1.Perinatal care of 5 pregnant patients with hypoparathyroidism
Modern Clinical Nursing 2017;16(3):12-15
Objective To explore the experience of nursing the patients with hypoparathyroidism.Methods Five pregnant patients with hypoparathyroidism hospitalized in our hospital during January 2009 to December 2015 were included in the study.The nursing intervention included performance of health care during pregnancy,childbirth and postpartum nursing.Results The thyroid function of the 5 patients became normal after medication and delicate care.All underwent cesarean resection and all the infants were normal in terms of thyroid function.Conclusions Pregnancy combined with hypoparathyroidism is of high risk and harmful for mothers and neonates.So they should be under management of high risk pregnancy.The prenatal,intrapartum and postpartum nursing measures should be implemented to ensure the safety of delivery.
2.Effect of ego depletion and emotion regulation on students' health consumption choice
Journal of Shanghai Jiaotong University(Medical Science) 2017;37(5):676-678
Objective · To test the effect of ego depletion and emotion regulation on students' health consumption choice, according to online social network. Methods · The undergraduate students in a university in East China were taken as the researchobject. Public health psychology experiments were designed, using Stroop priming the extent of ego depletion, and SSEIT measuring the extent of emotional regulation. Results · When participants experienced high level ego depletion, for those who possessed weak emotional regulation capability, they were more inclined to select less healthy food(77% vs 18%, χ2=15.40, P=0.000). For those who possessed strong emotional regulation capability, there was no significant difference on food choice between those who experienced high level ego depletion and those who experienced low level ego depletion (40% vs 27%, χ2=0.91, P=0.340).For participants who experienced high level ego depletion, compared to those who overcame ego depletion and those who experienced low level ego depletion, were moreinclined to select less healthy product (69% vs 23%, χ2=11.10, P=0.001), while there was no significant difference between those who experienced low level ego depletion and those who overcame ego depletion (32% vs 23%, χ2=0.51, P=0.470). Conclusion · When students experienced different level ego depletion, they chose different healthy consumption choice because of the different capability of emotional regulation. For students who possessed weak emotional regulation capability, they should be encouraged to choice healthy consumption, and interesting show should be organized to bring them positive emotion. They should also be encouraged to do long-term physical training to overcome the sensitivity tofatigue. Finally, They should be informed to realize the healthy consumption by active communication and interaction such as like, share and comment in social media.
3.Diels-Alder type adducts in stem bark of Morus mongolica
Jie KANG ; Ruoyun CHEN ; Dequan YU
Chinese Traditional and Herbal Drugs 1994;0(07):-
Objective To study the Diels-Alder type adducts in the stem bark of Morus mongolica.Methods The compounds were isolated and purified by silic gel column chromatography,RP18 and Sephadex LH-20.The structures were identified by various spectral evidence.Results Six Diels-Alder type adducts were obtained and they were albanin F(Ⅰ),kuwanon L(Ⅱ),dimoracin(Ⅲ),kuwanon J(Ⅳ),mulberrofuran J(Ⅴ),mulberrofuran Q(Ⅵ).Conclusion Compounds Ⅱ,Ⅲ,and Ⅴ are isolated from the plant for the first time and compounds ⅣⅥ show the anti-oxidation activities.
4.Drainage effects in total knee arthroplasty
Panfeng DONG ; Yueping CHEN ; Jie KANG ; Xiaoyun ZHANG ; Yi RAO
Chinese Journal of Tissue Engineering Research 2014;(17):2649-2654
BACKGROUND:Drainage has been applied as a routine to hip and knee replacement surgery. However, as a potential channel, drainage could become a portal for bacteria and other pathogens to invade the joint cavity. OBJECTIVE:To evaluate the clinical significance and safety of drainage in total knee arthroplasty.
METHODS:The 80 patients were prospectively randomized into two groups:Group 1 included 38 patients with wound drainage;Group 2 included 42 patients without any drainage. According to a formula calculation, blood loss, the number of subjects requiring blood transfusion, volume of blood transfusion, complications and the recovery of function after total knee arthroplasty were statistical y analyzed.
RESULTS AND CONCLUSION:The subjects were fol owed up for 2 years after discharge. Two patients lost to fol ow up in the non-drainage group. 78 patients were involved in the result analysis. The total blood loss, the number of subjects requiring blood transfusion and volume of blood transfusion were more in the drainage group than those in the non-drainage group after surgery. At 3 days after arthroplasty, active range of motion was larger in the drainage group than that in the non-drainage group. No significant differences in hemoglobin levels and Keen Society Score scores were detected after arthroplasty between the two groups. Results suggested that draining wil increase the blood loss and blood transfusion, but it may contribute to the early recovery of knee function. No significant differences in long-period Keen Society Score scores and postoperative complications were detectable between the two groups.
