1.Study of bone marrow T-lymphocyte activation in patients with systemic lupus erythematosus
Xue-Qin DING ; Kang-Xing ZHOU ; Ling-Yun SUN ;
Chinese Journal of Rheumatology 2000;0(06):-
0.05). In active SLE, the CD3~+HLA-DR~+, CD4~+HLA-DR~+ and CD8~+ HLA-DR~+ cells of BM were all higher than those of peripheral blood in the control group(P
2.Effects of Dietary Protein on the Progression of Early Chronic Renal Failure in Subtotally Nephrectomizid Rets.
Kyo Sun KIM ; Kee Hyuk KIM ; Sang Yun KIM ; Yong Joo KANG ; Won Jae MAENG
Journal of the Korean Society of Pediatric Nephrology 1999;3(1):64-71
Endodermal sinus tumor of the mediastinum is a very rare malignant tumor, usually affecting young adolescents, and its histologic findings are characteristic as that of gonadal germ cell origin. We describe the cytologic finding of fine needle aspiration of mediastinal endodermal sinus tumor in a 19-year-old male patient, comparing with tissue section. The tumor cells in smears were usually in tight clusters with large overlapping cells, which were arranged in a papillary or microacinar pattern, suggesting carcinoma. The tumor cells were large, round or oval with a small amount of cytoplasm which was occasionally vacuolated and had indistinct border. The nuclei were large, pleomorphic, and vesicular with large promi- nent nucleoli. The tissue sections showed typical findings of endodermal sinus tumor. Careful correlation of cytological findings and the serum alpha-fetoprotein level would be helpful to confirm the diagnosis.
Adolescent
;
alpha-Fetoproteins
;
Biopsy, Fine-Needle
;
Biopsy, Needle
;
Carcinoma, Papillary
;
Carcinoma, Squamous Cell
;
Child*
;
Clonorchiasis
;
Cytoplasm
;
Diagnosis
;
Dietary Proteins*
;
Endodermal Sinus Tumor
;
Female
;
Germ Cells
;
Giant Cells
;
Gonads
;
Humans
;
Kidney Failure, Chronic*
;
Male
;
Mediastinum
;
Middle Aged
;
Thyroid Gland
;
Urinary Tract Infections*
;
Urinary Tract*
;
Vesico-Ureteral Reflux*
;
Young Adult
3.The Correlation Between the Smoking and Oxygen Free Radicals in Men.
Yun Jung KANG ; Kyung Jong LEE ; Kyong Bok MIN ; Sun Young LEE
Korean Journal of Health Promotion 2012;12(3):129-136
BACKGROUND: This study aimed to empirically investigate the determinants on oxygen free radical degree which causes biological damage focusing on smoking habit and health behaviors in daily life. METHODS: In this cross-sectional study, the subjects were adult males who submitted free radical tests among the examinees of the comprehensive medical testings at an university hospital in Suwon from 2008 to 2010. Total 497 samples were used in analyses for clarifying the relations of free radical degree to age, smoking, obesity, and other health behaviors. RESULTS: First, the degree of oxygen free radical increases by 0.164 as the age group increases (P<0.05). Second, the degree of oxygen free radical increases by 0.547 as the smoking habit increases (P<0.001). Third, the degree of oxygen free radical increases by 0.087 as the exposure to hazardous factors in workplace increases (P<0.001). CONCLUSIONS: The findings of the study imply that the smoking habit has more great influence on the increase of oxygen free radical in body than any other health behaviors. The causality of free radical to smoking and health behavior was not identified due to the limit of the cross-sectional study so it needs to be studied prospectively in the future.
Adult
;
Cross-Sectional Studies
;
Free Radicals
;
Health Behavior
;
Humans
;
Male
;
Obesity
;
Oxygen
;
Smoke
;
Smoking
4.Factors Influencing Married Immigrant Women's Perceived Health Status: The National Survey of Multicultural Families 2012.
Korean Journal of Women Health Nursing 2015;21(1):32-42
PURPOSE: The purpose of this study was to investigate factors that influence married female immigrants' perceived health status. METHODS: This study was a retrospective review of dataset from the 2012 National Multicultural Family Survey in Korea. Data were analyzed using descriptive statistics, t-tests, an analysis of variance (ANOVA), Pearson correlation analysis, and multiple regression with the data of 3,014 married female immigrants. RESULTS: Multiple regression analysis showed that demographic factors (age, education level, nationality, period of residency in Korea, and residential area), socio-economical factors (monthly family income, employment, support from the government for basic living, and Medicaid), social support factors (marital conflict, satisfaction with family relationships, some one to talk about self or family matters, meeting with homeland friend, and participation in community meeting), and immigration factors (life satisfaction, experience of social discrimination, and difficulties with living and using medical care) were associated with perceived health status. CONCLUSION: It is important to pay closer attention to immigrant women who have low economic status, less social support, experience difficulties with living in Korea and using medical care. An effective support system for this population should be developed in order to help them successfully transition.
