Tolerance to contact hypersensitivity was induced by feeding of different DNCB doses in mice. A total of 40 mice were divided into 4 groups(control group, 6 mg feeding group, 10 mg feeding group, 14 mg feeding group) in experiment I, Degree of tolerance to contact hypersensitivity was rneasured by incremert rate of ear swelling after challenge with DNFB. Experiment 2 was performed in the same method of cxperiment: I with addition of 3 mg DNCB feeding group. The increment ratee were significantly decreased in DNCB feeding groups in experirnent 1 and 2(p<0.0l). But there were no differences statisticalIy between increment rates of DNCB feeding groups.
Animals ; Dermatitis, Contact ; Dinitrochlorobenzene* ; Dinitrofluorobenzene ; Ear ; Mice*

No abstract available.
Ascitic Fluid* ; Endometriosis* ; Female ; Humans ; Interleukins*

The clinical symptom complex characterized by syncopal attacks and sudden death in patients with electrocardiographic anomalies, especially a prolonged Q-T interval is known as the Romano-Ward syndrome. When a similar symptom complex is accompanied by congenital deafness, it is called Jervell and Lange-Nieisen syndrome. This study was undertaken to investigate the investigate the incidence of the latter syndrome in the Seoul area. A total of 1,013 children with congenital deafness who attend schools for the deaf were studied by analyzing their electrocardiograms. A corrected Q-T interval of> or =0.44 seconds was defined as a prolonged Q-T interval. The overall incidence of long Q-T syndrome observed in the deaf in the Seoul area was 0.49% as compared to 0.25% reported from elsewhere in the world. The mean age of patients with long Q-T syndrome was 11.3+/-5.9 years and the first syncopal attacks was 4.6+/-1.1 per patient. A valsalva maneuver and exercise tests in the test group were associated with significant changes in T wave configuration and prolonged Q-T intervals while similar changes were not observed in the control group. A larger survey is needed to derive more statistically significant conclusions.
Child* ; Deafness* ; Death, Sudden ; Electrocardiography ; Exercise Test ; Humans ; Incidence ; Romano-Ward Syndrome ; Seoul ; Valsalva Maneuver

Survey of causes of blindness on 23,249 eye patients who visited to department of Ophthalmology, Han Kang Sacret Heart Hospital, College of Medicine, Hallym University from Jan. 1982 to July 1986 were clinically evaluated. Blindness is defined as visual acuity for distance of 0.1(20/200) or less in the better eye with best correction. Standard Classification of Causes of Blindness recommended from the International Association for the Prevention of Blindness is applied. Estimated number of blindness is 882 persons(1057 blind eyes, 3.80%). For the evaluation of the site of blind eye, 175 persons(19.85%) were binocular and 707 persons(80.15%) were monocular, 375 persons(42.50%) were blind in the right and 332 persons(37.65%) in the left. Distribution of blindness causes by age group is; in male-under 10(3.41%), 11~20(6.06%), 21~30(12.78%), 31~40(10.32%), 41~50(8.42%), 51~60(6.72%), 61~70(5.78%), over 71(4.36%), and in female-under 10(1.80%), 11~20(1.90%), 21~30(4.45%), 31~40(2.65%), 41~50(3.88%), 51~60(5.49%), 61~70(10.13%), over 71(11.92%). Proportion of blindness by causes indicates; Injury and poisoning(31.60%), Senile cataract(28.11%), Infectious disease(9.28%), Others(5.78%), Glaucoma(5.50%), Systemic disease(4.78%), etc. Rate of blindness by site and type of affection is shown as; lens disease(cataract, 37.95%), Corneal disease(10.5%), Glaucoma(5.97%), Phthisis bulbi(5.87%), Anophthalmos(4.93%), Retinal detachment(4.17), etc. Evaluation of result and problems for better reliable survey in future are briefly discussion in comment.
Blindness ; Classification ; Heart ; Humans ; Ophthalmology ; Retinaldehyde ; Telescopes ; Visual Acuity

There have been many reports regarding complications associated with cardiopulmonary resuscitation(CPR) and it may be true that there are many unrevealed complications. Although it is used to say that 'any CPR is better than no CPR', inadvertent or inadequate CPR may insult in serious organ injury. This report describes a 64-year-old woman who suffered Mallory-Weiss tear resulting from inadvertent cardiopulmonary resuscitation by a bystander who had never been trained. Possible mechanisms of gastric injuries caused by CPR are suggested, and importance of adequate CPR training are emphasized in this report.
Cardiopulmonary Resuscitation* ; Female ; Humans ; Mallory-Weiss Syndrome* ; Middle Aged

No abstract available.

