta-receptor blocking agent. 4. Acetylcholine elicited contraction in both of the isolated detrusor muscle strips of the Amyda japonica and the rabbit, and the response was completely blocked in the presence of atropine. 5. The results described above suggest that catecholamines exert excitatory effect on the detrusor muscle of the Amyda japonica as it contains adrenergic alpha-receptors and inhibitory effect on the same preparation of the rabbit as it contains the adrenergic beta-receptors. Key Word : amyda japonica,alpha receptor, beta receptor.
Acetylcholine ; Atropine ; Autonomic Agents* ; Catecholamines ; Phentolamine ; Propranolol ; Receptors, Adrenergic, alpha ; Receptors, Adrenergic, beta ; Relaxation

No abstract available.
Animals ; Humans ; Rats* ; Regeneration* ; Urinary Bladder*

No abstract available.
Urodynamics*

We tried to analyze the status of 10 units of frozen thawed apheresis platelet concentration by 6% DMSO method for the evaluation of practical applicability. The platelet concentrations were transferred to PL-732(Baxter, USA) cryopreservation bag, and DMSO is added to those bag at slow rate until expected final 6% concentration is achieved, thereafter those were directly placed to -80 degrees C refrigerator for freezing. Someday later from I week to 1 month, those were thawed at 37 degrees C water bath, and then washed by same volume of ABO matched plasma. In the course of cryopreservation, about 7% of platelets were lost and the mean recovery rate of platelet was 93% compared with those of unfrozen status. LDH, the values of platelet lysis, and pH were within normal limits, whereas platelet aggregation test shows decreased aggregation to collagen and ristocetine compared with those of unfrozen status(p<0.05) but they were clinically acceptable. We suggest that the frozen platelets may be useful in a some clinical situation such as hematologic malignancy and solid tumor by autologous transfusion.
Baths ; Blood Component Removal ; Blood Platelets* ; Collagen ; Cryopreservation* ; Dimethyl Sulfoxide* ; Freezing ; Hematologic Neoplasms ; Hydrogen-Ion Concentration ; Plasma ; Platelet Aggregation ; Ristocetin ; Water

The incidence of acute urinary retention in females is very low but the causes are diverse. So, it is important to verify the causative diseases trough history taking, physical examination including neurologic tests and it is essential to find adequate therapeutic modalities. MATERIALS AND METHODS: We experienced 45 female patients who visited under the chief complaint of acute urinary retention and reviewed, evaluated retrospectively or prospectively during 4 years. The patients are divided 1) transient causes: immobilization after surgery, constipation, medications, herpes zoster, psychogenic causes 2) neurologic causes: cerebral concussion, peripheral neuropathy, brain tumor, herniated nucleus pulposus, spinal cord injury, previously undiagnosed diabetes 3) pelvic causes: difficult labor, uterine prolapse,, pelvic bone tumor, vaginal invasion of rectal cancer, imperforate hymen. RESULTS: Screening test were done through physical examination, history taking, routine urinalysis. Most patients recovered voiding after correction of underlying diseases. CONCLUSIONS: The patients who showed persistent retention were further evaluated through neurologic tests, urodynamics, pelvic ultrasonography and serious diseases as blain tumor, polyneuritis, metastaic pelvic bone tumor were diagnosed.
Brain Concussion ; Brain Neoplasms ; Constipation ; Female* ; Herpes Zoster ; Humans ; Hymen ; Immobilization ; Incidence ; Mass Screening ; Neuritis ; Pelvic Bones ; Peripheral Nervous System Diseases ; Physical Examination ; Prospective Studies ; Rectal Neoplasms ; Retrospective Studies ; Spinal Cord Injuries ; Ultrasonography ; Urinalysis ; Urinary Retention* ; Urodynamics ; Uterine Prolapse

No abstract available.

