Objective To analyze the clinical effect of acupuncture combined with speech rehabilitation training in the treatment of dysarthria after stroke.Methods 88 patients with dysarthria after stroke were selected as study subjects,and they were randomly divided into the control group and the treatment group,44 cases in each group. The control group was treated with speech rehabilitation training,and the treatment group was treated with acupuncture combined with speech rehabilitation training.At the end of treatment,the dysarthria efficacy,a number of aand the incidence of adverse reactions were observed and compared between the two groups.Results The cure rate(9.09%) and total effective rate (77.27%)in the control group were significantly lower than those in the treatment group (25.00%,97.73%),and the differences were statistically significant(χ2 =3.94,8.42,all P <0.05).Before treat-ment,there was no significant difference between the two groups in the number of a(P >0.05),after treatment,the number of ain the control group was (7.39 ±3.67),which was significantly lower than (16.32 ±7.83)in the treatment group(t =4.20,P <0.05).The incidence rate of adverse reaction between two groups had no statistically significant difference(χ2 =3.11,P >0.05).Conclusion For post -stroke patients with dysarthria,acupuncture combined with speech rehabilitation training has good treatment effect,and the method can increase the number of aof patients,and has high security,it is worthy of widely application in clinic.

No abstract available.
Animals ; Antibodies* ; Antibodies, Anticardiolipin ; beta 2-Glycoprotein I* ; Mice* ; T-Lymphocytes, Helper-Inducer*

BACKGROUND: Over the past several years, Clostridium difficile has become a major healthcare-associated pathogen. Fecal bacteriotherapy has been reported as an effective intervention for treating recurrent C. difficile infection by restoring the normal intestinal microbiota. METHODS: Articles on fecal bacteriotherapy were collected through PubMed, CINAHL, Cochrane Library, and Web of Science databases using the keywords "Clostridium difficile," "feces," "fecal transplantation," "fecal microbiota transplantation," and "fecal bacteriotherapy." Using a systematic literature review, variables of interest from articles that met the inclusion criteria were extracted and summarized. RESULTS: Among 141 articles that were published in English from January 1, 2000 to August 31, 2012, 8 studies were selected for analysis after assessing the titles, abstracts, and full contents. Fecal bacteriotherapy procedures varied with respect to donor selection, screening, infusion route, and preparation of the suspension. Donors were mostly family members or relatives, and donor screening included tests for blood borne and stool pathogens. Selected infusion routes were colonoscopy (62.5%), nasogastric tube (25%), and enema (12.5%). The success rate was reported to be 73-100%. There was a lack of a standard procedure for fecal bacteriotherapy in all of the selected studies. CONCLUSION: Fecal bacteriotherapy is an effective intervention for combating C. difficile infection that has a high success rate and no adverse effects. This therapy would be helpful for infection control in hospital settings by facilitating early eradication of C. difficile infection.
Clostridium ; Clostridium difficile ; Colonoscopy ; Donor Selection ; Enema ; Feces ; Humans ; Infection Control ; Mass Screening ; Metagenome ; Tissue Donors

Viruses including baculoviruses are obligatory parasites, as their genomes do not encode all the proteins required for replication. Therefore, viruses have evolved to exploit the behavior and the physiology of their hosts and often eoevolved with their hosts over millions of years. Recent comparative analyses of complete genome sequences of baculoviruses revealed the patterns of gene acquisitions and losses that have occurred during baculovirus evolution. In addition, knowledge of virus genes has also provided understanding of the mechanism of baculovirus infection including replication, species-specific virulence and host range. The Bm8 gene of Bombyx mori nucleopolyhedrovirus (NPV) and its homologues are found only in group I NPV genomes. The Autographa californica NPV Acl6 gene is a homologue of Bm8 and, encodes a viral structural protein. It has been shown that Bm8/Ac 16 interacts with baculoviral and cellular proteins. Bm8/Ac 16 interacts with baculoviral IE1 that is facilitated by coiled coil domains, and the interaction with IE1 is important for Bin8 function. Ac16 also forms a complex with viral FP25 and cellular actin and associates with membranes via palmitoylation. These data suggested that this gene family encodes a multifunctional protein that accomplishes specific needs of group INPVs.