Dataset
;
Demography
;
Education
;
Emigrants and Immigrants*
;
Emigration and Immigration
;
Employment
;
Ethnic Groups
;
Family Relations
;
Female
;
Friends
;
Humans
;
Internship and Residency
;
Korea
;
Retrospective Studies
;
Social Discrimination
5.A Study on Assessment of CAPs (Client Assessment Protocols) using MDS-HC 2.0 on City Elderly .
Chang Kyu KANG ; Mu Sik LEE ; Un Young KIM ; Jung Ho PARK ; Jae Sun YUN
Journal of the Korean Academy of Family Medicine 2008;29(12):915-924
BACKGROUND: This study used MDS-HC 2.0 (Minimum Data Set-Home Care) to analyze the health and the state of function of the traveling health objects. This study was intended to make use of it with the basic materials for providing them with traveling health service suited for the requirement on the health of the traveling health objects. METHODS: The subjects of this study were 1160 people (over 65 years) living under management control of local Health Center from September 7th to October 3th, 2006. This study was analyzed with inter RAI program & SPSS/WIN 10.0, chi-square -test, t-test, and ANOVA. RESULTS: The result showed that 8.97 CAPs per an elderly person was identified and the subjects over 60% had an injury problem from a fall, health prevention service, vision, IADL, pain, and cognition. The number of CAPs in general was high in higher age and the less educated, and those without a job. But, in subjects that had a life partner and a spouse, the number of CAPs was low. In CAPs by the distinction of sex, CAPs which was much more in man than women in statistics were the improvement of health, the abuse of alcohol and drinking wine, bedsore, and the weak supply system. CAPs which women had much more were the function of the heart and the lungs, pain, the performance of the doctor's advice, health prevention service, and incontinence of urine and insertion of catheter. According to the results comparing CAPs by the level of the ADL, the number of CAPs was shown that the group of ADL 2 was higher than group ADL 1. The matter in which the traveling health service had to be applied in all both ADL1 and ADL2 was injury from a fall, health prevention service, and vision. Conculsion: MDS-HC is applicable to decide the care needs for health and social service supplies. The results can be further applicable for careplan, and referral criteria in continuum of care service over long-term care spectrums.
Activities of Daily Living
;
Aged
;
Catheters
;
Cognition
;
Continuity of Patient Care
;
Drinking
;
Equipment and Supplies
;
Female
;
Health Services
;
Heart
;
Humans
;
Long-Term Care
;
Lung
;
Pressure Ulcer
;
Referral and Consultation
;
Social Work
;
Spouses
;
Vision, Ocular
;
Wine
6.Effects of Dietary Salt Restriction in the Development of Renal Failure in the Excision Remnant Kidney Model.
Kyo Sun KIM ; Kee Hyuk KIM ; Sang Yun KIM ; Yong Joo KANG ; Won Jae MAENG
Journal of the Korean Society of Pediatric Nephrology 1999;3(2):170-179
So-called sclerosing hemangioma of the lung is a rare benign neoplasm which usually presents with a coin lesion detected through routine chest X-ray. We report two cases showing characteristic cytologic appearances which have been rarely reported. Both cases were young females with coin lesions in the lung. Fine needle aspiration of each case revealed unique but some different cytologic features. Case 1 showed bland-looking polygonal epithelial cells resembling bronchioloalveolar cells having pre- dominantly papillary configurations with loosely arranged solid sheets or isolated cells. Cytoplasms were plump, cyanophilic, and finely granular, with eccentric nuclei, The nuclei were usually monotonous, round-to-ovoid, and vesicular with a small but conspicuous nucleolus. In comparison to case 1, case 2 revealed largely loose pavement-like solid sheets or clusters rather than papillary patterns in the hemorrhagic background. The size of tumor cells were a little smaller than that of case 1. Bronchioloalveolar carcinoma and papillary adenocarcinoma of metastatic origin were considered to be one of the important differential diagnoses with these cytologic features. Histologically, both cases exhibited findings compatible with so-called sclerosing hemangioma of the lung.