The majority of hypospadias repairs can now be accomplished in one-stage, providing a better result with reduced morbidity and hospitalization costs. One-stage repair of hypospadias using Hodgson`s type III urethroplasty was performed on 22 of 47 cases with hypospadias treated at the Departrnent of Urology, Chonnam University Hospital during 10 years between 1976 and 1985. The following results were obtained. 1. The age of all 22 patients ranged from 4 to 30 years at the time of operation and about a half of the patients were in the age group between 6 and 10 years. 2. The most common type of hypospadias was penoscrotal one (55%) 3. Associated anomalies were bifid scrotum in 5 cases (23%) and cryptorchidism in 3 (14%). 4. Urinary diversion was performed on all cases with suprapubic Troca Cystocath in 16 cases (73%) and indwelling urethral silastic catheter in 6(27 %). 5. Postoperative complications were partial skin necrosis in 1 cases (4%), urethrocutaneous fistula in 6 (27%) and urethral stricture in 3 (14%). 6. Opening of the external urethral meatus after surgery was unsatisfactory in 5 cases, of which 3 underwent meatal advancement later. Tumors of the epididymis are rare. The most common one is adenomatoid tumor. At least more than two hundred cases have been reported in the literature but only one was reported by us last year in this country. We add another one which is involving bilateral epididymis simultaneously and review literature briefly.
Adenomatoid Tumor ; Catheters ; Cryptorchidism ; Epididymis ; Female ; Fistula ; Hospitalization ; Humans ; Hypospadias* ; Jeollanam-do ; Male ; Necrosis ; Postoperative Complications ; Scrotum ; Skin ; Urethral Stricture ; Urinary Diversion ; Urology

Malignant lymphoma of testis is rare, comprising 5% of all testicular tumor, but it is the most common type of testicular tumor in patients more than 5 years old. And malignant lymphoma of urinary bladder is extremely rare, while the majority of the affected patients fall within the to 60 age 40 group and is more common in female. Prognosis of the testicular lymphoma is very poor, and the interval free of disease is short and 9O % of patients die of generalized lymphoma within 2 years. Although in contrast to other nonepithelial malignant tumor, primary lymphoma of bladder carries a relatively favorable prognosis but secondary or disseminated bladder lymphoma has poor prognosis. This report concerns a case of simultaneous involvement of both testes and bladder by malignant lymphoma, which was treated with bilateral radical orchiectomy, transurethral resection of bladder and anticancer chemotherapy.
Child, Preschool ; Drug Therapy ; Female ; Humans ; Lymphoma* ; Orchiectomy ; Prognosis ; Testis ; Urinary Bladder

Delayed cutaneous hypersensitivity test had been demonstrated to correlate inversely with stage of disease and predict prognosis of tumor. We evaluated the delayed cutaneous hypersensitivity(D.C.H.) with Multitest CMI between the tumor group and normal control group in Department of Urology, Kosin, Medical College Hospital during the period from October 1986 to August 1988. The result were as follows: 1. D.C.H. with Multitest CMI was compared between the normal control and tumor group: mean total score of positive antigens was markedly decreased in the tumor group(11.3mm for tumor, 15.9mm for control p<0.01) and average number of positive reaction was also decreased in the tumor group(2.6 for tumor, 4.2 for control p<0.01). 2. The percentages of energic response were 11.9% for tumor and 0% for control and the incidence of hypoenergy was also increased in the tumor group (34.2% for tumor, 9% for control). 3. The percentages of Warning score were 27.6% for tumor and 6.8% for control. 4. In comparison with each antigens, there were the strongest reaction and the highest reaction with tuberculin in both group (98.3% for control, 82.9% for tumor) while the weakest reaction with tetanus (16.3% for control, 3.9% for tumor). 5. In comparison of D.C.H. between male and female, low cell mediated immunity was observed in female for the average number of positive antigens in control(4.8 for male, 3.7 for female) and for the average store of in tumor (11.7 mm for male, 9.6 mm for female). 6. In D.C.H. between age groups in control, the youth (17-25 years old) showed the strongest reaction (mean total score 19.1 mm) and 26-65 years old group had relatively stable immunity.
Adolescent ; Female ; Humans ; Hypersensitivity* ; Immunity, Cellular* ; Incidence ; Male ; Prognosis ; Tetanus ; Tuberculin ; Urology

Most renal cell carcinomas are solid but contain small cystic areas. Sometimes the cystic component predominates and such lesions are called cystic renal cell carcinomas. The radiographic and pathologic findings of cystic renal cell carcinoma are often more confusing and less specific than the findings of solid renal cell carcinoma. Multilocular cystic renal cell carcinoma is one form of cystic renal cell carcinoma variants and results from intrinsic multiloculated growth. A presumptive diagnosis of multilocular cystic renal cell carcinoma was made preoperatively in a 38-year-old woman and it was treated with radical nephrectomy, so we report this case with brief review of the literatures.
Adult ; Carcinoma, Renal Cell* ; Diagnosis ; Female ; Humans ; Nephrectomy