5.A new terpenoid from Ganoderma lucidum.
Chao LIU ; Baoming LI ; Jie KANG ; Hongqing WANG ; Ruoyun CHEN
Acta Pharmaceutica Sinica 2013;48(9):1450-2
A new terpenoid, lucidone D (1), has been isolated from Ganoderma lucidum. Its structure was determined to be 7beta, 15alpha-dihydroxy-4, 4, 14alpha-trimethyl-3, 11, 20-trioxo-5alpha-pregn-8-en on the basis of 1D and 2D-NMR spectral analysis.
6.Relationship between pre-pregnant body mass index and pregnancy growth with maternal and neonatal outcomes
Lulu CHEN ; Jie LIU ; Yu KANG ; Jun LIU ; Sufeng HE
Chongqing Medicine 2014;(10):1178-1180
Objective To explore the effects of the pre-pregnant body mass index(BMI) and the pregnancy growth on the mater-nal and neonatal outcomes .Methods 250 pregnant women with the built file ,regular antenatal inspection and hospital delivery in our hospital during 2011 were selected and divided into the emaciation group ,the appropriate group and the obesity group according to the pre-pregnant BMI .The occurrence rates of cesarean section ,fetal macrosomia ,low birth weight ,postpartum hemorrhage ,ges-tational diabetes ,gestational hypertension disease ,fetal distress ,neonatal asphyxia and puerperal infection were compared among the various groups .In addition ,according to the different growth amplitudes of pregnancy BMI ,the pregnant women were re-divided in-to 3 groups(weight gain insufficient group ,weight gain appropriate group and weight gain overmuch group ) and the different ma-ternal and neonatal outcomes were compared .Results The occurrence rates of cesarean section ,macrosomia ,gestational diabetes and gestational hypertension disease in the obesity group were significantly higher than those in the emaciation group and the appro-priate group(P<0 .05) ,while the occurrence rate of the low birth weight in the emaciation group was significantly higher than that of the appropriate group and the obesity group(P<0 .05);the occurrence rates of cesarean section ,macrosomia ,gestational diabetes and gestational hypertension disease in the weight gain overmuch group were significantly higher than those in the weight gain in-sufficient group and the weight gain appropriate group(P<0 .05) ,while the occurrence rate of low birth weight in the weight gain insufficient group was significantly higher than that of the weight gain appropriate group and the weight gain overmuch group (P<0 .05) .Conclusion The maternal and neonatal outcomes in the pregnant women with pre-pregnant BMI exceeding the standard and pregnant BMI overmuch growth are very worrying .The growth of pre-pregnant BMI and pregnant BMI is one of the important indi-cators for monitoring the maternal and neonatal complications .
7.A retrospective analysis of 374 casualties from the Nepal earthquake
Jie ZENG ; Hua JIANG ; Weijian HU ; Kang CHEN
Chinese Journal of Emergency Medicine 2015;24(10):1086-1090
Objective To analyze the feature of victims transported from Nepal Pokhara's earthquake,and summarized the rescuing experiences got by the Chinese government medical team.Methods A total of 374 casualties from the 2015 Nepal's earthquake magnitude 8.1 transported to the Field Hospital of the Chinese government medical team were classified into four groups according to different causes of injury,and then retrospectively analyzed the types of injury,vital signs,severity of injury and causes of injury.Results Of 374 casualties,the average age was (30.1 ± 12.4) years,and were divided into group A (n =154) in which casualties trapped under ruined buildings,group B (n =123) in which the victims had crushed injury during escaping with their lives,group C (n =58) in which the wounded had injury resulted from fall on the ground during fleeing for their lives and group D (n =39) in which the injury of casualties was caused by fall from high level.Of them,273 patients (296 parts of body injured) suffered from fracture including 34 patients with severe multiple trauma.The average age in the group D (22.3 ±7.4 years old) was significant younger compared with the others (all P < 0.05).The average age in the group C (48.4 ± 13.3 years old) was significant older compared to the others (all P < 0.05).The injury probability was higher for male in the group D (14.2% vs.7.1%,x2 =5.077,P =0.024) and the injury probability was higher for female in the group C (19.7% vs 10.8%,x2 =5.635,P =0.018).The incidence of limbs fracture was highest (66.6%) in all 296 parts of body injured.The incidence of skull fracture in the group B (31.6%) was higher compared to the others (all P<0.05),and the incidence of spinal fracture in the group D (40.0%) was higher compared to the others (all P < 0.05).There was no significant difference in the severe multiple trauma incidence between the group A and the group D (16.9% vs.12.8%,x2 =0.381,P =0.537),but both group A and group D had significant higher incidence of severe multiple trauma compared to the rest two groups (all P < 0.05).The wound debridement was the leading rate of treatment among variety of treatments (57.5%) and the plaster fixation was the second high rate of treatment (30.9%),and the wound infection was found in 25 patients (17.4%) at the first dressing among 144 patients with soft tissue laceration.After active and regular debridement,72% patients' wound smear tests were negative 3 days later,and 100% were negative 7 days later.Conclusions The casualties treated by Chinese government medical team had relatively young average age,not very severe critical illness,and quite high rate of wound infection.The treatment of all kinds of fractures and open wound was a matter of critical importance.Although facing the challenge of incomplete set of medical equipment,the lacking of medicine and many other unexpected problems,the Chinese government medical team successfully fulfilled the mission with the prior experience accumulated from several domestic earthquake disaster rescue actions.
