We evaluated the effect of Kampo (Japanese herbal) medicine for overactive bladder (OAB), exacerbated by coldness. There were 258 OAB patients who visited our clinic between October and November. Thirty-one percent (79 out of 258) of those patients began Kampo treatment with their OAB drugs. Furthermore Kampo medicines for 49% of cases (39 out of 79) were for coldness. The prognosis of coldnesses which were treated by Kampo medicine at the next spring were as follows. An “effective and continued” group accounted for 54%, and an “effective but discontinued” group for 25%. An “ineffective and discontinued” group accounted for21%. There was a significant difference in mean age between the “effective and continued” group (63 ± 7.3) and “effective but discontinued” group (44 ± 11) (p < 0.01). Thus, the QOL of OAB patients should improve with Kampo medicine co-administered with OAB drugs.

Knee swelling after total knee arthroplasty (TKA) is common and can lead to loss of functional performance. The aim of this study was to reveal the factors related to knee swelling after TKA. In total, 86 patients who underwent unilateral TKA were enrolled. Changes in thigh circumference at 0, 5, and 10 cm proximal from upper pole of the patella were evaluated. In addition, age, body mass index, operation time, blood loss volume, C-reactive protein, albumin, and D-dimer levels, and changes in knee flexion were also assessed preoperatively and at 7 days postoperatively. Thigh circumference at all sites increased postoperatively. Changes in thigh circumference at the superior edge of the patella correlated with changes in knee flexion (r =－0.33, p < 0.01). No significant correlation was found between the other factors. In conclusion, this study revealed a correlation between swelling and flexion after TKA, but no correlation between other factors pre-, intra-, or postoperatively. It is thus necessary to consider other factors in the future.