We present herein a case of human infestation of canine scabies occuring in a 7l-year-old female patient. Severe pruritic, erythematous papular lesions and excoriation were found over the abdomen, submammary area, and thigh. The itching sensation was aggravated especially at night. Efforts to demonstrate mites from the lesiona of the patient were unsuccessful. Her pet, a small puppy, showed loss of hair and crusted or scaly erythematous patches on the auricles and trunk 1 month prior to her skin lesions. Sarcaptescabiei var. canis were collected from the puppy by brushing the hair snd crusted or scaly patches on its skin. The patient and puppy were treated successfully with application of 25% benzyl benzoate solution.
Abdomen ; Benzoates ; Female ; Hair ; Humans* ; Mites ; Pruritus ; Scabies* ; Sensation ; Skin ; Thigh

We evaluated median value and lower confidence limit of total serum IgE level in each age group of 1,493 pure atopic dermatitis patient without respiratory atopic diseases. The results were as follows . 1. The median value of total serum IgE level of each age group in patients with atopic dermatitis distributed from 56.5 IU/@Ll to 660It.J/C. The distributions of the median value of total serum IgE levels of total patients with atopic dermatitis, total male patients with atopic dermatitis, and total female patients with atopic dermatitis were 185 IU/C, 220 IUj'@C, and 165 IUj'C. There was no statistical significance of median value of total serum IgE level between mole patients and female patients. 2. The 95% and 99% lower confidence limit(one-sided) of total serum IgE level of ea.ch age group in patients with atopic dermatitis distributed from 32.6 IU /n4 to 287IU/v4 and from 31 IU/m0 to 202 IU4. The 95% lower confidence limit (one-sided) of total serum IgE level of total patients with atopic dermatitis, tatal male patients with atopic dermatitis, and. total female patients with atopic dermatitis were 170 II.J/m0, 185 IU,m/l, and 133 IUm/l. The 99% lower confidence limit.(one-sided) of total serum IgE level of total patient with atopic dermatitis, total male patient with atopic dermatitis, and total female patients with atopic dermatitis were 165 IU/ml, 180 IU/ml, and 125 IU/ml.
Dermatitis, Atopic* ; Female ; Humans ; Immunoglobulin E* ; Male

We present herein a case of pyodcrma gangrenosum, who showed good response to clofazimine therapy. The patient, 19-year-old male, had suffered from chronic diarrhea for 10 months before the rapidly spreading pustules and ulcers with undermined purple-to-red borders devkloped on his both lower and upper extremitics. Clofazimine was given orally in a dose of 100mg three times daily for 16 days, and tapered to 100 mg two times daily for the next 11 days. Clinical improvement was noted after 7 day's treatment and the almost all of the skin lesiors were replaced by granulation tissue with epithelizatiori or crust formation after 6 days treatment.
Clofazimine* ; Diarrhea ; Granulation Tissue ; Humans ; Male ; Pyoderma Gangrenosum* ; Pyoderma* ; Skin ; Ulcer ; Young Adult

We present herein two cases of acquired periungual fibrokeratoma occuring beneath the proximal nail folds. A firm duplicated and mitten-shaped protruding mass was found on the left middle finger nail of 38-year-old woman and a firm triplicated and finger-shaped protruding mass was found of the left great toe nail of 46-year-old man. The epidermis of the tumors showed compact hyperkeratosis, focal hypergranulosis, and irregular acanthosis. Thick collagen bundles and dilated capillaries were predominantly oriented in the direction of the longitudinal axis of the lesions. There were no adnexal elements and inflammatory cells in the dermis.
Adult ; Axis, Cervical Vertebra ; Capillaries ; Collagen ; Dermis ; Epidermis ; Female ; Fingers ; Humans ; Middle Aged ; Toes