Adenocarcinoma, Bronchiolo-Alveolar
;
Adenocarcinoma, Papillary
;
Biopsy, Fine-Needle
;
Cytoplasm
;
Diagnosis, Differential
;
Epithelial Cells
;
Female
;
Humans
;
Kidney*
;
Lung
;
Numismatics
;
Pulmonary Sclerosing Hemangioma
;
Renal Insufficiency*
;
Thorax
7.Renal Effects of a Low Protein Diet and Antihypertensive Drugs on the Progression of Early Chronic Renal Failure in 5/6 Nephrectomized-Rats.
Kyo Sun KIM ; Kee Hyuk KIM ; Sang Yun KIM ; Yong Joo KANG ; Won Jae MAENG
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):125-132
A case of invasive cribriform carcinoma of the breast is presented with fine need- le aspiration cytologic features. The aspiration was performed from a papable 2.0cm mass in the upper outer quadrant of the right breast in a 53 year-old woman. The aspirate showed cellular smear composed of larger three dimensional tight clusters, smaller monolayered loose clusters, and many individual cells on the clean background. In the clusters, the tumor cells were bordering central lumina, quite similar to the cribriform in histology. The tumor cells in the clusters and individual tumor cells had uniform, small and round nuclei. The chromatin was finely granular, and nuclear membrane was smooth. No discernible nucleoli were present (nuclear grade 1-2). Unless the abundance of individual cells and the cribriform growth pattern are recognized in the smear, the cytologic diagnosis of invasive cribriform carcinoma is difficult.
Female
;
Humans
;
Biopsy
8.Research Progress of Proton Transfer Reaction Mass Spectrometry in the Field of Breathing Gas Detection.
Xuehong ZHAO ; Weikang LI ; Kang DU ; Yun SUN ; Wen YANG ; Yan WANG
Journal of Biomedical Engineering 2015;32(6):1374-1379
Breathing gas carries important physiological information. Technology for detection of breathing gas has become a research focus because of the advantages of nondestructive sampling and convenient operation. Proton transfer reaction mass spectrometry (PTR-MS) plays an irreplaceable role because of the advantages of high sensitivity, fast response and good specificity. In this paper, the principle of PTR-MS is introduced first, followed by research progress of PTR-MS in the field of breathing gas detection. Factors influencing the test results are analyzed. Finally, future prospects of development for PTR-MS in the field of breathing gas detection are discussed.
Gases
;
isolation & purification
;
Mass Spectrometry
;
methods
;
Protons
9.Investigation on Purification Process of Intermediate Product ofCaulis Sinomenii fromTong-An Injection
Xiaodong KANG ; Xufang YANG ; Feng LI ; Junchao LIU ; Yun WU ; Yongcheng SUN ; Wei XIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(5):1090-1094
This study was aimed to improve the transfer rate of sinomenine in the intermediate product of Caulis Sinomenii in order to optimize the purification process of intermediate product ofCaulis Sinomenii fromTong-An (TA) injection. The transfer rate of sinomenine and the stability of fingerprints in the intermediate product of Caulis Sinomenii were used as indexes for the investigation on the impact from different pH ofCaulis Sinomenii extract before extraction. The transfer rate of sinomenine was used as an index for the investigation on the impact by different pH of hydrochloric acid created to dry extract solution. The transfer rate of sinomenine was used as an index for the investigation of four separation ways, which included the vacuum filtration, plate and frame filters, high-speed tube separator, and flat direct centrifuge, on the liquid separation of sinomenium acutum acid. The results showed that the pH ofCaulis Sinomenii extract before extraction was 10-11; the transfer rate of sinomenine was the highest in the extraction process and the fingerprints of TA injection was stable. The pH of hydrochloric acid was 2.0-2.5; and the highest transfer rate of sinomenine in acid dissolution process was 92.94%. The high-speed tube separator had the best separation to sinomenium acutum acid-dissolving liquid. The highest transfer rate of sinomenine was 93.34%. It was concluded that the optimized process can effectively improve the transfer rate of sinomenine in the intermediate product ofCaulis Sinomenii. Meanwhile, fingerprints of the product were stable. The process was simple with good repeatability.
10.Expressions of TNF-?,IL-2 and NGF in tears before and after laser in situ keratomileusis
jing-cai, LIAN ; li-qiong, GU ; hai-yun, SHI ; kang-sun, WANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(06):-
0.05).Expressions of IL-2 in tears significantly decreased 1 d,1 week and 1 month after LASIK(P0.05).Compared with the expression of NGF in tears before operation,those of 1 d,1 week,1 month and 3 months after LASIK were significantly increased(P