Objective To evaluate color process technioque and application of three-dimensional images coming from spiral CT and to improve the knowledge for color image.Methods The color process were differently applied in all 420 3-D images of spiral CT.Results All 420 images successfully were colored and printed.Conclusion 3-D color images can clearly display and differentiate tissue,organ and disease,it can supply more information for clinical diagnosis.

Objective To evaluate the value of electron beam computed tomography (EBCT) angiography and three-dimensional reconstruction in the diagnosis of aortic aneurysm.Methods 31 patients(24 male,7 female) with aortic aneurysm were performed scanning by EBCT . The scanning methods were contrast enhanced single slice volume scanning(SVS) and continuous volume scan(CVS); the 3D reconstruction methods were multiple planar reconstruction (MPR), maximum intensity projection(MIP), shaded surface display(SSD) and volume rendering(VR).Results Of 31 aortic disease, 7 cases were aortic aneurysm, 19 cases were aortic dissection and 5 cases pseudoaneurysm. 9 patients were performed operation and the diagnosis of EBCT coincided well with the operative findings in all cases. Conclusion EBCT angiography can obtain high quality images. EBCT angiographic findings and 3D imagings are in helpful accurate diagnosis and direct surgical operation. The 3D images can directly show the shape and range of aortic aneurysm and the tears of the dissection of pseudoaneurysm. It may substitute conventional aortic angiography in the diagnosis of aortic disease.

Objective To evaluate the diagnostic value of magnetic resonance imaging (MRI) in the diagnosis of soft tissue sarcoma. Methods Seventy-four soft tissue tumors patients having underwent plain and enhanced MRI scans were selected. A retrospective case-control study was conducted to compare the demographic and MRI characteristics between 32 cases of soft tissue sarcoma and 42 cases of benign soft tissue tumor. The examined MRI characteristics included lesion location, morphology, size, signal uniformity, intratumoral sign, sign outside the tumor and intensity pattern, et al. The MRI characteristics were compared between 2 groups. Results The 32 patients with soft tissue sarcoma included 7 cases with lipoblastoma, 5 cases with pleomorphic undifferentiated sarcoma, 5 cases with fibrosarcoma, 5 cases with synovial sarcoma 5 cases, 4 cases with dermatofibrosarcoma protuberant, 2 cases with low-grade fibromyxoid sarcoma, 2 cases with alveolar soft part sarcoma, 1 case with leiomyosarcoma, and 1 case with histiocytic sarcoma. The 42 patients with benign soft tissue tumor included 15 cases with neurilemmoma, 9 cases with angioma, 8 cases with neurofibroma, 6 cases with lipoma, and 4 cases with angiolipoma. After controlling for the potential confounding effects of sex and age, whether there was high signal on T2WI and whether the tumor boundary was clear can help for distinguishing soft tissue sarcoma and benign tumor. The occurrence of high signal on T2WI was a risk factor for soft tissue sarcomas ( OR=25.05, 95% CI 4.04 to 155.28), and tumors whose boundaries were less clear ( OR=18.84, 95% CI 2.98 to 118.99) and unclear ( OR=26.59, 95% CI 3.79 to 186.71) were more likely to be soft tissue sarcomas compared to those with clear boundaries. Conclusions The MRI characteristics of soft tissue sarcomas can be used for accurate diagnosis of the tumors before treatment.

Objective To evaluate the effect of end-stage renal disease(ESRD)hemodialysis(HD)on the prognosis of elderly patients undergoing drug-eluting stent(DES)implantation.Methods A retrospective trial was conducted on 4219 consecutive patients(＞60 years old)undergoing DES treatment at Guro Hospital of Korea University from March 2003 to July 2021,and those with GFR ≥ 1 5 ml/(min·1.73 m2)but not on dialysis were assigned into the non-ESRD group(n=4102)and the others on dialysis into the ESRD group(n=117).Based on their baseline data,a propensity score matching(PSM)model was established,including 183 cases of the non-ESRD group and 99 cases of the ESRD group.The patients were followed up for 1,3 and 5 years,and the incidences of MACE and other endpoint events were recorded during the period.Kaplan-Meier sur-vival curve was plotted,and PSM and multivariate Cox regression models were employed to verify the endpoint events.Results Before PSM,the elderly ESRD group had obviously larger propor-tions of hypertension,diabetes,peripheral vascular disease and other diagnoses than the elderly non-ESRD group(P＜0.01).Univariate Cox regression analysis showed that ESRD was a risk fac-tor for all-cause mortality in the elderly patients at 1,3 and 5 years after DES implantation(P＜0.05,P＜0.01);a risk factor for MACE at 3 and 5 years after implantation(HR=2.67,95％CI:1.73-4.10,P=0.000;HR=2.65,95％CI:1.79-3.90,P=0.000);and a risk factor for develo-ping TVR,TLR,NTVR and revascularization at 5 years after surgery(P＜0.05,P＜0.01).Kaplan-Meier survival curve showed that the incidence of MACE in the elderly ESRD group was higher than that in the elderly non-ESRD group at 5-year follow-up(Plog rank=0.006).Conclusion ESRD significantly increases the risk of long-term MACE after DES implantation in elderly patients.