Patent ductus arteriosus is a common congenital heart disease in children.Effective and promptly treatment can prevent complications,such as pneumonia,congestive heart failure,infective endocarditic and pulmonary artery hypertension.The treatments include medication,transcatheter intervention and surgery.The vast majority of the patent ductus arteriosus can be cured by transcatheter interventional therapy now.

Objective To observe the clinical effects of treating infantile muscular torticollis with the primary massage therapy of twining manipulation with one finger and by the traditional massage therapy. Methods 300 cases were randomly recruited into a control group (141 cases) and a treatment group (159 cases). The treatment group was treated with primary massage of twining manipulation with one finger, while the control group was treated with conventional massage. Both groups were treated once daily. 20 min for each time, and 15 days constituted one therapeutic course. After 4 therapeutic courses, the changes of the shape and the size of the sternocleidomastoid muscle were detected by two-dimensional supersonic examination, the changes of the stream of blood of the sternocleidomastoid muscle was observed by the colored doppler supersonic observation, and assessed the overall curative effect combined with neck deflection degree and the activity. Results In the treatment group, 33 cases were healed, excellent therapeutic effects were seen in 72 cases, effectiveness were seen in 45 cases, 9 cases were inefficacy, and the total effective rate was 94.34%; In the control group, 9 cases were healed, excellent therapeutic effects were seen in 36 cases, effectiveness were seen in 75 cases, 21 cases were inefficacy, and the total effective rate was 85.11%. The result of the two groups showed a significant difference (P<0.05) .Conclusion Infants muscular torticollis mainly treated by twining manipulation with one finger showed a better result than conventional massage. It can effectively shorten the therapeutic time and avoid the Sequela due to the protraction of disease.

Massage therapy is commonly used in the treatment of infantile muscular torticollis clinically.The massage therapy can reduce the therapeutic course effectively and prevent the occurrence of sequel due to long-term un-heating of the disease.This research provided many manipulative methods of massage in treating infantile muscular torticollis for clinical uses.

Sepsis has become a widespread and very complex issue for modern critical care medicine.It is undoubtedly of great theoretical and clinical significance that we should strengthen the study of sepsis and explore new treatments and drugs.It has been found that curcumin had anti-tumor,anti-inflammatory,anti-virus,antibacterial,antioxidant and other pharmacological effects,low toxicity,and a good potential for clinical application.Moreover,it was thought to be potentially immunomodulatory in the last two decades.A number of experimental studies had elicited that curcumin could be used for sepsis and septic shock.This article reviews the immune regulation mechanism of curcumin in sepsis.

Immunochemotherapy is still the primary drug therapy of renal cell carcinoma(RCC), and chemotherapy is effective too. The combination of gemcitabine and cisplatin is the standard regimen now. How-ever, emerge of targeted therapeutic agents has altered the treatment of RCC. Multitargeted tyrosine kinase in-hibitor, such as sunitinib and sorafenib, and mammalian target of rapamycin (roTOR) inhibitors( temsiroll-mus), and anti-tumor monoclonal antibody, such as bevacizumab, have already become the first line election.

No abstract available.
Positive-Pressure Respiration, Intrinsic ; Airway Resistance ; Bronchitis, Chronic ; Lung Compliance ; Vena Cava, Inferior ; Work of Breathing ; Heart Ventricles ; Blood Pressure ; Pulmonary Disease, Chronic Obstructive ; Lung ; Respiratory Muscles ; Pulmonary Emphysema ; Emphysema ; Pneumonia ; Cardiac Output ; Lung Transplantation ; Intensive Care Units ; Positive-Pressure Respiration ; Barotrauma ; Hypotension ; Korea