8.Studies on chemical constituents from fruits of Morus alba L.
Xin WANG ; Hongqing WANG ; Jie KANG ; Chao LIU ; Ruoyun CHEN
Acta Pharmaceutica Sinica 2014;49(4):504-6
Chemical investigation of fruits of Mours alba L. lead to the isolation of fifteen compounds by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography. Their structures were determined to be: 1-[5-(2-formlfuryl) methyl] dihydrogen 2-hydroxypropane-1, 2, 3-tricarboxylate 2, 3-diethyl ester (1), 1-[2-(furan-2-yl)-2-oxoethyl] pyrrolidin-2-one (2), divaricataester A (3), methyl 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylate (4), 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylic acid (5), L-pyroglutamic acid (6), L-pyroglutamic acid ethyl ester (7), 3-O-caffeoylquinic acid methyl ester (8), 3-O-caffeoylquinic acid ethyl ester (9), 5-O-caffeoylquinic acid methyl ester (10), 5-O-caffeoylquinic acid ethyl ester (11), 4-O-caffeoylquinic acid methyl ester (12), 4-O-caffeoylquinic acid methyl ester (13), 4-O-caffeoylquinic acid (14), 3-O-caffeoylquinic acid (15), respectively, based on the spectral analysis such as NMR, MS etc. Compounds 1-14 were isolated from this genus for the first time, among which 1 was a new compound.
9.Effects ofSimiaosan on CTGF, BMP-7 Expression in Human Renal Tubular Epithelial Cell Induced by Uric Acid
Jie KANG ; Jicheng CHEN ; Lingyuan ZHANG ; Shanshan DING
Chinese Journal of Information on Traditional Chinese Medicine 2015;(1):73-76
Objective;To explore the mechanism ofSimiaosan drug-containing serum on prevention and treatment of renal fibrosis.Methods Human renal tubular epithelial cells (HK-2) were divided into blank group, model group, control group, and drug-containing serum high dosage group, medium dosage group and low dosage group. The expressions of CTGF and BMP-7 were determined by real-time PCR assay and immunocytochemistry.Results After the HK-2 cell was induced by uric acid (UA), the expression of CTGF significantly increased (P<0.05), the expression of BMP-7 significantly decreased (P<0.05). After intervened bySimiaosan, the expression of CTGF significantly decreased (P<0.05), the expression of BMP-7 significantly increased (P<0.05) and present dosage dependent.Conclusion Reducing the expression of CTGF and up-regulation the expression of BMP-7 and controlling epithelial-myofibroblast transdifferentiation may be the mechanism ofSimiaosan on prevention and treatment of renal fibrosis.
10.The value of contrast enhanced ultrasound in diagnosing type Ⅰ and Ⅱ endoleaks after endovascular abdominal aortic aneurysm repair
Jie ZHANG ; Xiangchen DAI ; Ming XIAO ; Nan KANG ; Jiangqiong CHEN
Chinese Journal of Ultrasonography 2017;26(4):296-301
Objective To investigate the role of contrast enhanced ultrasound (CEUS) in detecting type Ⅰ and Ⅱ endoleaks after endovascular abdominal aortic aneurysm repair (EVAR).Methods PostEVAR patients who met the inclusion criteria were enrolled.All of patients underwent CEUS and computer tomography angiography (CTA) examination.The following parameters were evaluated:ultrasound contrast agent within aneurysmal sac,location and source of endoleaks,wash-in time of endoleaks and stentgraft since contrast agent injection.Analysis was performed to observe different types of endoleak features in CEUS.Results Nine cases were enrolled and all the cases had endoleaks.Three cases were type Ⅰ,6 cases were type Ⅱ.The wash-in time of type Ⅱ endoleaks delayed 9.8 seconds compared to type Ⅰ,and the results of CEUS diagnosis were consistent with CTA.Conclusions CEUS is an effective way to detect endoleaks.This technique can be used as a supplement for CTA in follow-up of post-EVAR patients.