BACKGROUND: More than 75 million procedures with intravascular iodine-based contrast media (ICM) are performed worldwide every year, and some patients undergoing these procedures do not have normal thyroid function. The long-term effects of ICM in patients with mild thyroid dysfunction (TD) are unclear. METHODS: This prospective cohort study was conducted in China. Patients with stable angina pectoris with total triiodothyronine (TT3) reduction, normal thyroid-stimulating hormone, and reverse triiodothyronine (rT3) were enrolled and divided into high-dose (≥100 mL ICM) and low-dose groups (<100 mL ICM). We dynamically investigated the trends in thyroid function, rT3, and thyroid antibodies one year after ICM exposure. RESULTS: A total of 154 patients completed 6 months of follow-up and 149 completed 1 year of follow-up. Thyroglobulin antibody (TGAB) levels were elevated in 41 (26.6%) patients before ICM exposure, 11 (7.1%) of whom also had elevated thyroid peroxidase antibody levels. Transient subclinical TD occurred 6 months after ICM exposure; 75.5% (34/45) of post-operative TD occurred in the high-dose group. One patient developed severe hypothyroidism with myxedema, requiring drug intervention 1 year after ICM exposure. The level of rT3 showed no statistically significant changes during post-operative follow-up ( P  = 0.848). The TGAB level decreased at 6th month ( P  < 0.001), but increased at 1 year after ICM exposure ( P  = 0.002). CONCLUSIONS Patients with T3 reduction are at a risk of transient subclinical TD and hypothyroidism after a single large dose of ICM. Follow-up of this population at 9-12 months after ICM exposure is warranted.
Humans ; Contrast Media/adverse effects* ; Prospective Studies ; Hypothyroidism ; Triiodothyronine ; Iodine/adverse effects* ; Thyrotropin ; Thyroxine

OBJECTIVE To establish a method for determination cinoxate and other 30 kinds of sunscreen agents in sunscreen cosmetics by HPLC. METHODS Twenty-one fat-soluble sunscreen agents(1#−21#) were ultrasonically extracted by the mixed solution of methanol-tetrahydrofuran(1∶1), 10 kinds of water-soluble sunscreen agents(22#−31#) were ultrasonically extracted by the mixed solution of methanol-tetrahydrofuran-water(2∶3∶5) from the samples. Agilent Zorbax SB C18(4.6 mm× 250 mm, 5 μm) column was used to separate cinoxate and other fat-soluble sunscreen agents(1#−20#), Agilent Zorbax SB C18(2.1 mm× 100 mm, 3.5 μm) column was used to separate polysiloxane-15(21 #) , Waters Symmetry C18(4.6 mm× 250 mm, 5 μm) column was used to separate 10 water-soluble sunscreen agents. Methanol-isopropanol-water, isopropanol-tetrahydrofuran-water, and methanol-acetonitrile-0.02 mol·L−1 ammonium acetate solution(add phosphoric acid to adjust pH to 5.0) were used as mobile phase in gradient elution respectively. The flow rates were 1.2, 0.5, 1.0 mL·min−1. The detection wavelengths were 358nm(7 #, 11 #) , 295 nm(23#−25#, 27#−31#), 311 nm(other components). The injection volumes were 5 µL(polysiloxane-15) and 10 µL(other component), the column temperature was set at 30℃. RESULTS The linear relationships(r>0.9999) of 31 sunscreen agents were good in corresponding concentration range. The limit of detection were in the range of 0.002%−0.02%. The recoveries of two substrates at three different supplemental levels ranged from 92.4% to 110.3%, with the RSDs of 0.02%−4.5%. Forty batches of domestic and imported sunscreen cosmetics were determined by this method, 17 kinds of approved sunscreen agents were detected, of which polysiloxane-15 were detected in 10 batches of samples. By comparing with the current method in Safety and Technical Standards for Cosmetics(2015 edition) , it was found that the extraction efficiency of fat-soluble sunscreen agents was superior to the current method, the stability of drometrizole trisiloxan was improved, cinoxate, polysiloxane-15 and other 7 kinds of sunscreens were added. CONCLUSION This method is accurate, sensitive and reliable, which can be used for the detection and analysis of sunscreen in sunscreen cosmetics.